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Aprilya Dwi Nur'aini; Aura Giaska Andiny; Haril Saleleubaja; Muhammad Renggi Saputra; Taupik Hidayat +1 more

jurnal ABDIMAS Indonesia 2026 STIKes Ibnu Sina Ajibarang

Family Medicinal Plants (TOGA) are one form of natural resource utilization that can be used as an alternative traditional medicine as well as an effort to improve public health. Medicinal plants are widely used by the community because they are easy to obtain, relatively safe, and have lower costs compared to modern medical drugs. This study aims to examine the utilization of TOGA plants as an effort to improve the health of the people of Kudu Ganting Village through a literature study approach. The method used was a literature review by examining various scientific sources such as books, journals, and research reports related to family medicinal plants. The results of the study indicate that plants such as ginger, turmeric, lemongrass, temulawak, and betel leaves provide various health benefits, including improving body immunity, treating digestive disorders, and functioning as natural antiseptics. Therefore, the utilization of TOGA plants can serve as an effort to improve community health while also making productive use of home yard land.

Nerdy Nerdy; Nilsya Febrika Zebua; Rini Karlina Putri Zega; Nabilah Dinda Ramadani; Sara Ariska Purba +2 more

Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam 2026 Pusat riset dan Inovasi Nasional

This study aims to comprehensively evaluate the potential pharmacological activities and safety profiles of seven secondary metabolite compounds (Caffeic Acid, Syringic Acid, Quercetin, Luteolin, p-Coumaric Acid, Ferulic Acid, and Epicatechin) identified in the Bajakah plant (Spatholobus littoralis Hassk.). The research approach integrates in silico analysis using the PubChem database, biological activity prediction via PASS Online, oral toxicity assessment through ProTox-II, and pharmacokinetic evaluation using pkCSM, which were subsequently validated through an empirical literature review. The results indicate that these compounds exhibit significant activity probabilities, particularly as antimutagenic, antiseptic, and antioxidant agents. Luteolin demonstrated the highest antimutagenic potential, while Quercetin showed dominant antioxidant activity. Toxicity profiling revealed that Luteolin and Caffeic Acid possess the highest safety levels (Class 5), whereas Quercetin requires special attention (Class 3). These computational findings strongly correlate with empirical evidence demonstrating that Bajakah extract exhibits broad-spectrum antibacterial activity against Staphylococcus aureus, antifungal activity against Candida albicans, as well as high antioxidant and anti-inflammatory capacities. This study provides a strong molecular foundation for the development of Bajakah as a safe and effective phytopharmaceutical candidate.

Tifani Hadi Tri Wahyuni

Sevaka : Hasil Kegiatan Layanan Masyarakat 2026 STIKES Columbia Asia Medan

The landslide disaster that occurred in Tetumpun Village in June 2025 forced 45 families to take refuge. The evacuation conditions with limited access to clean water and sanitation posed high risks to reproductive organ hygiene problems among women. This community service activity aims to increase knowledge and skills of refugee mothers in maintaining reproductive organ hygiene. Implementation methods included reproductive health education, hygiene practice demonstrations, and distribution of hygiene kits. The activity was conducted for 1 day on July 15, 2025 and attended by 18 refugee mothers. Results showed an increase in participants' knowledge from an average of 52.78 (poor category) to 78.89 (good category) with an increase of 26.11 points (49.4%). All participants (100%) were able to practice proper reproductive organ cleaning methods after demonstration. Each participant received a hygiene kit containing sanitary pads, antiseptic soap, underwear, and other hygiene supplies. This activity successfully increased the capacity of refugee mothers in maintaining reproductive organ hygiene despite limited conditions.

Agistha Dwi Lestari; Ardi Mustakim

Jurnal Cakrawala Pendidikan dan Biologi 2025 Asosiasi Riset Ilmu Pendidikan Indonesia

Pine soda is a natural fermented liquid from pine needles (Pinus merkusii) which has a distinctive aroma and contains bioactive compounds with potential as antimicrobial agents. This study aims to determine the antibacterial activity of pine soda against Staphylococcus aureus using the disc diffusion method and to compare its effectiveness with the antibiotic ampicillin as a positive control. The process of making pine soda is carried out through simple fermentation of Pinus merkusii pine needles under certain conditions to produce a fragrant liquid. Furthermore, qualitative tests are carried out to identify the content of bioactive compounds, such as flavonoids, phenols, and essential oils, which are known to have antibacterial properties. In the antibacterial activity test, paper discs that have been soaked in pine soda solutions with graded concentrations (2%, 4%, 6%, 8%, and 10%) are placed on agar media that have been inoculated with S. aureus. The results of the observation showed the presence of inhibition zones in each treatment with varying sizes. The largest inhibition zone was obtained at a concentration of 10% with a diameter of 10 mm, which is included in the medium inhibition category. As a comparison, ampicillin produced an inhibition zone of 26.3 mm, while distilled water, the negative control, showed no inhibition zone. These findings indicate that the antibacterial activity of pine soda is influenced by its bioactive compound content, although its effectiveness is still lower than that of standard antibiotics. This potential opens up opportunities for developing pine soda as a safe natural antibacterial agent, whether in the form of health products such as antiseptics, natural cleaners, or functional beverages that support body health. Further research is needed to optimize the fermentation process, increase the concentration of active compounds, and test its effectiveness against various types of pathogenic bacteria.

Safriana; Melati Yulia Kusumastuti; Enny Fitriani; Abro; Asmaida Nasution +3 more

Sevaka : Hasil Kegiatan Layanan Masyarakat 2025 STIKES Columbia Asia Medan

Antiseptic hand wash liquid soap is a soap that contains certain chemicals to reduce and prevent bacterial infections. Hand washing liquid soap that uses natural ingredients from lemongrass plants (Cymbopogon nardus) has a variety of significant benefits and functions. Lemongrass (Cymbopogon nardus) contains essential oils with antibacterial and antimicrobial properties, making it effective in killing germs and bacterial on hands. This is very important in preventing the spread of disease, especially in vulnerable environments. This hand wash liquid soap is also safe for the skin, reducing the risk of irritation that often occurs due to the use of chemical hand wash liquid soap, and is suitable for all skin types including sensitive skin. The use of lemongrass (Cymbopogon nardus) based hand washing liquid soap for the community is very broad. In addition to serving as an educational tool in public health campaigns, this product also supports the local economy by utilizing raw materials from local farmers, thus promoting sustainable agriculture and creating jobs. With the increasing awareness of the importance of hand hygiene, this liquid hand soap is a healthy alternative for consumers who care about health and the environment. Overall, the use of lemongrass (Cymbopogon nardus) based hand wash liquid soap not only contributes to individual health, but also improves the quality of life of the community through disease prevention and support to the local economy.

Jusuf Leiwakabessy; Delsi Pattinasarany; Vallery Kustianti Marriot Masbait; Ibnu Salman Hasan; Sanfia Fella Masahe +2 more

Jurnal Pengabdian Masyarakat Waradin 2025 Sekolah Tinggi Ilmu Ekonomi Pariwisata Indonesia Semarang

Minor wounds, such as abrasions, scratches, or small cuts, are commonly experienced by teenagers, especially in school environments. However, improper treatment of minor wounds can lead to infections and more severe complications. This study aims to raise awareness and educate students at SMP Negeri 1 Kairatu on the proper management of minor wounds. The research employs a descriptive approach with an interactive educational method involving presentations, discussions, and live demonstrations. Respondents in this study were students from grades 7 to 9. The results indicated that prior to the socialization, most students had inadequate knowledge regarding proper wound care, often resorting to inappropriate methods (e.g., using toothpaste or oil). After the educational intervention, there was an 85% increase in students’ understanding of proper wound management, such as cleaning wounds with clean water, applying antiseptics, and covering wounds with sterile bandages. The socialization program also successfully raised awareness among students about the importance of wound hygiene to prevent infections. Thus, this initiative proved effective in enhancing teenagers' knowledge of proper wound care practices.

Rima Puspita Dewi; Reny Retnaningsih

Jurnal Ilmu Kesehatan dan Gizi 2025 Pusat Riset dan Inovasi Nasional

Perineal wounds are a common condition experienced by postpartum mothers after vaginal delivery and can potentially cause pain, discomfort, and the risk of infection if not properly cared for. Effective, safe, and culturally appropriate perineal wound care is a crucial need in postpartum care, especially at the primary health care level. Green betel leaves (Piper betle L.) are known to have antiseptic and anti-inflammatory properties that have the potential to support the wound healing process. This study aims to analyze the effect of green betel leaf water baths on the perineal wound healing process in postpartum mothers in the Sikui Community Health Center (UPT) work area. This study used a quantitative quasi-experimental design with a one-group pretest–posttest approach. The study was conducted in June–July 2025 with 18 postpartum mothers with grade I and II perineal wounds as respondents. Wound condition assessment before intervention was carried out using the REEDA instrument as a baseline condition, while healing results were evaluated based on clinical outcomes and the duration of perineal wound healing. Data analysis was conducted descriptively. The results showed that all respondents experienced clinical perineal wound healing after the green betel leaf water bath intervention. The majority of postpartum mothers experienced wound healing in less than one week, with a median healing time of 5.5 days. In conclusion, green betel leaf water bath has the potential to support the perineal wound healing process in postpartum mothers. This intervention can be considered a safe, easy-to-implement, and relevant complementary therapy for integration into postpartum care in primary healthcare settings.

Ruswati Ruswati; Titin Supriyatin; Gilang Pranajasakti

Jurnal Pengabdian Sosial 2025 Lembaga Pengembangan Kinerja Dosen

Diabetes Mellitus is a metabolic disease caused by problems in the body in producing insulin, insulin produced is lacking or nonexistent, or it can be due to the insulin receptor not functioning so that cells cannot receive glucose for metabolism (Black, M. J. & Hawks, 2014; Pranata, S & Khasanah, 2017). Diabetic wounds are caused by infection as a result of high blood glucose, thereby increasing bacterial proliferation, and added to the deficiency of the immune system which causes the wound inflammation period to last a long time. In addition, inappropriate treatment of diabetic wounds (ulcers) can worsen the condition of the wound (Ekaputra, 2013). Therefore, proper and optimal wound care is needed. The wound care method that is currently developing is moist wound healing, which is more effective than conventional methods because it is easy to install, can adjust to the shape of the wound, easy to remove, comfortable to wear, does not need to change dressings frequently, absorbs drainage, presses and immobilizes wounds, prevents new wounds from mechanical injury, prevents infection, improves hemostasis by pressing the dressing. Wound care procedures through Debridement and dressing. Wound debridement can accelerate healing by removing necrotic tissue, particulates, or foreign material, and reducing the bacterial load. The conventional method is to use a scalpel and cut away all unwanted tissue including callus and eschar. Saline-moistened (wet-to-dry) gauze dressings; moisture-retaining dressings (hydrogels, hydrocolloids, hydrofibers, transparent films and alginates) that provide physical and autolytic debridement respectively; and antiseptic dressings (silver dressings, cadexomer). Newer advanced dressings are being studied, such as Vulnamin gel made from amino acids and hyaluronic acid used in conjunction with elastic compression have shown positive results.

Rezky Maulidiya; Ardi Mustakim

Mikroba : Jurnal Ilmu Tanaman, Sains Dan Teknologi Pertanian 2025 Asosiasi Riset Ilmu Tanaman Dan Hewani Indonesia

Vegetable ingredients are natural sources of active compounds that have the potential to be used as control agents for pathogenic microorganisms in various fields, including health and agriculture. This study aims to evaluate the synergistic effect between aloe vera (Aloe vera L.) and bandotan (Ageratum conyzoides L.) extracts on inhibiting the growth of pathogenic bacteria in different media. Aloe vera extract is obtained using the infundation method, while bandotan extract is obtained using the maceration technique. The concentrations tested were 30%, 45%, and 60% for each extract, as well as a combination of both. Testing was carried out on two main applications: as an antiseptic hand sanitizer by testing germ colonies using Plate Count Agar (PCA), and as a bacteria control Erwinia carotovora, the cause of carrot tuber rot, using the Path Ways Analysis test. The results showed that the combination of aloe vera and bandotan extracts had more significant inhibitory effectiveness than single extracts in both applications. A combination concentration of 60% gave the best results with a reduction in bacterial colonies of up to 90%. The mechanism of action of active compounds such as flavonoids, phenolics and saponins in this vegetable extract plays an important role in damaging bacterial cell membranes and inhibiting the metabolism of microorganisms. This research confirms the potential of using local plant materials as an environmentally friendly and economical solution for controlling pathogenic bacteria in the health and agricultural sectors.

Meilatul Maftukhah; Rizki Wahyuning Damayanti

Ebisnis Manajemen 2024 Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

The current phenomenon of product boycotting has caused several industrial products in Indonesia to be boycotted. Such as Lifebuoy products from the Unilever brand because they are considered to support Israeli Zionists. Unilever is a Fast Moving Consumer Goods industry that provides consumer goods with a fluctuating sales cycle. Where Lifebuoy is one of the products from this brand in the antiseptic bath soap category which has a superior Top Brand Index compared to other brands. This research is quantitative research whose calculations involve statistical numbers using the IBM SPSS Statistics 27 application.Who has a purpose to determine the influence of brand image and price on purchasing decisions for Lifebuoy products from the Unilever brand in Indonesia partially or simultaneously. Based on the results of the t test, it shows that brand image has an influence on purchasing decisions by 4.906. And the price variable has an influence on purchasing decisions by 10.374, while the results of the f test show that brand image and price variables have an influence on purchasing decisions by 328.524. And based on the research that has been conducted, it can be concluded that brand image and price influence the decision to purchase Lifebuoy products partially or simultaneously with an Adjusted R Square value of 0.725 or 72.5%.    

Ery Fatarina Purwaningtyas; Wafik Nur Maulina; Sri Mulyaningsih

Venus: Jurnal Publikasi Rumpun Ilmu Teknik 2023 Asosiasi Riset Ilmu Teknik Indonesia

Sweet arum mango is one type of mango which when harvested has the highest vitamin C content of 7.53 ± 0.4 mg / 100 g. Processed sweet arum mango fruit products that have the potential to be developed are in the form of fruit juice. This is a consideration for researchers to conduct further research on the addition of eugenol preservatives with different concentrations of preservatives and storage times to produce better mango juice. Eugenol compounds have pharmacological activities as analgesics, anti-inflammatory, antimicrobial, antifungal, antiseptic, stimulant, so these compounds are widely used in the pharmaceutical industry. Based on the experimental results, optimal conditions for the use of eugenol occurred until day 2, where the addition of eugenol with treatment 3 as much as 1 ml amounted to 38.82% better when compared to other variations of eugenol addition.  The addition of eugenol preservatives cannot preserve the content of vitamin C in sweet mango juice even the content of vitamin C tends to decrease. Sweet arum mango juice has a shelf life of 12 days and total dissolved solids of more than 20%, so the resulting fruit juice does not meet SNI 7382:2009.

Dwi Nor Wardiani; Siti Azizah

JURNAL RISET RUMPUN ILMU HEWANI 2023 Pusat riset dan Inovasi Nasional

Teat dipping is the activity of dipping a dairy cow’s teat into an antiseptic solution was prevent mastitis. Every dairy farmer has different knowledge, attitude and skills. This research to determine the correlation between characteristics, knowledge, and attitude with skills of dairy farmers in teat dipping practices using correlation with SPPS 26. The method used in this research is a descriptive quantitative survey. The study was conducted at KUD Tulus Bakti, Pagu, Kediri from 7 June to 5 September 2021. Respondents in this study were 30 members KUD Tulus Bakti and dairy farmer. The result show that the knowledge and the attitudes of the dairy farmer in this study were categorized as good, and the skills of the dairy farmer in the study were categorized as moderate. Characteristics based on age, education level, number of livestock and farming experience are related to the farmer's skill in teat dipping practice. There is a significant correlation between knowledge and skills of dairy farmer in the practice of teat dipping of KUD Tulus Bakti members, and the level of the correlation is moderate. There is a significant correlation between attitudes and skills of dairy farmer in the practice of teat dipping members of KUD Tulus Bakti, and the level of correlation moderate.

Meyke Herina Syafitri; Mercyska Suryandari; M.A. Hanny Ferry Fernanda

Nusantara: Jurnal Pengabdian kepada Masyarakat 2023 Pusat Riset dan Inovasi Nasional

Betel leaves contain phenols that function as powerful antiseptics. Hand sanitizer (HS) is a product that can kill parasites on the hands and is easy to use. Therefore, in this event, education will be provided to the students of SMK Farmasi Surabaya regarding the benefits of betel leaves, followed by a training session on making hand sanitizers containing extract. The participant's level of understanding is evaluated by comparing the scores obtained before and after receiving information from the speaker. A questionnaire is given to allow participants to evaluate the overall conduct of the event, and they are invited to try the hand sanitizers prepared by the team. The results show that 76% of the participants achieved higher scores, 24% maintained the same scores, and none of the participants received lower scores compared to the pre-test. Overall, the participants expressed that the event was very beneficial.

Fikri Iqlilah Gunawan; Fani Wilma Mulyana; Ateng Supriyatna

Jurnal Riset Rumpun Ilmu Tanaman 2023 Pusat riset dan Inovasi Nasional

Plant classification exists to simplify and clarify the level of kinship and the type of treatment in plant distribution, at the taxonomic level there are family categories, this family in plant taxonomy is a classification system that groups plants based on similarities between their morphology, characteristics, morphology. Euphorbiaceae is a family with flower characteristics hidden in cyathia structures (inflorencia), sap and various sizes. This research is located in Cipeundeuy Village, Bantarujeg District, Majalengka Regency with quantitative analysis using the exploration method in the residents' yards in Cipeundeuy Village. The results of the study found 1 individual of Ephorbia milli, 1 individual of Euphorbia hirta, 1 individual of Pedilanthus tithymaloides, 4 individuals of Acalypha siamensis and 8 individuals of Manihot esculenta from the Euphorbiacea family. This plant is used as an ornamental plant and can be used as herbal medicine because it has chemical compounds that are antiseptic, anti-inflammatory and antibacterial because it contains tannins, flavonoids and saponins which are effective for healing wounds and several other diseases. The purpose of this research is to inventory and identify plants in Cipeundeuy Village so that the systematics of plants in this area can be known.

Alice M CL Luhulima; Aulia Debby Pelu; Jahra Palembang

Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana (JUFDIKES) 2022 Stikes Kesdam IV/Diponegoro Semarang, Indonesia

The rise of disease outbreaks caused by microorganisms such as SARS, bird flu, HIV and COVID-19 has made people use products that contain antiseptics such as soap and hand sanitizer. However, if used continuously it will dissolve the layer of fat and sebum on the skin so that the skin becomes sensitive, dry, and irritated. The development of antiseptic products can be done with natural ingredients such as green betel leaf extract (Piper betle L). It is known that green betel leaf (Piper betle L) has long been used in traditional medicine and can be a natural antiseptic ingredient for making hand sanitizer. This study aims to determine the formulation of hand sanitizer from betel leaf extract (Piper betle L) accompanied by a physical stability test. The materials used in this study were methyl paraben, triethanolamine (TEA), glycerin, aquadest, 95% ethanol, lime juice, green betel leaf extract obtained from the reflux extraction process. The research was conducted by varying the betel leaf extract 55%, 60%, 65%, 70%, 75%. Tests were carried out by covering organoleptic observations (shape, color, odor), pH, homogeneity, dispersion.

Jayanti Djarami; Aulia Debby Pelu; Ainun Pamana

Jurnal Kesehatan Amanah 2021 Universitas Muhammadiyah Manado

The COVID-19 pandemic has made hand sanitizer gel widely used.  Hand sanitizer gels generally contain alcohol as an antiseptic to kill bacteria, but long-term use of antiseptics containing alcohol can cause skin irritation.  So we need natural alternative materials that have antibacterial power but are friendly to the skin and do not cause irritation.  One of theplants that can be used as an antibacterial is a bay leaf (Syzygium polyanthum) because it contains flavonoids that can act as an antiseptic against bacteria. The purpose of this study is to find out the formulation and physical test of the gel hand sanitizer of the ethanol extract of bay leaves (Syzygium polyanthum) with a variety of carbopol concentrations. this study used an experimental design.  Three formulations were made with different concentrations of carbopol, namely formula I (carbopol 0.5%), formula II (carbopol 1%), and formula III (carbopol 1.5%).  Of the three formulas, physical properties were evaluated which included organoleptic tests, homogeneity tests, and PH tests.  The results showed that formula I (carbopol 0.5%), and formula II (carbopol 1%) met the requirements for evaluating the physical properties of the hand sanitizer gel which included organoleptic tests, homogeneity tests, and PH tests.  While formula III (carbopol 1.5%) did not meet the physical test, namely the PH test.