Publication Search

Immunization is one of the most effective and efficient public health efforts in preventing diseases and reducing mortality rates in children such as smallpox, polio, tuberculosis, hepatitis B, diphtheria, measles, rubella, congenital rubella syndrome (CRS), tetanus, pneumonia (lung inflammation) and meningitis (inflammation of the brain membrane) (Nandi & Shet, 2020). Data from the Indonesian Ministry of Health in 2020 showed that vaccination coverage in the 3rd and 4th months was months. However, efforts can be made to increase child vaccination coverage to 80% and that does not include DT, MR2, and HPV vaccinations. As, measles data is only 45%, diphtheria-tetanus (DT) is around 40% (Indonesian Ministry of Health, 2021). To determine the relationship between maternal knowledge and the completeness of basic immunization in children at the Raden Omas Posyandu. This study uses a quantitative research design with a cross-sectional method. The population in this study consisted of mothers who had children aged 12 to 18 months at Posyandu Raden Omas, totaling 36 mothers. The statistical results showed a relationship between maternal knowledge and the completeness of basic immunization in children p-value (0.048). Most respondents had good knowledge, as many as 13 respondents (36.1%). Sufficient knowledge, as many as 13 respondents (36.1%). Insufficient knowledge, as many as 10 respondents or 27.8%. Most respondents had incomplete immunization, namely 18 respondents (50%).

The high risk of zoonotic disease transmission in cattle farming environments necessitates effective education to enhance workers' understanding and hygienic behaviors. This study aims to improve workers' awareness and hygienic practices in preventing zoonotic diseases through an outreach program at Manonjaya Farm. The method used is a case study with a qualitative approach, involving semi-structured interviews and direct observation. The educational activities were conducted interactively using posters, lectures, and demonstrations of the six-step Handwashing with Soap (CTPS) technique. The results indicate an increase in workers' understanding of zoonotic risks, particularly bovine tuberculosis, as well as the importance of maintaining barn cleanliness, regular vaccinations, and the use of personal protective equipment. Furthermore, the CTPS practice successfully enhanced workers’ skills and consistency in implementing hygienic behaviors. Supporting strategies such as the installation of educational posters, distribution of vaccination logbooks, and provision of handwashing soap contributed to the sustainability of behavioral changes. These findings affirm the effectiveness of interactive lectures and demonstrations in improving knowledge and preventive measures against zoonotic diseases within farming communities, aligning with the One Health approach.

iNKT cells, sometimes known as the immune system's "Swiss Army knife," have become key components of cancer vaccination treatments. Glycolipids that activate iNKT cells, including α-galactosylceramide (αGalCer), have been used to create self-adjuvanting anti-tumor vaccinations and can boost the immune response to co-delivered cancer antigens. The chemicals synthesis of ganglioside antigens, specifically (Neu5Gc) GM3 and GM3 antigen, and conjugations to αGalCer, and packaging into liposome as effective platforms for their in vivo deliverying are the main topics of this work. In mouse and human cell experiments, liposome containing, (Neu5Gc) GM3-αGalCer, GM3-αGalCer, and equimolar quantities of conjugates have thoroughly described and their capacities to activate iNKT cell has verified ex vivo. All subclasses of IgG antibodies were produced as a result of the candidates' potential to generate both TH1 and TH2 cytokines, according to in vivo immunization tests. Interestingly, this study shows serum antibody produced against the TACA were cross-reactive, both when they were produced separately and together. If tumor-selective antigens is selected, the ensuing antibodies response can be wider than expected, which has implications for future vaccine formulations.

The COVID-19 vaccination program is a new program initiated by the government to create herd immunity for COVID-19 with a target target of 70% of the population. Vaccination turns out to provide its own anxiety for the community. Anxiety occurs during the Covid-19 pandemic and is also felt when there is a vaccination program in the community. To find out the relationship between the vaccination program and the level of anxiety in the community during the Covid-19 pandemic in the Rt. 02 Bojong Baru Village, Bogor Regency in 2021. The type of research used is descriptive correlation research using a cross sectional study approach. Based on the results of the Spearman rank test, there is a correlation or relationship between the administration of the vaccination program and the level in the Rt.

This study evaluates the effectiveness of vaccination programs in reducing the incidence of infectious diseases in low-income countries. By analyzing immunization coverage data and disease prevalence rates, the research highlights the successes and challenges faced by vaccination initiatives. The findings indicate that comprehensive vaccination campaigns significantly decrease morbidity and mortality rates, emphasizing the need for sustained investment and community engagement to improve public health outcomes.

This article assesses the effectiveness of vaccination campaigns in controlling the spread of infectious diseases, focusing on recent outbreaks of measles and influenza. Through a comparative analysis of vaccination rates and disease incidence in different regions, the study identifies key factors contributing to successful vaccination efforts. The findings emphasize the importance of public awareness and accessibility in achieving high vaccination coverage to prevent outbreaks.

Background: Cervical cancer is the fourth most common disease of the female reproductive system worldwide. The incidence of cervical cancer in the world is entering a critical period, where every year the incidence of cervical cancer is increasing. Until now, cervical cancer is the leading cause of death in developing countries. Aim: To find out about women's knowledge and attitudes towards cervical cancer. Method: Scoping review using Arksey and O'Malley frameworks, using databases from PubMed, EBSCO and Wiley. Result: A total of 14 articles from 2016-2021 used critical appraisal from JBI (Joanna Briggs Institute). Women's knowledge and attitudes towards cervical cancer have six themes. The first theme is knowledge about cervical cancer which consists of knowledge about risk factors, signs and symptoms and early detection of cervical cancer. The second theme is the attitude of women towards cervical cancer consisting of positive and negative attitudes. The third theme is the factors that influence knowledge consisting of age, education, family income and sexual frequency. The fourth theme of factors that influence attitudes is age and education. The fifth theme of information sources consists of mass media, family and friends, health workers and health services. Theme six is the barriers to accessing information and services consisting of a lack of awareness and the high cost of vaccination. Conclusion: Knowledge about cervical cancer in women is still low. Women only have a general idea of cervical cancer. However, women show a good attitude about cervical cancer screening, because cervical cancer can cause death and if early diagnosis of the disease is very helpful in preventing disease.