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Pine soda is a natural fermented liquid from pine needles (Pinus merkusii) which has a distinctive aroma and contains bioactive compounds with potential as antimicrobial agents. This study aims to determine the antibacterial activity of pine soda against Staphylococcus aureus using the disc diffusion method and to compare its effectiveness with the antibiotic ampicillin as a positive control. The process of making pine soda is carried out through simple fermentation of Pinus merkusii pine needles under certain conditions to produce a fragrant liquid. Furthermore, qualitative tests are carried out to identify the content of bioactive compounds, such as flavonoids, phenols, and essential oils, which are known to have antibacterial properties. In the antibacterial activity test, paper discs that have been soaked in pine soda solutions with graded concentrations (2%, 4%, 6%, 8%, and 10%) are placed on agar media that have been inoculated with S. aureus. The results of the observation showed the presence of inhibition zones in each treatment with varying sizes. The largest inhibition zone was obtained at a concentration of 10% with a diameter of 10 mm, which is included in the medium inhibition category. As a comparison, ampicillin produced an inhibition zone of 26.3 mm, while distilled water, the negative control, showed no inhibition zone. These findings indicate that the antibacterial activity of pine soda is influenced by its bioactive compound content, although its effectiveness is still lower than that of standard antibiotics. This potential opens up opportunities for developing pine soda as a safe natural antibacterial agent, whether in the form of health products such as antiseptics, natural cleaners, or functional beverages that support body health. Further research is needed to optimize the fermentation process, increase the concentration of active compounds, and test its effectiveness against various types of pathogenic bacteria.

Perineal wounds are a common condition experienced by postpartum mothers after vaginal delivery and can potentially cause pain, discomfort, and the risk of infection if not properly cared for. Effective, safe, and culturally appropriate perineal wound care is a crucial need in postpartum care, especially at the primary health care level. Green betel leaves (Piper betle L.) are known to have antiseptic and anti-inflammatory properties that have the potential to support the wound healing process. This study aims to analyze the effect of green betel leaf water baths on the perineal wound healing process in postpartum mothers in the Sikui Community Health Center (UPT) work area. This study used a quantitative quasi-experimental design with a one-group pretest–posttest approach. The study was conducted in June–July 2025 with 18 postpartum mothers with grade I and II perineal wounds as respondents. Wound condition assessment before intervention was carried out using the REEDA instrument as a baseline condition, while healing results were evaluated based on clinical outcomes and the duration of perineal wound healing. Data analysis was conducted descriptively. The results showed that all respondents experienced clinical perineal wound healing after the green betel leaf water bath intervention. The majority of postpartum mothers experienced wound healing in less than one week, with a median healing time of 5.5 days. In conclusion, green betel leaf water bath has the potential to support the perineal wound healing process in postpartum mothers. This intervention can be considered a safe, easy-to-implement, and relevant complementary therapy for integration into postpartum care in primary healthcare settings.

Vegetable ingredients are natural sources of active compounds that have the potential to be used as control agents for pathogenic microorganisms in various fields, including health and agriculture. This study aims to evaluate the synergistic effect between aloe vera (Aloe vera L.) and bandotan (Ageratum conyzoides L.) extracts on inhibiting the growth of pathogenic bacteria in different media. Aloe vera extract is obtained using the infundation method, while bandotan extract is obtained using the maceration technique. The concentrations tested were 30%, 45%, and 60% for each extract, as well as a combination of both. Testing was carried out on two main applications: as an antiseptic hand sanitizer by testing germ colonies using Plate Count Agar (PCA), and as a bacteria control Erwinia carotovora, the cause of carrot tuber rot, using the Path Ways Analysis test. The results showed that the combination of aloe vera and bandotan extracts had more significant inhibitory effectiveness than single extracts in both applications. A combination concentration of 60% gave the best results with a reduction in bacterial colonies of up to 90%. The mechanism of action of active compounds such as flavonoids, phenolics and saponins in this vegetable extract plays an important role in damaging bacterial cell membranes and inhibiting the metabolism of microorganisms. This research confirms the potential of using local plant materials as an environmentally friendly and economical solution for controlling pathogenic bacteria in the health and agricultural sectors.

Sweet arum mango is one type of mango which when harvested has the highest vitamin C content of 7.53 ± 0.4 mg / 100 g. Processed sweet arum mango fruit products that have the potential to be developed are in the form of fruit juice. This is a consideration for researchers to conduct further research on the addition of eugenol preservatives with different concentrations of preservatives and storage times to produce better mango juice. Eugenol compounds have pharmacological activities as analgesics, anti-inflammatory, antimicrobial, antifungal, antiseptic, stimulant, so these compounds are widely used in the pharmaceutical industry. Based on the experimental results, optimal conditions for the use of eugenol occurred until day 2, where the addition of eugenol with treatment 3 as much as 1 ml amounted to 38.82% better when compared to other variations of eugenol addition.  The addition of eugenol preservatives cannot preserve the content of vitamin C in sweet mango juice even the content of vitamin C tends to decrease. Sweet arum mango juice has a shelf life of 12 days and total dissolved solids of more than 20%, so the resulting fruit juice does not meet SNI 7382:2009.

Betel leaves contain phenols that function as powerful antiseptics. Hand sanitizer (HS) is a product that can kill parasites on the hands and is easy to use. Therefore, in this event, education will be provided to the students of SMK Farmasi Surabaya regarding the benefits of betel leaves, followed by a training session on making hand sanitizers containing extract. The participant's level of understanding is evaluated by comparing the scores obtained before and after receiving information from the speaker. A questionnaire is given to allow participants to evaluate the overall conduct of the event, and they are invited to try the hand sanitizers prepared by the team. The results show that 76% of the participants achieved higher scores, 24% maintained the same scores, and none of the participants received lower scores compared to the pre-test. Overall, the participants expressed that the event was very beneficial.

Plant classification exists to simplify and clarify the level of kinship and the type of treatment in plant distribution, at the taxonomic level there are family categories, this family in plant taxonomy is a classification system that groups plants based on similarities between their morphology, characteristics, morphology. Euphorbiaceae is a family with flower characteristics hidden in cyathia structures (inflorencia), sap and various sizes. This research is located in Cipeundeuy Village, Bantarujeg District, Majalengka Regency with quantitative analysis using the exploration method in the residents' yards in Cipeundeuy Village. The results of the study found 1 individual of Ephorbia milli, 1 individual of Euphorbia hirta, 1 individual of Pedilanthus tithymaloides, 4 individuals of Acalypha siamensis and 8 individuals of Manihot esculenta from the Euphorbiacea family. This plant is used as an ornamental plant and can be used as herbal medicine because it has chemical compounds that are antiseptic, anti-inflammatory and antibacterial because it contains tannins, flavonoids and saponins which are effective for healing wounds and several other diseases. The purpose of this research is to inventory and identify plants in Cipeundeuy Village so that the systematics of plants in this area can be known.

The rise of disease outbreaks caused by microorganisms such as SARS, bird flu, HIV and COVID-19 has made people use products that contain antiseptics such as soap and hand sanitizer. However, if used continuously it will dissolve the layer of fat and sebum on the skin so that the skin becomes sensitive, dry, and irritated. The development of antiseptic products can be done with natural ingredients such as green betel leaf extract (Piper betle L). It is known that green betel leaf (Piper betle L) has long been used in traditional medicine and can be a natural antiseptic ingredient for making hand sanitizer. This study aims to determine the formulation of hand sanitizer from betel leaf extract (Piper betle L) accompanied by a physical stability test. The materials used in this study were methyl paraben, triethanolamine (TEA), glycerin, aquadest, 95% ethanol, lime juice, green betel leaf extract obtained from the reflux extraction process. The research was conducted by varying the betel leaf extract 55%, 60%, 65%, 70%, 75%. Tests were carried out by covering organoleptic observations (shape, color, odor), pH, homogeneity, dispersion.