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Background: Diabetes mellitus (DM) is a degenerative disease caused by damage to the pancreas in production or insulin cannot work effectively. Purslane Leaf Extract (Portulaca Oleracea) can help lower blood sugar levels. The purpose of this study was to analyze the effect of purslane leaf extract (Portulaca Oleracea) on blood sugar levels in alloxan-induced rats as a diabetes model.Methods: The rats in this study were 30 rats divided into 5 groups, each group consisting of 6 rats. The negative control group was only given aquadest and standard rat feed, while the other group was induced with 35 mg/200gBW of alloxan. The positive group was treated with standard rat diet, treatment group 1 was given purslane leaf extract at a dose of 60 mg/200grBB, treatment group 2 was given purslane leaf extract at a dose of 90 mg/200grBB and treatment group 3 was given purslane leaf extract at a dose of 110 mg/200grBW rats. Analysis of the results used the Kruskall Wallis test followed by Post Hoc Mann Whitney analysis. Results: The results of the Kruskal Wallis test on blood sugar levels showed that there was an effect after administration of purslane leaf extract among the five treatment groups p= 0.000 (p<0.05). The results of the Mann Whitney test showed that purslane leaf extract had effective antidiabetic at a dose 60 mg/200grBB p= 0.011 (p<0.05).Conclusion: Based on the results of this study, it can be concluded that purslane leaf extract can reduce blood sugar levels.    

Indonesia has a variety of plants that have potential as medicinal ingredients. One of the plants that can be used as medicine for various diseases is the parijoto plant. Parijoto is a plant that belongs to the Melastomataceae family. Parijoto plants contain flavonoid compounds, saponins, tannins and terpenoids. The content of compounds contained in the parijoto plant has various pharmacological activities. This study aims to determine the pharmacological activity of the parijoto plant (Medinilla speciosa). The method used in this study is to use the literacy review method. Reference search is done by searching Google search, Google Scholar, PubMed according to the topic. Based on a review of several literatures, it is shown that the parijoto plant (Medinilla speciosa) has pharmacological activity as antibacterial, antibiofilm, antidiabetic, antifungal, antioxidant, anticholesterol, and cytotoxic.