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The development of modern biotechnology has brought fundamental changes to the life sciences through the application of molecular biology, genetic engineering, and bioinformatics techniques. This article aims to examine the transformation of life sciences through modern biotechnology approaches and its impact on health, agriculture, the environment, and industry. The method used is a descriptive-analytical literature review based on international journal sources and relevant scientific publications. The results of the study indicate that technologies such as CRISPR-Cas9 enable precise gene editing for genetic disease therapy, while the mRNA vaccine platforms developed by Pfizer and Moderna demonstrate the acceleration of biomedical innovation in response to the global pandemic. In the agricultural sector, genetic engineering increases crop productivity and resilience, while in the environmental sector, biotechnology supports environmentally friendly bioremediation processes. However, ethical and regulatory challenges remain important concerns in its implementation. In conclusion, modern biotechnology plays a key role as a catalyst for sustainable, innovation-driven transformation in the life sciences.

Processing plastic waste into fuel oil with pyrolysis technology. Research on plastic oil as an alternative fuel has been widely conducted. One of them is research on processing plastic bag waste into fuel oil with pyrolysis technology. In this study, a set of pyrolysis equipment was made by Lecturers and Students of UMNU Kebumen. The plastic waste used in this study was 1 kg of plastic bag. Meanwhile, the pyrolysis process used a temperature of 250oC-300oC. The fuel oil produced in the pyrolysis process of this study was approximately 400 ml. The average density of fuel oil from plastic bag waste was 0.733 gr/ml. The results of this density calculation are in the possibility of the density of gasoline, namely 0.710 gr/ml to 0.770 gr/ml. This pyrolysis process shows great potential for converting plastic waste into an environmentally friendly alternative energy source. Furthermore, the efficiency of this pyrolysis technology can be improved by adjusting the temperature and processing time, as well as by selecting a wider variety of plastic types. This technology has the potential to be applied more widely in plastic waste management within the community as a solution to reduce environmental pollution while generating renewable energy.

The discharge of surfactant-laden wastewater from the rapidly expanding laundry industry poses significant environmental risks, especially in densely populated urban areas. While constructed wetlands (CWs) and Eco-Enzyme technology have shown promise for surfactant remediation, their standalone application requires long hydraulic retention times (HRTs), limiting practical implementation. This study evaluated the efficacy of a novel integrated system combining a subsurface constructed wetland (SSFCW) with fruit peel-derived Eco-Enzyme to treat synthetic laundry wastewater. Over a 6-day treatment period, the combined system achieved a remarkable surfactant removal efficiency of 99.63%, reducing the concentration from 225 mg/L to 0.835 mg/L—well below the regulatory threshold of 3 mg/L. The synergistic degradation mechanism involves enzymatic hydrolysis via Eco-Enzyme lipase and protease activity, complemented by microbial mineralization in the wetland rhizosphere. This system maintains optimal environmental conditions, with a stable pH of 6.85-7.32 and a temperature of 30.9-35.2°C, supporting robust biological activity. These findings demonstrate that the integrated Eco-Enzyme/SSFCW system overcomes the limitations of conventional HRT approaches, offering a highly efficient, sustainable, and practical decentralized wastewater treatment solution for the laundry industry.  

That Christian Religious Education teachers update their professionalism and competencies to ensure that Christian education remains relevant, effective, and transformative. This study aims to analyze the modernization of the professionalism of Christian Religious Education teachers, including the integration of spirituality with modern pedagogical approaches and strategies for developing teacher competencies in addressing the challenges of the digital generation. The study employs a descriptive qualitative approach, collecting data through literature review from books, journals, notes, and relevant reports, and presenting the findings in a narrative form. The results show that the modernization of teacher competencies involves the development of pedagogical, personal, social, spiritual, and professional competencies, with the ability to integrate spirituality, technology, and modern teaching methods such as collaborative and digital learning to create contextual, engaging, and transformative learning experiences. In conclusion, the modernization of professionalism among Christian Religious Education teachers is an urgent necessity to enable teachers to deliver God’s Word in a relevant manner, shape students’ character and spirituality, and enhance the effectiveness of Christian education through mastery of holistic and collaborative competencies.  

The era of globalization demands that education systems produce human resources who are skilled, adaptable, and capable of competing in the international job market. However, several issues arise in efforts to prepare graduates who are well aligned with industry requirements. These challenges include the mismatch between competencies taught in educational institutions and those required by the workforce, limited digital literacy and technological mastery, the lack of soft skills development, and insufficient collaboration between schools and industries. Rapid technological advancements often result in curricula that lag behind the current skill demands of the labor market. Moreover, many students still lack the mindset, creativity, and adaptability needed to face global competition. This literature-based study aims to identify the main educational problems in preparing human resources for the world of work and propose strategic directions for improvement. Findings highlight the necessity of competency-based curriculum transformation, enhanced vocational training, integration of technology-based learning, and stronger partnerships between education providers and industry sectors. Enhancing teacher quality is also crucial to ensure learning processes remain relevant to global demands. By optimizing the roles of all stakeholders, education can produce graduates who possess not only technical expertise but also essential 21st-century skills such as communication, collaboration, problem-solving, and leadership. Therefore, education becomes the primary foundation for preparing a generation capable of competing globally and contributing to national development.

The development of science and technology has encouraged the utilization of graph theory in solving optimization problems, particularly in transportation systems and tourism route planning. Medan City, as a metropolitan area with dense road networks and widely dispersed tourist destinations, faces challenges in selecting efficient travel routes. This research aims to determine the optimal route between tourist destinations in Medan City using the Minimum Spanning Tree (MST) method with Prim’s Algorithm. The research was conducted using a weighted graph modeling approach, where each tourist destination is represented as a vertex and the distance between destinations is represented as an edge weight. Distance data and estimated travel time were obtained through digital mapping using Google Maps and then analyzed through iterations of Prim’s Algorithm to produce a minimum spanning tree without forming cycles. The results show that all 23 tourist destinations are successfully connected in a single MST structure with a minimum total distance of 68.97 km and a travel time of approximately 199 minutes or 3 hours and 19 minutes. This model is expected to serve as a reference for tourism planning and support urban transportation efficiency based on mathematical computation.

The rapid advancement of digital technology has significantly transformed the economic landscape, particularly in payment systems that are shifting from conventional cash transactions to the use of Electronic Money (E-Money). E-Money has become increasingly popular due to the convenience it offers, allowing users to conduct transactions anytime and anywhere without the need to carry physical cash. As this payment innovation continues to expand, it is essential to examine whether its mechanisms comply with Islamic principles, given that the use of E-Money is closely related to the values of muamalah in Islam. This study aims to identify the underlying contractual structure (akad) governing Mandiri E-Money transactions and to assess its conformity with sharia principles. It further analyzes the potential presence of gharar, riba, or maisir within the top-up and transaction processes, as well as the sharia mitigation mechanisms that may be applied. The research employs a normative approach based on classical and contemporary Islamic legal theory, supported by observational analysis of Mandiri E-Money practices. Data were analyzed qualitatively using a descriptive method and maqashid al-shariah reasoning. The findings indicate that the use of Mandiri E-Money does not involve elements of riba, gharar, or maisir, and therefore does not deviate from sharia principles. These potential risks were examined through fiqh legal maxims and DSN-MUI fatwas to ensure comprehensive sharia compliance.

The purpose of this study was to evaluate the application of the Deep Learning approach in teaching mathematics in the first grade of addition and subtraction of numbers 1 to 20 in a story problem through the concrete media Si PONPEL and the educational game Quizizz Paper Mode. This technology-based learning is intended to make learning more interactive and enjoyable, but does not require personal digital devices. Qualitative and quantitative data were collected through a mixed-method research design to measure student understanding the result show that the Si PONPEL and Quizizz Paper Mode methods successfully improved students’ understanding of basic mathematical concepts, with an average increase in student scores of 38.33%. In addition, findings from interviews conducted with teachers and students showed that the Si PONPEL concrete media and this technology made students more engaged and motivated to learn. It is hoped that this research will make a significant contribution to creating more inclusive and interactive mathematics kearning in elementary schools.

Village entrepreneurship is an initiative designed to stimulate regional economic growth by accelerating the development of rural areas, which have long been perceived as slow, less productive, and lagging behind urban centers. The creation of entrepreneurial villages offers a concrete strategy to enhance community productivity because it encourages all components of the village government, residents, and local institutions to participate in structured and collaborative entrepreneurial activities. Such villages are expected to generate new economic opportunities, strengthen local industries, and increase community independence. However, initial observations from this Community Service program show that partner villages still face significant barriers, including limited land area, geographical remoteness, and inadequate human and natural resources. Many peripheral villages have not yet utilized digital technology effectively, making it difficult to expand markets or access broader economic networks. In addition, challenges related to financial access, limited talent development, socio-cultural constraints, and weak market infrastructure continue to hinder economic progress. These conditions demonstrate the urgent need for strategic assistance, capacity-building programs, and stronger support systems to help villages transform into sustainable entrepreneurial ecosystems capable of contributing to long-term regional development.

The development of digital technology requires villages to transform not only their governance but also their public awareness of digital opportunities and risks. However, the process of digital transformation cannot be separated from the local socio-cultural context. This Community Service (PKM) activity aims to strengthen local wisdom-based transformational leadership as a strategy for dealing with digital dynamics in Pesanggrahan Village, Kutorejo District, Mojokerto Regency. The implementation methods included a situation analysis, program socialization, digital literacy seminars, discussions on Pancasila values, and mentoring for village officials, community leaders, religious leaders, and Karang Taruna youth. The activity results showed an increase in participants' understanding of digital literacy, media ethics, and the relevance of local values, such as cooperation, deliberation, and tolerance, in supporting the village's digital transformation. The community also showed enthusiasm for participating in the development of digital content and technology-based services. This PKM concluded that effective digital transformation requires adaptive, character-based leadership rooted in local cultural values. Collaboration between universities, village governments, and communities is an essential prerequisite for promoting inclusive and sustainable social change.

The community service program in Purworejo Village, Sragi District, Pekalongan Regency, was implemented to enhance the capacity of local MSME actors in utilizing digital technology as a modern marketing tool. The program adopted a participatory approach involving youth organizations, business actors, village authorities, and the implementation team in every stage of the activity. Assistance included field observation, data collection, content development training, and the creation of a dedicated MSME website as a shared promotional platform. The results indicate significant social changes within the community, including improved digital literacy, stronger awareness of the importance of technology-based marketing, the emergence of local youth as digital facilitators, and the development of collaborative working patterns in managing digital media. These findings reinforce that participatory-based mentoring can strengthen community capacity in adopting technology, consistent with theoretical perspectives that position the community as key agents of local development. Therefore, the program not only produced a functional digital product in the form of an MSME website but also laid the foundation for a more adaptive, competitive, and sustainable village economic ecosystem..

This study examines the effectiveness of digital storytelling in enhancing the speaking skills of secondary EFL learners. The research responds to persistent challenges in speaking instruction, particularly students’ limited fluency, low confidence, and insufficient exposure to meaningful communicative tasks. Using a mixed methods design, the study involved an eight week intervention in which students created scripted digital stories through narration, multimedia editing, and collaborative production. Quantitative data were collected through pre-test and post-test assessments measuring fluency, pronunciation, vocabulary, and coherence, while qualitative data were obtained through observations, interviews, and student reflections. The findings reveal substantial improvements in speaking performance, especially in fluency and coherence, accompanied by increased engagement, reduced speaking anxiety, and heightened self awareness during the storytelling process. These results highlight that digital storytelling provides repeated oral practice and authentic communicative opportunities that support learners’ linguistic and affective development. The study offers implications for English teachers and curriculum designers by demonstrating that technology supported narrative tasks can be integrated into regular instruction to foster more interactive, creative, and student centered speaking learning environments.

Motorcycle theft remains a widespread issue that demands improved security solutions supported by modern technology.This research discusses the development and implementation of a motorcycle security system design using an ESP8266 microcontroller integrated incorporating the GPS Neo-7M positioning module, SW-420 vibration detection sensor, and an electronically controlled solenoid lock. The  implemented mechanism is monitored and controlled via the Telegram application, allowing the owner to receive real-time updates about the motorcycle’s status through a Telegram Bot. The development process involves hardware integration, ESP8266 programming, and functional testing. The SW-420 sensor detects vibrations as indicators of possible theft, triggering a buzzer alarm and sending instant notifications through Telegram. The GPS Neo-7M module provides location data in real time, automatically or upon user request, through a Google Maps link. Users can also lock or unlock the motorcycle remotely by sending the lock or /unlock commands via Telegram. Test results show that the system responds to vibrations in less than one second, delivers Telegram notifications within 3–5 seconds, and determines location with an accuracy of 3–10 meters. Overall, the proposed system offers an effective, practical, and low-cost solution to enhance motorcycle security.

In the era of digital transformation, modern, systematic, and integrated archive management has become a crucial element in creating effective, efficient, and accountable education governance. Office Management and Business Services (MPLB) teachers in East Java still face obstacles in implementing technology-based archive management due to limited digital literacy, lack of supporting facilities, and minimal ongoing training relevant to 21st-century needs. This Community Service (PKM) activity aims to improve the professional competence of MPLB teachers in modern archive management through interactive workshop-based training, intensive mentoring, and direct simulation of the use of digital archiving applications. The implementation methods included participant needs analysis, problem-solving-based module development, digital archive management practice using a cloud system, and pre-test and post-test-based evaluation to measure competency improvement. The results of the activity showed an average increase in participant understanding of 42%, a 58% increase in operational skills in using archiving applications, and a 35% increase in archive management time efficiency. In addition, teachers are able to implement an electronic file classification system in schools and build a database of digitized documents. These activities strengthen transparent and sustainable educational administration, as well as supporting the realization of inclusive and globally competitive education in line with the Asta Cita vision towards Indonesia Emas 2030.

This meta-synthesis examines in depth the effectiveness of technology-assisted therapy (TAT) in the treatment of war-related trauma through a systematic analysis of 47 empirical studies with a total of 6,842 participants published between 2010 and 2024. The quantitative synthesis indicates that the implementation of TAT demonstrates statistically significant effectiveness in reducing the severity of post-traumatic stress disorder symptoms (d=0.78, 95% CI [0.65, 0.91]), anxiety (d=0.69, 95% CI [0.54, 0.84]), and depression (d=0.72, 95% CI [0.58, 0.86]) among populations affected by armed conflict. Among the various digital modalities, Virtual Reality Exposure Therapy (VRET) exhibits the strongest therapeutic effect (d=0.85) compared with mobile-based intervention (d=0.71) and teletherapy (d=0.68). Further moderator analysis identifies the optimal intervention duration as 12 to 16 weeks, with a significant effect contribution (β=0.34, p<.001) and a relatively moderate dropout rate of 18.7%. These findings extend Tng et al. (2024) by confirming the superiority of VRET and by confirming the significance of therapist support for the effectiveness of TAT (Wu et al., 2025). In contrast to the meta-analysis by Eshuis et al. (2021), which emphasized a single approach, this study reveals that hybrid interventions that integrate multiple digital platforms simultaneously (d=0.89) are superior to single-platform interventions (d=0.67). Overall, the results of this meta-synthesis provide a strong empirical foundation for the development of more comprehensive, adaptive, and contextually relevant TAT protocols for war-related trauma.

The development of digital technology and the Internet of Things (IoT) has transformed the paradigm of urban development towards the concept of a smart city based on data and connectivity. This study analyzes the nature of smart cities through three dimensions of the philosophy of science: ontology, epistemology, and axiology. From an ontological perspective, a smart city is understood as a complex entity consisting of physical, digital, social, and ecological systems that interact with each other to create efficient and adaptive urban governance. Epistemologically, knowledge in a smart city is obtained through the process of collecting, processing, and analyzing data from various IoT devices, sensors, and citizen participation, thereby producing new insights that support evidence-based decision-making (data-driven governance). From an axiological perspective, a smart city has ethical values and goals to improve the quality of life of its citizens, strengthen government transparency, maintain environmental sustainability, and promote inclusive social participation. Thus, this study asserts that the development of a smart city is not only technological but also has a philosophical foundation oriented towards a balance between efficiency, humanity, and sustainability.

Digital transformation has become an essential approach for MSMEs to improve their operational efficiency and market competitiveness. This research investigates the acceptance of electronic payment systems among MSMEs using the Technology Acceptance Model (TAM). Data were obtained through questionnaires distributed to MSME respondents and analyzed using the bootstrapping technique to evaluate the significance of variable relationships. The findings reveal that Perceived Ease of Use (PEOU) has a significant impact on both Perceived Usefulness (PU) and Attitude Toward Using (ATU). Moreover, PU and ATU exert positive influences on Behavioral Intention (BI), with R² values of 0.65 for ATU and 0.71 for BI. These results suggest that the perceived ease of use and usefulness of electronic payment systems play a crucial role in shaping MSMEs’ attitudes and intentions toward adopting digital technologies. This study offers insights for formulating effective digital transformation strategies for MSMEs through the implementation of electronic payment systems.

This study explores the intersection of Artificial Intelligence (AI), agriculture, and decolonial philosophy, emphasizing the role of local knowledge as the foundation for sustainable agricultural technology in Indonesia. The research investigates how AI can be developed not as a tool of technological domination but as a dialogical partner that recognizes the epistemic value of indigenous wisdom. Using a mixed-method approach, the study combines algorithmic experiments applying lightweight Convolutional Neural Networks (CNN) with Explainable AI (XAI) methods such as SHAP and LIME with participatory interviews involving farmers in Bima District. Empirical findings show that models integrated with localized visualization and community-based interpretability improved user trust by 84% and reduced computational energy by 28% without compromising accuracy. More importantly, the interaction between AI and farmers revealed a form of epistemic integration where algorithmic logic aligns with traditional indicators, such as soil texture, humidity, and seasonal signs known to local farmers. Philosophically, this research asserts that sustainable AI should emerge from ecological and cultural contexts rather than imposing external frameworks. In the decolonial sense, it positions local farmers not as passive users but as active epistemic agents shaping the meaning of technology. Thus, AI becomes not only a technical instrument but a site of ethical and epistemic liberation that reaffirms human responsibility toward knowledge, culture, and the earth.

This study aims to examine the effectiveness of implementing a descriptive writing learning model based on digital literacy and local wisdom in improving writing skills, learning motivation, and cultural character among junior high school students. Employing a descriptive qualitative approach with a case study design, the research was conducted at SMP Negeri 2 Kroya, Cilacap Regency, during the 2025–2026 academic year. Data were collected through participatory observation, in-depth interviews, and document analysis, and were subsequently analyzed using the interactive model developed by Miles, Huberman, and Saldaña. The findings indicate that the application of this model effectively enhances students’ writing abilities in terms of content, structure, language style, and digital literacy ethics. The integration of digital technology fosters the development of cognitive, technical, and social literacy, while the reinforcement of local wisdom cultivates cultural awareness, regional identity pride, and reflective thinking skills. Writing activities evolved into collaborative and creative processes that combine cultural exploration with the ethical use of digital technology. From a pedagogical perspective, this model aligns with the principles of deep learning promoted by the Kurikulum Merdeka and contributes to strengthening the Eight Dimensions of Graduate Competencies, particularly in critical reasoning and problem-solving, creativity and innovation, collaboration and mutual cooperation, as well as the development of the Pancasila student profile and global citizenship. Therefore, the descriptive writing learning model based on digital literacy and local wisdom can be regarded as an innovative strategy in Indonesian language education to realize a contextual, reflective, creative, and culturally grounded learning process.

The advancement of information technology has brought significant changes to society but also generated new crimes, such as online child sexual exploitation (cybersex trafficking). This study examines this phenomenon by focusing on the live streaming application "HOT51," which is frequently used as a medium for child exploitation. The research employs a qualitative descriptive analysis method based on secondary data from official reports and related literature. Findings indicate that the easy access to modified APK applications facilitates sexual exploitation of children, the most vulnerable group. Indonesian regulations already address child protection, but implementation faces challenges such as low digital literacy and weak supervision of digital platforms. This study emphasizes the need for tightened monitoring, digital literacy education, and active parental roles to reduce the risk of sexual exploitation in the digital realm. The contribution lies in enhancing understanding of child protection challenges in the digital era and highlighting the importance of adaptive regulations and multi-stakeholder cooperation to safeguard child rights and safety.