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Destriman Laoli; Nelvia Mai Susanti; Rahmat Tillah; Betzy Victor Telaumbanua; Ratna Dewi Zebua +3 more

Zoologi: Jurnal Ilmu Peternakan, Ilmu Perikanan, Ilmu Kedokteran Hewan 2024 Asosiasi Riset Ilmu Tanaman dan Hewan Indonesia

This study evaluates the effectiveness of natural materials as antimicrobial agents in the treatment of freshwater fish diseases, with the aim of offering a safer and more sustainable alternative to synthetic chemicals and antibiotics. Using the literature review method, this study analyzed relevant current scientific articles. Results showed that extracts of betel leaf, neem leaf, cinnamon essential oil, basil essential oil, aloe vera, and propolis had significant antimicrobial activity against freshwater fish pathogens such as Flavobacterium columnare and Aeromonas hydrophila. Betel leaf extract and cinnamon essential oil showed inhibition rates of up to 85% and 82%, respectively. The advantages of using natural ingredients include environmental safety, reduced risk of antimicrobial resistance, and immunostimulating effects in fish. However, challenges such as ingredient availability, cost, and standardization still need to be addressed. This study suggests the development of natural ingredient-based products, standardization and quality testing, further research, and training for fish farmers. Collaboration between stakeholders is also important to reduce dependence on antibiotics. In conclusion, natural ingredients have great potential as effective and environmentally friendly antimicrobial agents in freshwater fish health management.    

Alice M CL Luhulima; Aulia Debby Pelu; Jahra Palembang

Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana (JUFDIKES) 2022 Stikes Kesdam IV/Diponegoro Semarang, Indonesia

The rise of disease outbreaks caused by microorganisms such as SARS, bird flu, HIV and COVID-19 has made people use products that contain antiseptics such as soap and hand sanitizer. However, if used continuously it will dissolve the layer of fat and sebum on the skin so that the skin becomes sensitive, dry, and irritated. The development of antiseptic products can be done with natural ingredients such as green betel leaf extract (Piper betle L). It is known that green betel leaf (Piper betle L) has long been used in traditional medicine and can be a natural antiseptic ingredient for making hand sanitizer. This study aims to determine the formulation of hand sanitizer from betel leaf extract (Piper betle L) accompanied by a physical stability test. The materials used in this study were methyl paraben, triethanolamine (TEA), glycerin, aquadest, 95% ethanol, lime juice, green betel leaf extract obtained from the reflux extraction process. The research was conducted by varying the betel leaf extract 55%, 60%, 65%, 70%, 75%. Tests were carried out by covering organoleptic observations (shape, color, odor), pH, homogeneity, dispersion.