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Viral evolution is a subdiscipline of evolutionary biology and virology that focuses on the evolution of viruses. Many viruses, especially RNA viruses, have relatively high mutation rates and short production durations (on the order of one point mutation or more per genome per round of replication). The rapid pace of viral mutation paired with natural selection enables viruses to rapidly adapt to changes in the host environment, despite the fact that the majority of viral mutations offer little benefit and frequently prove to be harmful. Additionally, because viruses often make several copies in an infected host, altered genes can be rapidly transmitted to a large number of offspring. The high mutation rates of RNA viruses, which are the result of an error-prone RNA-dependent RNA polymerase, make them a veritable gold mine for researchers interested in discovering evolutionary novelty and developing new methods to study evolution in action. There are two different forms of genetic changes: antigenic drift and antigenic shift. This article covers briefly the evolution of viruses in terms of genetic variation.  

21st century learning has had a huge impact on students and teachers. Students must be guided to be able to think critically to overcome various kinds of problems that occur. Furthermore, teachers as education play an important role in honing problem solving skills in their students. The problem solving learning model is a learning model that directs students to solve problems in the learning process. In addition, the problem solving learning model is not fully capable of being applied by science teachers. Although, in the 2013 curriculum in Indonesia a teacher is required to be able to apply the problem solving model in conducting science learning. Not only that, the limited experience of teachers in applying variations of these learning models is still the main obstacle in learning science. So, teachers in Indonesia must have extensive experience in adopting problem solving learning models. This study aims to determine the effectiveness of the problem solving learning model in learning science in Indonesia. This research is a kind of meta-analysis research. The research sample came from analyzing national and international journals published from 2010-2022. The selection of data used as samples was carried out very strictly and thoroughly. Searching for this research sample through Google Scholar, Eric, Hindawi, Sage, Springer, Proquest, IEEE, DOAJ, and Wiley. The sample selection technique is a purposive sampling technique. In this technique, the data that is used as a sample must have a relationship with the research variable. In searching for sample keywords, namely problem solving learning models in learning science (Biology, Chemistry and Physics) in various schools in Indonesia. Data analysis is descriptive statistical analysis with the OpenMEE application. Data analysis was performed by calculating effect size, standard deviation (SD), average value (mean), and N-gain. The results of this study concluded that the application of the problem solving learning model was very effective in learning science in Indonesia. This learning model is able to increase student learning outcomes with an average score of 86 students in the experimental class and 65.5 in the control class, the effect size value is 1.39 in the high category and N-Gain is 0.55.

Carangwulung village located in Wonosalam sub-district, Jombang district has the potential of abundant natural resources from plantation products ranging from bananas, durian, salak, to coffee. The large number of products produced in the Segunung Traditional Village is an interesting addition for implementers to focus on increasing promotions and marketing activities that can be carried out independently by the Segunung Traditional Village. The facilities owned by the Segunung Traditional Village ranging from coffee plantations, coffee shops, and springs should be able to make economic potential and tourism education potential that can be offered and make Segunung Traditional Village into a village that has independence in terms of the creative economy. However, the potential possessed by this Traditional Village is still not a tourism product that is well packaged and attractive for tourists who visit in a sustainable manner. This is partly due to the fact that activities have not been documented, village products are not properly published and are not published in an interesting way. Dusun Segunung has several social media options, but partners feel that creative content ideas are very difficult to grow. Starting from how photos, videos of creative products and designs can be managed properly and produced sustainably. The method of implementing community service is in the form of consultation, socialization and assistance on digital marketing strategies, especially in the form of creative videos and social media management. The socialization and mentoring covered material and practice on videography and video editing techniques using simple technology, smartphones. Through this activity, partners are expected to be able to optimize social media in promoting the potential of their villages, events and business products in order to reach a wider market so that business development and progress can ultimately increase the income of the Segunung Traditional Village.

Along with the time that continues to turn where previously children who were still toddlers were taken care of by their parents until they moved to the village and got a job and were busy to have a partner and offspring and their own lives, on the other hand the parents who used to raise them have now entered old age which should be the child's obligation to take care of parents at that time. The dilemma that occurs between the obligation to care for wives and children and work with caring for parents when they enter old age or old age. Responding to the phenomenon that occurs related to the child's obligation to choose parents when entering old age. So the service team from the Faculty of Law, Goronalo State University conducted counseling in a number of villages which basically had a number of problems related to this, including Kaaruyaan Village, Paguyaman District, Boalemo Regency, Gorontalo Province. The problems raised in this service include the background of children taking care of their own elderly parents at home and children who entrust elderly parents in nursing homes. Legal review of the responsibilities of children who entrust their parents in nursing homes. This research method uses qualitative methods and discussions in counseling, where the research was carried out in the Kaaruyaan Village area. The subjects of counseling are children who care for and children who entrust elderly parents (Elderly) in Nursing Homes. Observation, interviews and documentation. Extension results. The background of children choosing to entrust elderly parents in the orphanage is triggered by a number of things including work, obstacles in communication between family and parents, incompatibility between the wife / husband and parents in the house. While the background of children chooses to take care of their own parents at home, facilitate communication with parents, control physical health, guarantee the needs and needs of parents daily to apply forms of love and affection to parents.

This study aims to obtain an effective solar panel tracking mechanism using energy-efficient electric actuators. Furthermore, we designed and implemented a semi-active solar tracking system. A tracking system is proposed to control solar panel orientation using a moving mass, a spring system, and an actuator. The weight of the moving mass and the spring constant are optimized to reduce actuator size. A stepper motor was used for this case. This electric drive is not the prime mover of the solar tracker; hence, it works against mass elements lighter than solar panel weight as used in the active solar tracker. Experimental results suggest that the average power required by the stepper motor is 0.21% of the energy generated by the solar tracking system. The results indicate that the proposed solar panel tracker works satisfactorily to control solar panel orientation.

Promas Greenland Nglimut Is a Hot Spring Bath and Villa Accommodation, Promas Greenland Ngonut Gonoharjo is located at an altitude of 700m above sea level, located in Limbangan District and 30 km from the city of Semarang. The purpose of this study is to introduce to the public so that people are more aware of greenland promas tourism, as well as interested in traveling to greenland promos gonoharjo and increasing marketing of greenland promasan tourism to be able to compete with other tourism in Kendal district. This study uses the Aida method and uses a 3D model. The subject of this research is to the public and tourists who will visit Greenland promasan tourism. The results of this study were able to attract the public or tourists to visit Greenland promising tourist sites and improve their marketing system, the results obtained from marketing with 3D models are able to improve the marketing system that the public will find out the specifications and forms of Greenland promotions before visiting or traveling. This is supported by the existence of good management and adequate facilities so that visitors feel comfortable and happy.