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Cytokines and Vitamin K in crohn’s disease patients have been evaluated to discover the conceivable via biomarkers of diagnosed patients compared to control. Sera samples of Eighty patients and control of both genders. forty patients diagnosed crohn’s which the span of age between (20-36) years and 40 healthy volunteers as a control with span age (18-39) years. The patient were guests to Marjan hospital in Babylon city during the period (1/July/2025 to 1/September/2025). The current results showed a significant difference in statistic marks at (P<0.05). Vitamin K in patients below control. There is significance different between values of patients and controls in Magnesium, Calcium, Vitamin K, InterL10 and Toll-like receptor 4. According to word axel, there is magnitude significant relationship among cytokine InterL10 and Toll-like receptor 4, Magnesium, Calcium, & Vitamin K. The cytokines both InterL10 and Toll-like receptor 4 patients’ levels larger than control levels. Calcium and Magnesium which there is significance variance between both patients and Control

High-risk pregnancy is a pregnancy with a number of risk factors that can cause more serious risks or complications and disrupt the pregnancy process until the postpartum period which endangers the life of the mother and fetus, and occurs due to several factors including pregnancies that are too close together, pregnancies with a mother's age that is too young or old, or pregnancies with too frequent births. Too close pregnancy spacing is a pregnancy gap of <24 months (2 years) between the current pregnancy and the previous pregnancy. Based on the midwifery management method described by VARNEY and SOAP, this study aims to offer complete midwifery care services to Mrs. T, from pregnancy to the use of contraceptives, through a qualitative descriptive method with a case study approach. Research findings from the comprehensive midwifery care assessment that has been provided to Mrs. T aged 31 years, in pregnancy found problems spacing of less than 2 years. Mrs. T gave birth spontaneously at Siti Asiyah Bumiayu Hospital with severe preeclampsia. At By. Mrs. T visits I, II, III no problems were found. Mrs. T's postpartum. From 6 hours postpartum to 42 days postpartum, problems were found at the second visit, including hypertension and lower extremity oedema. Proper care from midwives during pregnancy, childbirth, newborn care, postpartum care, and family planning is crucial for the health of both mother and baby.

Premature rupture of membranes (KPD) is the rupture of the membranes before there are signs of labor, and after waiting for an hour the signs of labor have not yet begun. The time from when the membranes rupture until uterine contractions occur is called premature rupture of membranes. Factors that are closely related to PROM include infection, socio-economic factors, blood type factors, smoking behavior, history of PROM, incompetent cervix and intrauterine enhancement that is high or excessively high, fetal disproportion, multigravidity, multiple pregnancies, previous history of PROM , polyhydramnios, trauma, age and parity. The danger of premature rupture of membranes is the possibility of infection in the uterus and premature birth which can increase morbidity and mortality for mother and baby. Premature rupture of membranes causes a direct connection between the outside world and the space in the uterus, making it easier for infection to occur. The aim of this study is to determine the relationship between age and parity with the incidence of premature rupture of membranes in women giving birth at Harapan Bunda Hospital, Batam City in 2023. This research design uses analytical observational with a cross sectional approach, where data is taken using secondary data with a sample size of 65 people. The processing technique uses the chi-square test. The data obtained from the results of statistical tests is with p-value for age = 0.028 and for parity p-value = 0.039. The conclusion of this research is that the majority of mothers give birth at a non-risk age (20-35) and at a parity that is not at risk (2-3). There is a relationship between the age and parity of mothers giving birth and the incidence of KPD at Harapan Bunda Hospital, Batam City in 2023. With the p-value is 0.028 for age and the p-value is 0.039 for parity so that the p-value < α (0.05).

Unhealthy pregnancies will affect the health of the mother and baby, which can lead to fatal pregnancies and even obstructed labor and breastfeeding. So in pregnancy, care is needed during pregnancy which needs to be monitored by carrying out routine ANC so that early examination or detection can be carried out since pregnancy. The aim of the research is to find out in depth what factors influence complications in pregnancy at the Terangun Nursing Health Center in 2024. This research uses a descriptive design with a quantitative type of research using case control research and a retrospective approach where the research takes data from the past. . The research sample was pregnant women who experienced complications and who did not experience pregnancy complications. Research results Age influences the occurrence of complications in trimester pregnancies with the results of the chi-square statistical test on maternal age, namely ρ=0.006<0.05. Parity influences the occurrence of complications in the third trimester of pregnancy with the results of the chi-square test, namely ρ=0.020<0.05. Pregnancy spacing influences the occurrence of complications in the third trimester of pregnancy using the chi-square test, namely ρ=0.018<0.05. Research suggestions: It is hoped that health workers, especially midwives in hospitals, will be able to provide counseling and education regarding the danger signs of complications that may occur in the third trimester of pregnancy..

Perennial rupture is an injury to the birth canal that occurs during the birth of a baby, whether using tools or not using tools. Perineal rupture is caused by parity, gestational spacing, maternal age, perineal stiffness, birth position. baby's weight, vacuum extraction, instrument trauma, episiotomy and wrong bowel movements. Perineal rupture if not treated immediately will cause bleeding. The aim of this study was to determine the relationship between birth weight of babies and the incidence of perineal rupture in mothers giving birth in the Sei Langkai Community Health Center working area, Batam City in 2023. This research design used cross sectional, the sample taken in this study was 30 people. The processing technique uses the Fisher Exact Test. The data obtained from the results of statistical tests is p-value = 0.037. The conclusion of the research is that the characteristics of the mothers giving birth are mostly aged 20-35 years with most parity being multiparous. Most babies are born with a weight that is not at risk (< 4,000 gr). There is a relationship between the birth weight of the baby and the incidence of perineal rupture in the Sei Health Center Working Area. Langkai with a p-value of 0.037 so that the p-value < α (0.05). It is hoped that this research can be used as input and consideration in further research.

Infancy is a golden period as well as a critical period of growth and development, called the golden age because infancy is very short and cannot be repeated. Children's health problems are one of the main problems in the health sector currently occurring in Indonesia. The level of children's health reflects the health level of the nation. Based on these problems, children's health problems are prioritized in nation development planning (Roesli, 2016). The method used in this counseling is a participatory approach, namely approaching local community leaders to obtain permission and support in mobilizing mothers with babies to undergo baby spa (baby massage)..

Abstract and Keywords must be written in English, in italic style, and contain a brief description of the research background, objectives, methods, findings, and implications. The abstract is written in one paragraph with a single space (maximum 200 words), without any reference or formula. The Newborn Period (BBL) is a stage that can be called the golden period as well as a critical phase because during this period there is adaptation to the BBL as well as very rapid growth and development. Therefore, it is important to provide a balanced nutritional menu according to BBL's needs to support adequate baby growth and development. In achieving this, breast milk is the main recommendation given immediately after the baby is born until 6 months. Entering the age of 6 months, the baby's nutritional intake needs will increase, so apart from breast milk, MP-ASI becomes an additional menu for babies to support optimal growth and development. However, MP-ASI must be given according to the baby's age and needs. The application for preparing a balanced nutritional menu for babies is a digital technology that is useful for making it easier for mothers to prepare an appropriate and balanced menu for their little ones. By utilizing the digital application "Baby Meal Planner", it is hoped that baby mothers can independently support government policies in achieving optimal growth and development for the nation's future generations.

Cases of death in infants can be caused by several factors, one of which is Low Birth Weight (LBW). Babies born with low birth weight have a higher risk of experiencing delays in growth and development during childhood, and can even cause death compared to babies born with normal weight. Factors that affect LBW include: baby's length, mother's weight gain, mother's age, LILA, parity, birth spacing, nutritional anemia, and ANC. The purpose of this research is to find out the factors associated with LBW at the Bawangan Ploso Health Center, Jombang Regency, East Java Province in 2020. This research is a quantitative study with a cross sectional approach. The population in this study were all births recorded in the infant cohort data and data on pregnant and giving birth in the Bawangan Ploso Health Center, Jombang Regency for the period January 2020 to December 2020. The number of babies born in that period was 604 babies. Sampling used purposive sampling with a total sample of 100 respondents determined by inclusion and exclusion criteria. The results showed that the baby's length was pertinent to LBW (p = 0,000 < 0,05), maternal weight gain was pertinent to LBW (p = 0,000 < 0,05), maternal age was pertinent to LBW (p = 0,002), LILA was pertinent to LBW (p = 0,000 < 0,05), parity was not pertinent to LBW (p = 0,096 > 0,05), birth spacing was pertinent to LBW (p = 0,000 < 0,05), nutritional anemia was pertinent to LBW (p = 0,000 < 0,05), and ANC was not pertinent to LBW (p = 0,243 > 0,05). Based on the multivariate test, the weight gain of pregnant women is the dominant factor that influences the incidence of LBW.

Abstract. The baby's social emotional development must be a parent's main goal, because if social emotional development does not go well it will affect and hinder other developments such as psychomotor, emotional and other baby development. This research uses a method called critical review, which involves careful examination and evaluation of various sources of information, such as scientific journals, articles, and other media. The main goal of this approach is to improve readers' comprehension and interpretation skills in the field of early childhood development. Infancy is a time of rapid growth and change, infancy is a time of reduced dependency. The developmental tasks of infancy throughout the life span are, learning to eat solid food, learning to walk, learning to talk, learning to control the elimination of body waste, learning sexual differences and procedures, preparing to read, and learning to distinguish right from wrong, and starting to develop conscience. The development of patterns in the changes experienced by individuals since they were still in the womb over a certain life span, namely, weight, height, physical proportions, bones, muscles and fat, body shape, teeth, nervous system, and development of the sense organs. The psychological function of infancy is the period of formation of fundamental psychological patterns for eating, sleeping, and toileting, although the formation of these habits may not be complete by the end of infancy.

Babies need adequate quality sleep because sleep is important for babies to mature their brains. The baby's body will produce growth hormone when sleeping, so the baby needs enough sleep for optimal development. One factor that influences infant development is rest or the length of sleep. To determine the effect of baby massage with fennel oil on the sleep quality of infants aged 3–12 months. Method one group pretest-post-test design. This study consisted of babies who visited intending to do baby massage at the Ananda Ambarawa Baby Spa Clinic in the January-February 2023 period. There were as many as 70 babies, so in a month, there were an average of 35 babies. The sampling technique in this study was purposive sampling, with a population of 35 infants and 32 infants as respondents. The PSQI questionnaire (Pittsburgh Sleep Quality Index) was the research instrument used. Data analysis used the Wilcoxon statistical test. The Wilcoxon statistical test showed that the ρ value was <0.001 <α (0.05). The results of this study indicate that every 1-time baby massage intervention with fennel oil can potentially improve the quality of sleep for babies at 3–12 months of age 4,460 times. This result showed that Ha is accepted. In conclusion, baby massage with fennel oil affects sleep quality in infants aged 3–12 months. It is hoped that midwives can continue to motivate mothers and parents to perform infant massage and can be an additional reference for increasing the knowledge and insights of midwifery students, who are expected to become one of the most effective midwifery interventions to improve infant sleep quality.

In the era of globalization and technological transformation, modern organizations face intergenerational communication challenges due to a diverse workforce spanning from the baby boomer generation to Generation Z. This research highlights the complexity of differences in values, technological preferences, and management styles across generations. The analysis of intergenerational conflicts emphasizes the importance of effective conflict management, while the section on intergenerational communication outlines strategies to address these differences. Research findings identify variations in communication styles, perceptions of values, technological impacts, and conflicts. In conclusion, a profound understanding of intergenerational communication is crucial for productivity and a harmonious work environment in organizations with diverse generations.

The aim of this study was to analyze the results of Hb screening of pregnant women in the third trimester and birth weight. Cross sectional observational research. Population of third trimester pregnant women in the Labuhan Rasoki Health Center area, Southeast Padangsidimpuan District, Padangsidimpuan City. The total sample population was 30 respondents. Data were collected for Hb examination using the Easy Touch GHb tool and weighing newborns. Pearson correlation test data analysis.       Results: Relationship between age and birth weight. Pearson correlation coefficient value (r) -0.464, significance level (p) 0.007, significant between age and birth weight of the baby. Parity with an r value of -0.300, significance level (p) 0.007, is not significant between parity and birth weight. The r value of pregnancy spacing is -0.234. significance level (p) 0.198, there is a significant relationship between pregnancy distance and birth weight. LILA r value is -0.030, significance level (p) 0.869, there is no significant relationship between LILA measurements and birth weight of the baby. Hemoglobin, r value 0.751, significance level (p) 0.058. There is a significant relationship between third trimester Hb levels and baby birth weight.elationship between external factors which are significantly related to birth weight, age, gestational interval and the Hb level of pregnant women. Arm circumference and parity were not related to birth weight. Pregnant women's Hb is checked every trimester, the data supports care planning.

Background : The age of infants and toddlers is the golden age of the period of growth and development of a human being. To stimulate the growth and development of the baby, it is necessary to stimulate the baby. Baby massage and spa are activities to optimize the growth and development of babies. Research objective : to determine the effect of baby massage and baby spa on the growth and motoric development of babies aged 3 to 6 months. Research Methods : This study used a quasi-experimental and pretest and post-test design with a control group. The number of samples of infants aged 3-6 months was 60 babies, 20 babies for the baby massage group, 20 babies for the baby spa group (solus per aqua) and 20 babies who were not treated because their parents refused. The instruments used in this study were baby scales, tape measure and DDST II. Data analysis in this study was the Wilcoxon and Mann Whitney tests. The results of the study: There is an influence of baby massage and baby spa interventions on the growth and motor development of infants aged 3-6 months with p-Value = 0.000 (<0.05). The Mann Whitney test results obtained a p-value of 0.000 (p-value <0.05 at α = 5%), so that it can be concluded that there are differences in the growth and motor development of infants aged 3 to 6 months between the control group and the intervention group (who get baby massage and baby spa). Conclusions and suggestions : It is hoped that baby massage and baby spa can optimize baby growth and development. There is a difference in the effect of giving baby massage and baby spa on the growth and motoric development of infants aged 3-6 months. So that giving actions like this can be routinely carried out to maximize the growth and development of the baby.