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Thalassemia is a chronic genetic disease that requires long-term treatment and affects children's quality of life physically, psychologically, socially, and academically due to chronic anemia and regular blood transfusion needs. This study aimed to determine factors influencing the quality of life of children with thalassemia at Rumah Sakit Anak dan Bunda Harapan Kita. A descriptive design with a cross sectional approach was used, involving 41 respondents through total sampling. Data were collected using the Pediatric Quality of Life Inventory (PedsQL 4.0 Generic Core Scale) and respondent characteristics including age, gender, socioeconomic status, parental education, and frequency of blood transfusions. Data were analyzed using univariate and bivariate analysis with the Chi-Square test. The results showed most respondents were under ten years old, female, from families with socioeconomic status below the minimum wage, had parents with high school or higher education, and received blood transfusions every three weeks. Bivariate analysis indicated only the frequency of blood transfusions was significantly associated with quality of life, while other variables were not. Thus, transfusion frequency is the main factor influencing quality of life in children with thalassemia.

Iron deficiency anemia remains a major public health problem among pregnant women in Indonesia, with a national prevalence of 37.1% and higher rates in regions such as Brebes Regency. Adequate nutritional knowledge and sufficient iron intake are expected to prevent decreases in hemoglobin (Hb) levels during the third trimester. This study aimed to analyze the relationship between nutritional knowledge, iron intake adequacy, and Hb levels among third-trimester pregnant women at Puskesmas Brebes. An analytic observational study with a cross-sectional design was conducted on 62 respondents using total sampling. Data were collected through a nutritional knowledge questionnaire, a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ) to assess iron intake based on the Recommended Dietary Allowance of 27 mg/day, and Hb measurement using a digital device. The prevalence of anemia was 32.3%, with a mean Hb level of 11.25 ± 1.74 g/dL. Most respondents had high nutritional knowledge (72.6%), but 79.0% had inadequate iron intake. Chi-Square analysis showed no significant relationship between nutritional knowledge and Hb levels (p=0.109) or between iron intake adequacy and Hb levels (p=0.426). Other factors, including iron absorption inhibitors, compliance with iron supplementation, nutritional status, and limited sample size, may have influenced the results.

This study aims to analyze the extent of the effect of honey bee pollen supplementation on increasing appetite and body weight in anemic children. The type of research used in this study is an experimental study with a pre- and post-test one-group design. The research sample consisted of 52 anemic fourth- and fifth-grade elementary school students. The average total food intake (Yellow Rice) showed a significant result (P=0.000), increasing from 241.40±94.334 g to 354.94±122.57 g after the final measurement of ad libitum appetite. The average body weight also showed a significant result (P=0.00), with a mean of 23.59±5.29 kg at pre-test and rising to 24.65±5.58 kg at post-test. The Z-Score calculation for weight-for-age based on the WHO NCHS reference showed a non-significant result: P=0.0180 (0.01±0.04) at pre-test and 0.03±0.08 at post-test. Based on the 24-hour recall analysis over two days, a significant result was obtained (P=0.000), with total energy intake of elementary school students increasing from an average of 1,594±420.17 kcal before intervention to 2,070.2±491.77 kcal after two months of intervention. After statistical testing (Paired T-Test), a P-value of 0.00 (<0.05) was obtained. It can be concluded that the administration of honey bee pollen for 8 weeks at a dose of 25 grams per day significantly increased appetite and body weight in anemic elementary school children.

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an obligate intracellular bacterium that affects the skin, peripheral nerves, upper respiratory mucosa, and eyes. Type 2 diabetes mellitus (T2DM) is a comorbidity that can worsen the course of leprosy. The female patient, Mrs. D, aged 55 years came to the emergency room of Cut Meutia Hospital with the main complaint of red bumps accompanied by pain on the face, hands, chest, and back since 3 days ago and additional complaints such as fever, joint pain, and numbness and loss of feeling in the legs, weakness, frequent thirst, and frequent urination. Dermatologic status is obtained in the facial region in the form of erythema nodules with firm boundaries with numular size, multiple. Laboratory examination showed anemia and leukocytosis. The therapy given was MDT MB package, ferrous sulfate 1x325 mg and PRC transfusion 3 kolf. Complaints arose acutely after the patient resumed taking MDT (multidrug therapy) leprosy drugs which had previously been stopped for more than 3 months. Based on the time of onset of symptoms, history of leprosy treatment, and the manifestation of systemic inflammatory lesions with signs of neurotropism, it can be suspected that the patient is experiencing a type 2 leprosy reaction or Erythema Nodosum Leprosum (ENL).

Anemia remains a significant nutritional problem among adolescent girls due to increased iron requirements during growth and menstruation. Iron (Fe) tablet supplementation is commonly used for prevention, but low compliance often limits its effectiveness. Moringa oleifera leaf tea offers a potential local food–based alternative intervention. This study aimed to compare the effectiveness of Moringa oleifera leaf tea and iron tablets in increasing hemoglobin levels among anemic adolescent girls. A quasi-experimental two-group pretest–posttest design was employed in December 2025 at two junior high schools in Gorontalo City. The sample consisted of 18 adolescent girls with mild to moderate anemia, divided equally into a Moringa leaf tea group and an iron tablet group. The tea group consumed Moringa leaf tea twice daily for 14 days, while the tablet group consumed one iron tablet per week for two weeks. Hemoglobin levels were measured before and after the intervention using a digital hemoglobin analyzer. Data analysis using the Wilcoxon signed-rank test and Mann–Whitney test showed that both interventions significantly increased hemoglobin levels. However, the increase was greater in the Moringa group (ΔHb 1.4–3.2 g/dL; p = 0.008) compared to the iron tablet group (ΔHb 0.5–0.8 g/dL; p = 0.007). A significant difference between groups (p < 0.001) indicates that Moringa oleifera leaf tea is more effective as an alternative intervention.

Smoking is the activity of smoking smoke from the burning of tobacco in cigarettes, one end of the cigarette is burned and the smoke can be smoked through the mouth on the other end. If the amount or form of hemoglobin is abnormal, red blood cells cannot function properly in transporting oxygen and carbon dioxide. This can trigger various health problems, including anemia. From the results of this study, we can see that the average value or mean value of hemoglobin levels is 12.5 g/dL, the median value is 12.9 g/dL, the minimum value is 11.9 g/dL, and the maximum value is 16.2 g/dL. The results showed that most of the respondents had hemoglobin levels within normal limits. In detail, hemoglobin levels in the normal category were 23 respondents, low category was 1 respondent, and high category was 1 respondent. This shows that the majority of active smokers in Market VI of North Binjai Village still have normal hemoglobin levels, although smoking has the potential to affect oxygen transport capacity in the long term and increase the risk of health problems if it continues continuously.

Nutritional problems in adolescents are complex, as evidenced by the high rate of iron deficiency anemia, especially among girls (23%), as well as malnutrition and overnutrition. According to SKI (2023), nutritional problems in adolescents include thinness and extreme thinness reaching 7.6%, while adolescents who are overweight reach 12.1%, and those who are obese reach 4.1%. The objectives are to determine the knowledge of balanced nutrition and eating habits of students in their daily lives and to identify the relationship between knowledge and eating habits with nutritional status. This study used a cross-sectional design with a population of 45 students from the Midwifery Study Program at Harkat Negeri University. The sampling technique used was total sampling. The research instrument was a questionnaire distributed via Google Form, while nutritional status was obtained by measuring BMI. Univariate and bivariate analyses were used. The majority of respondents were aged 20 years (44.5%), had good nutritional knowledge (59.1%), poor eating habits (63.6%), and normal nutritional status (68.2%). In the bivariate analysis, there was no significant relationship between nutritional knowledge and eating habits with the nutritional status of students (p-value >0.05). Conclusion The majority of students had good understanding of nutrition, but not of eating habits. It is hoped that students can maintain eating habits with balanced nutrition in order to achieve normal nutritional status. Keywords: Nutrition Knowledge; Eating Habits; Nutritional Status

Background: Sleep disorders in adolescents are a significant health problem, with a global prevalence reaching 57.8% and particularly high rates in several cities in Indonesia. Poor sleep quality negatively impacts physical health, such as the risk of cardiovascular disease and anemia, as well as mental and cognitive health. Sleep behavior is influenced by a dynamic interaction between personal and environmental factors, as explained in Social Cognitive Theory (SCT). Research Objective: To identify the determinants of sleep deprivation in adolescents, specifically individual and environmental factors, based on a Social Cognitive Theory (SCT) perspective through a literature review from 2019 to 2025. Method: This study utilized a literature review. To obtain research data, the authors searched for scientific articles through Google Scholar, PubMed, and ScienceDirect databases, then analyzed 10 articles that met the inclusion criteria, published between 2020 and 2025. Results: Factors significantly associated with adolescent sleep quality were identified, with individual factors being the most dominant determinant (found in 7 studies), including academic stress and smartphone addiction. Furthermore, a positive association was found with environmental factors (found in 4 studies), such as bright lighting, noise, and uncomfortable room temperature. Conclusion: Within the framework of Social Cognitive Theory, adolescent sleep quality is the result of a reciprocal interaction between personal factors (perceived stress and self-control over gadgets), the physical environment, and sleep behavior. Individual factors such as stress and nighttime gadget use reduce self-efficacy for regular sleep, which is exacerbated by an unfavorable environment.

This study aims to analyze hematocrit values ​​using a micro method with capillary blood samples in pregnant women with anemia at the Sidodadi Kisaran Barat Community Health Center. This study is a descriptive study with a cross-sectional approach involving 15 pregnant women as respondents. Data collection was carried out through hematocrit laboratory examinations and data collection of respondent characteristics. The results showed that 60% of respondents had hematocrit levels below normal values, while 40% of respondents had hematocrit levels within normal limits. Low hematocrit levels in pregnant women are influenced by several factors, including age, education level, employment status, and level of knowledge about anemia during pregnancy. This condition has the potential to increase the risk of pregnancy complications if not optimally managed. Therefore, it is recommended that health workers continue to increase educational efforts regarding anemia prevention, the importance of regular pregnancy check-ups, and encourage pregnant women to maintain a balanced nutritional consumption pattern and adequate iron intake to support maternal and fetal health.

Low Birth Weight (LBW) remains a critical global health issue that significantly contributes to neonatal morbidity and mortality, particularly in developing countries such as Indonesia. The main challenge in addressing LBW lies in its complex and multifactorial risk profile, which involves biological, social, environmental, and healthcare-related determinants. This study aims to analyze and synthesize the risk factors associated with LBW based on recent scientific literature. A literature review method was applied by searching articles from Portal Garuda, DOAJ, PubMed, and Google Scholar published between 2020 and 2025 using relevant keywords. The findings indicate that maternal age, interpregnancy interval, nutritional status, anemia, preeclampsia, infections, socioeconomic conditions, environmental exposure, and the quality of antenatal care are significant determinants of LBW. The synthesis of evidence confirms that LBW is influenced by the interaction of multiple individual and healthcare system factors rather than a single cause. In conclusion, this study highlights the urgent need to strengthen antenatal care services, improve maternal nutritional status, control maternal diseases during pregnancy, and implement community-based promotive and preventive strategies as key efforts to reduce the incidence of LBW.

Abortion remains a complex reproductive health issue due to the interplay of multiple interrelated determinants. This study aimed to map the factors influencing the incidence of abortion based on recent scientific evidence. A literature review design was applied by analyzing ten selected articles published within the last five years and retrieved from major scientific databases. The selection process was conducted systematically through title, abstract, and full-text screening based on predefined inclusion criteria. The extracted data included study characteristics, type of abortion, examined determinants, and key conclusions. The synthesized findings indicate that abortion incidence is shaped by a combination of biological, social, and healthcare system related factors. Clinical determinants such as maternal age, endocrine disorders, uterine anatomical abnormalities, obstetric history, anemia, and hypertension play a substantial role in spontaneous and recurrent miscarriage. In contrast, structural factors including income level, contraceptive access, and legal regulations predominantly influence induced abortion. The discussion highlights that abortion should not be viewed as an isolated clinical event, but rather as the cumulative outcome of risks operating across multiple levels of influence. In conclusion, abortion represents a multifactorial phenomenon that requires comprehensive prevention strategies extending beyond medical interventions alone. These strategies should also address healthcare accessibility and broader social conditions. This review contributes to a deeper understanding of the complexity of abortion determinants and provides an evidence-based reference for developing more effective preventive approaches in the future.

Angka kematian ibu (AKI) di Indonesia masih tinggi, salah satunya dipicu oleh komplikasi kehamilan akibat kekurangan gizi. Rendahnya literasi nutrisi pada ibu hamil berkontribusi terhadap meningkatnya risiko preeklamsia, anemia, dan bayi berat lahir rendah. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan literasi nutrisi ibu hamil melalui pendampingan berbasis media kalender makanan sebagai alat bantu edukasi sederhana dan aplikatif. Pengabdian dilaksanakan di Kantor Desa Bungaejaya, Kabupaten Gowa, Sulawesi Selatan, dengan melibatkan 10 orang ibu hamil. Kegiatan ini juga dihadiri oleh kepala desa, bidan desa, kader kesehatan, dan mitra Dompet Dhuafa. Metode kegiatan mencakup penyuluhan nutrisi kehamilan, pelatihan penggunaan kalender makanan. Hasil pengabdian menunjukkan adanya peningkatan pemahaman ibu hamil mengenai kebutuhan gizi selama kehamilan. Hasil kegiatan menunjukkan bahwa edukasi visual berbasis komunitas efektif dalam meningkatkan kesadaran nutrisi pada ibu hamil serta meningkatkan kemampuan ibu dalam mengidentifikasi nutrisi tepat sehari-hari selama hamil.

Adolescents are a vulnerable age group to nutritional problems due to increased nutritional requirements during periods of rapid growth. Suboptimal nutritional status, including undernutrition and anaemia, can negatively affect health and academic performance. This study aimed to describe the nutritional status of adolescents at SMA Negeri 2 Kendari, Southeast Sulawesi Province. This study employed a descriptive observational design conducted from August to September 2025 with a total sample of 226 twelfth-grade students’ selected using proportionate stratified random sampling. Data were collected through measurements of body weight and height to determine nutritional status based on the BMI-for-Age indicator and haemoglobin levels were assessed using a digital haemometer. Data were analyzed using univariate analysis. The results showed that most respondents had normal nutritional status (52.2%), while a considerable proportion were undernutrition (47.8%). In addition, more than half of the respondents were anaemia (50.9%). These findings indicate that although anthropometric nutritional status was generally normal, anemia remains a health problem that requires attention among adolescents. Regular monitoring of nutritional status and hemoglobin levels accompanied by nutrition education is recommended. Further studies are recommended to use an analytical study design to identify factors associated with nutritional status and anaemia.

Anemia during pregnancy is a significant maternal health issue with serious impacts on maternal and perinatal outcomes, including complications such as severe preeclampsia, postpartum hemorrhage, and low birth weight (LBW), all of which contribute to increased morbidity and mortality rates. This literature review aims to analyze the clinical impacts of pregnancy anemia, related complications, and effective management strategies based on the latest scientific evidence (2020-2024). The study examines the relationship between anemia and preeclampsia, LBW, and postpartum hemorrhage, as well as the importance of nutritional fulfillment in prevention and management. Five research articles from indexed journals were collected from the Scopus database, with inclusion criteria of studies with clear designs, focusing on pregnancy anemia, and published in Indonesian or English. The analysis results show that pregnancy anemia is a predisposing factor for preeclampsia through mechanisms such as placental hypoxia and oxidative stress. Anemia is also closely related to an increased incidence of LBW and postpartum hemorrhage, particularly due to lower hemoglobin reserves and uterine contractility issues. Adequate nutritional fulfillment is influenced by socioeconomic barriers, supplementation side effects, and lack of family support. Anemia management requires a comprehensive approach, including routine screening, prophylactic supplementation, nutritional education, and effective referral systems for complex cases. Prevention through early detection and timely intervention is crucial in reducing maternal and perinatal morbidity.

Red blood cells are essential for carrying oxygen and vital nutrients needed for the growth of the fetus, therefore anemia during pregnancy is a complex issue. It is vital for all expectant mothers to fulfill their iron needs because maternal anemia during pregnancy can result in adverse consequences for the child, such as premature birth and low birth weight. The chance of a woman developing anemia increases as she ages during pregnancy. Bleeding is a direct result of the anemia experienced during labor in 17.24% of cases. The purpose of this study was to determine the connection between the incidence of anemia and young pregnant women in Ir. Soekarno Hospital on Morotai Island. The study used an analytical survey with a cross-sectional approach, which is useful for finding relationships between two or more variables. The whole sampling technique, which included 40 participants in all, was used. A checklist was used as the study's instrument. Chi-Square analysis was used to analyze the collected data using SPSS software. The chi-square statistical analysis produced a P-value (asymp. The p-value (2-tailed) is 0.002, which is less than the 0.05 significance level. This indicates a relationship between the start of anemia and young pregnant women. Thus, it is possible to infer a link between the incidence of anemia and young pregnant women, leading to the rejection of H0 and the endorsement of H1.

Iron deficiency anemia is a significant public health problem in pregnant women, because it can cause maternal and fetal complications. Compliance with iron tablet consumption is often low due to limited knowledge, side effects, and cultural misconceptions. Leaflet-based education is a low-cost intervention that has the potential to improve understanding and compliance. This study aims to analyze the effect of leaflet education on the adherence of iron tablet consumption in pregnant women at the Pujon Health Center, Batu. The research design used a quasi-experiment with a pretest-posttest control group design. A total of 40 pregnant women were divided into an intervention group (n = 20) that received leaflet education and a control group (n = 20) that received standard counseling. Compliance was measured over four weeks through self-consumption records and tablet count calculations, while knowledge was assessed with a structured questionnaire. Data analysis used the Chi-square test with a significance level of p < 0.05. Results showed a significant improvement in adherence in the intervention group, with 70% of pregnant women complying compared to 15% in the control group (p = 0.001). Leaflet education also increased knowledge scores and consistency of iron tablet consumption. The conclusion of this study confirms that leaflet education is effective in increasing iron supplementation adherence, so it is recommended to be integrated into routine antenatal services to prevent anemia and support maternal and fetal health.

Background: Anemia is one of the public health problems commonly found among adolescent girls, especially in developing countries like Indonesia. This condition affects concentration, academic performance, and productivity, making early detection an essential step to prevent long-term complications. Objective: This study aims to determine the results of early detection of anemia based on clinical symptoms and hemoglobin (Hb) levels among adolescent girls at SMPN 18 Palembang. Methods: This research used a descriptive design with a cross-sectional approach. A total of 132 seventh-grade female students were selected randomly. Data were collected through an anemia symptom questionnaire and hemoglobin level measurement using a hemoglobinometer. Results: The study found that 23.5% of respondents were anemic (Hb < 12 g/dL), and 48.5% showed symptoms of anemia. However, the sensitivity of symptoms in detecting anemia was only 39%, specificity was 19%, with a positive predictive value (PPV) of 60.93% and a negative predictive value (NPV) of 8.82%. Conclusion: Based on the findings, symptom-based detection alone is not sufficiently accurate to diagnose anemia. Hemoglobin level examination is still required as a more valid and objective screening method for the early detection of anemia in adolescent girls In addition to medical intervention, the study advocates for increased awareness and education about anemia, its causes, and prevention methods among students, parents, and educators. Addressing nutritional deficiencies, especially iron intake, through dietary improvements and supplementation is essential in combating anemia in adolescent girls.

Maternal mortality remains a challenge in Indonesia, and one contributing factor is chronic malnutrition (CED), which impacts pregnancy, childbirth, the postpartum period, and the newborn. The 2022 registration report shows that of the 3,249,203 pregnant women whose MUAC was measured, 283,833 had a MUAC of less than 23.5 cm (at risk of CED), meaning 8.7% of these pregnant women were at risk of CED. In the Brebes area, the 2022 report recorded 3,475 pregnant women with CED. At the Bantarkawung Community Health Center in 2023, there were 36 cases of preeclampsia, 22 cases of transverse lie, 107 cases of CED, and anemia. Objective: Provide comprehensive midwifery care in accordance with standards of care for pregnant women, women giving birth, newborns, postpartum women, and family planning. Research method: Qualitative descriptive method, the type of research approach used in this study is a comprehensive case study approach. Results: Comprehensive care was provided to Mrs. R who suffered from chronic energy deficiency, and was successfully overcome. Delivery was carried out by caesarean section, the baby was born normally, and the postpartum period went smoothly, and the mother chose a contraceptive method, namely a three-monthly birth control injection. Conclusion: Comprehensive obstetric care has been proven effective in overcoming chronic energy deficiency, ensuring a safe delivery, a normal baby born, a normal postpartum period, and compliance with contraceptive methods.

The pregnancy period is a crucial time for ensuring the health of the mother and fetus through the provision of balanced nutrition. However, nutritional issues such as anemia and chronic energy deficiency (CED) are still commonly found among pregnant women. The use of local nutritious foods, such as moringa leaves (Moringa oleifera), can be a potential solution to support nutritional needs. This community service activity aims to improve the knowledge and skills of pregnant women in preparing healthy menus and balanced eating patterns using moringa leaves. The activity was carried out through interactive lectures, coaching on menu preparation, cooking demonstrations of moringa leaf dishes, and evaluation through pre-tests and post-tests. The participants were pregnant women in the working area of the Wara Selatan Health Center in Palopo City, totaling 25 people. The results showed an increase in participants' nutritional knowledge, with an average pre-test score of 55 rising to 82 in the post-test. Participants were also able to prepare a balanced daily menu based on moringa leaves and produce several processed products, including moringa soup, moringa fritters, and moringa pudding. It can be concluded that the healthy menu coaching activity using local moringa leaves effectively improves the knowledge and skills of pregnant women regarding balanced nutrition. The use of local foods such as moringa leaves has the potential to support the improvement of maternal nutritional status in a simple, economical, and sustainable manner.

Pregnancy is a unique natural condition because although it is not a disease, it often causes complications due to various anatomical and physiological changes in the mother's body. Pregnant women who suffer from anemia can have an impact on the fetus, such as premature birth, the risk of low birth weight (LBW), fetal abnormalities, and increased risk of fetal distress. In general, the causes of anemia in pregnancy are iron deficiency and acute bleeding or even the interaction of both. The purpose of this study was to determine the difference in the effectiveness of giving red spinach juice and Ambon bananas on Hb levels in pregnant women in the third trimester. The design used in this study was a quantitative inferential study including the pre-experimental type with two group pretest-posttest. Based on the time of data collection, it included the cross-sectional type, sourced from primary and secondary data. An assessment of the difference in increasing HB levels was carried out before and after treatment (Pretest and Postest two Group Design). Data analysis consisted of univariate and bivariate analysis. The results of the analysis showed an effect in giving red spinach juice and Ambon bananas. It is hoped that the Health Center will facilitate health workers (midwives) in providing information on providing guava juice with red spinach leaf juice as an alternative for preventing and managing anemia during pregnancy in the Health Center's work area.