Publication Search

Inflammation is the body's response when it experiences injury, infection, antigen or cell damage, so it is a sign of something that is harmful to the body or disease. Galangal rhizomes (Kaempferia galanga L.) and Srikaya leaves (Annona squamosa L.) are plants that contain flavonoid compounds which have anti-inflammatory potential by inhibiting the enzymes cyclooxygenase and lipooxygenase. The aim of this research was to determine the effectiveness of a combination cream preparation of galangal rhizome extract and srikaya leaf extract as an anti-inflammatory. The various combinations used are a combination of 15 grams of kecur rhizome extract and 10 grams of srikaya leaf extract, 12.5 grams of srikaya rhizome extract and 12.5 grams of srikaya leaf extract, 10 grams of srikaya rhizome extract and 15 grams of srikaya leaf extract. The anti-inflammatory test uses 1% carrageenin induction of 0.1 ml, then the swelling that occurs is measured using a plastinometer. Based on the results obtained, a good anti-inflammatory power value was a combination of 15 grams of kencur rhizome extract with 10 grams of srikaya leaf extract with a value of 21.6216%. The results of the One Way Annova analysis obtained a p-value >0.05, which means there is no significant difference. So it can be concluded that various combinations of galangal rhizome extract and srikaya leaves are effective in mice induced by carrageenin. A post hoc Tuckey test was carried out on the AUC value, obtaining a p-value >0.05, so it can be concluded that there was no significant difference in the positive controls for formulas 1, 2 and 3.

Diarrhea is a condition in which a person defecates with a soft or runny consistency, it can even be water alone and the frequency is more frequent (usually three or more times) in one day. One of the beneficial plants is the Moringa oleifera Lam. Plant. Flavonoids, tannins and steroids in Moringa leaves are thought to be anti-diarrhea. This study aims to determine the antidiarrheal activity of the ethanol extract of Moringa oleifera Lam. Leaves against male white mice (Mus musculus) induced by Oleum ricini. Observations were made for 3 hours. This research is an experimental study divided into 6 groups, namely the normal group, positive control (Loperamid HCl), negative control (Na CMC), and ethanol extract of moringa leaves at a dose of 200 mg / KgBB, 400 Mg / KgBB and 800 mg / KgBB. Numeric data were processed using SPSS with One Way ANOVA test. The results showed that the optimal dose was 200 mg / KgBW in the ethanol extract of Moringa oleifera Lam. Leaves as an antidiarrheal in male white mice (Mus musculus) induced by Oleum ricini.

Insomnia is a sleep disorder that often occurs in teenagers. Insomnia can be treated using sedative hypnotic drugs but this can cause dangerous effects. Therefore, alternative natural ingredients are needed, such as Putri Malu and Secang, which are formulated in the form of jelly drinks as nutrasetikals. This research used 20 female mice as test animals which were divided randomly into 5 grups. The method used was the Traction Test and the data collected was the length of time the mice turned and the time the mice fell. In the positive control grup, Diazepam, distilled water and agar, the average time for mice to fall was 62.5 seconds and the time to turn around was 62.9 seconds. In the negative control grup, Jelly Drink combination of Putri Malu and Secang 0.68 g/kgBW, showed that the time for mice to fall was 106.6 seconds and the time to turn around was 128.5 seconds. In conclusion, the Jelly drink combination of Putri Malu and Secang has a sedative effect and has the potential to prevent insomnia as seen by the need for mice in the Jelly drink grup who had less time to fall and turn around.

This research delves into the development of the tourism sector in Makassar through the lens of the concept and the role of the United Nations World Tourism Organization (UNWTO) in the Meetings, Incentives, Conventions, and Exhibitions (MICE) in Makassar. Employing a qualitative method and document analysis, the study explores the implementation of sustainable tourism principles amidst technological evolution. UNWTO is identified as a key catalyst in driving the adoption of cutting-edge technology in the tourism sector, enhancing tourism security, and improving industry skills. The research findings indicate that collaboration with UNWTO can have a positive impact on advancing tourism in Makassar, particularly in introducing innovative technologies and enhancing service quality. This study provides a profound understanding for stakeholders regarding sustainable tourism development strategies, positioning Makassar as a prominent destination. The implications of these research findings stimulate further considerations, including strengthening collaboration with UNWTO, continuously improving tourism infrastructure, and intensifying industry training to ensure the sustainability and competitiveness of this destination on the global stage.

Medicinal plants have been known and used worldwide for thousands of years. One type of medicinal plant that is often used is gaharu. The efficacy of gaharu leaves provides properties as a fever reducer, increases appetite, launches menstruation, and relieves pain. This study aims to determine whether there is an analgesic effect from the methanol extract of gaharu leaves in male Wistar rats using the heat stimulation method. This study was an experimental study using twenty-five male Wistar rats divided into five groups. Group I (negative control), rats were treated with 1% CMC-Na. Group II (positive control), rats treated with mefenamic acid 45 mg/kg BW. Group III, IV, and V rats were treated with gaharu leaf methanol extract suspension (100; 200, and 400) mg/kg BW. Pain stimulation was carried out by dipping the rat tail into a 40°C water bath. Data on response time to pain, stimuli were analyzed using the One-Way Analysis of Variance (ANNOVA) method with a 95% confidence level followed by a post-hoc Tukey test to determine which group had the same or significantly different effect. The results showed that the normal response time data for mice to painful stimuli ranged from 2.79 to 3.57 seconds. 1% CMC-Na treatment in mice was unable to increase the response time to a significant pain stimulus (p>0.05). Mefenamic acid treatment 45 mg/Kg BW significantly increased the response time to painful stimuli (p<0.05) with the longest average response time to painful stimuli, namely 8.87 seconds. Based on the method used in this research, methanol extract of agarwood leaves 400 mg/kgBW has almost the same analgesic effect as mefenamic acid 45 mg/KgBW.

Medicinal plants have been known and used worldwide for thousands of years. One type of medicinal plant that is often used is gaharu. The efficacy of gaharu leaves provides properties as a fever reducer, increases appetite, launches menstruation, and relieves pain. This study aims to determine whether there is an analgesic effect from the methanol extract of gaharu leaves in male Wistar rats using the heat stimulation method. This study was an experimental study using twenty-five male Wistar rats divided into five groups. Group I (negative control), rats were treated with 1% CMC-Na. Group II (positive control), rats treated with mefenamic acid 45 mg/kg BW. Group III, IV, and V rats were treated with gaharu leaf methanol extract suspension (100; 200, and 400) mg/kg BW. Pain stimulation was carried out by dipping the rat tail into a 40°C water bath. Data on response time to pain, stimuli were analyzed using the One-Way Analysis of Variance (ANNOVA) method with a 95% confidence level followed by a post-hoc Tukey test to determine which group had the same or significantly different effect. The results showed that the normal response time data for mice to painful stimuli ranged from 2.79 to 3.57 seconds. 1% CMC-Na treatment in mice was unable to increase the response time to a significant pain stimulus (p>0.05). Mefenamic acid treatment 45 mg/Kg BW significantly increased the response time to painful stimuli (p<0.05) with the longest average response time to painful stimuli, namely 8.87 seconds. Based on the method used in this research, methanol extract of agarwood leaves 400 mg/kgBW has almost the same analgesic effect as mefenamic acid 45 mg/KgBW.

Oxidative stress is a condition where there is an imbalance between oxidants and antioxidants in the body which can trigger psychological stress. Oxidative stress can be reduced by consuming exogenous antioxidants (antioxidants from outside), where green tea is thought to be able to reduce oxidative stress. The aim of this study was to examine the effect of steeping green tea on blood glucose and Malondialdehyde (MDA) levels in male Wistar Strain white rats exposed to psychological stress. The design used in this research was Randomized Post Test Only Group Design. There were 5 groups of mice; 2 are a normal control group and a stress control group, and 3 treatment groups. Previously, the mice were given psychological stress 1 x 24 hours in the form of disturbed sleep patterns, so that the experimental animals experienced oxidative stress, then green tea was given to the treatment group with a single dose of 3.6 ml/head in the 1st hour in the group. treatment 1, 6th hour in treatment group 2, and 24th hour in treatment group 3. Statistical analysis used the Manova test.  Based on statistical analysis, it shows that there was a decrease in blood glucose and Malondialdehyde (MDA) levels in all treatment groups given exposure to psychological stress and steeping green tea.  A single dose of green tea brewing in experimental animals experiencing oxidative stress was proven to be able to neutralize oxidative stress in the 1st hour after administration of green tea brewing and the antioxidant activity still lasted up to 24 hours.

Over time, it is not only the tourism industry that has the potential to support the MICE industry, one of which is educational institutions such as vocational schools and equivalent. However, there are three factors that need to be considered, namely Hall management, supporting facilities, and work programs, so that good MICE services are obtained and are able to gain profits for the institution. Trisakti Ngawi Vocational School (SMK Trisakti Ngawi) has professional Hall management, adequate Hall support facilities and a suitable work program to carry out MICE (Meeting, Incentive, Conference and Exhibition) activities

This research aims to determine the satisfaction of MICE participants at the UNP Hotel & Convention Center. This research focuses on MICE activities in the form meeting and conference. This research is entitled The Influence of Services and Facilities on the Satisfaction of Participants in MICE at the UNP Hotel & Convention Center. The data collection technique for this research is indirect communication by distributing questionnaires with a Likert scale to meeting and conference participants then the data processed using the SPSS program. This research is a quantitative descriptive with a causal associative approach. The population of this study were people who had participated in meeting and conference activities at the UNP Hotel & ConventionCenter in the period July-December 2022 with a sample of 98 people, and the sampling technique was non-probability sampling with a minimum age of 18 years. There are 2 types of data used in this research, namely primary data and secondary data. The results of this research show that service is in the very good category (80,61%), facilities are in the very good category (74,50%), and participant satisfaction is in the very satisfied category (87,75%). It was found that the R square value was 0.464 with an F count of 41,072 and a significance level of 0.000<0.05 and the t value was 11,529 with a significance level of 0.000<0.05 meaning that variable X influenced variable Y significantly by 46.4%. It was found that the regression coefficient value of the service variable was 0.346 with a significance of 0.000<0.05, which means that every increase of 1 unit of service will increase participant satisfaction by 0.346 units of satisfaction, and the coefficient value of the facility variable was 0.530 with a significance of 0.000<0.05, which means every increase of 1 facility units will increase participant satisfaction by 0.530 satisfaction units.

Men's participation in the Family Planning (KB) program is still very minimal due to the limited choice of contraceptive methods. Efforts need to be made to develop contraceptive methods, one of which is using natural ingredients. Bitter melon (Momordica charantia L) is known to have potential benefits as a male antifertility agent. This research used an experimental design with a sample size of 20 mice divided into 4 groups randomly. Treatment groups 1-3 were given different doses, namely 100, 80, 60 mg of bitter melon ethanol extract/100g BW/day, and the control group was given distilled water for 35 days. The mice were sacrificed the day after the last dose, then spermatozoa were collected from the epididymis and their number, motility, viability and morphology were examined. The results of this study showed a significant decrease in the number and motility of spermatozoa and was directly proportional to the size of the dose given. In terms of viability parameters, there was a significant decrease at all doses. Meanwhile, for spermatozoa morphology, only a dose of 100 mg had a significant impact. The conclusion from the results of this research is that giving bitter melon fruit extract has an effect on the number, motility, viability and morphology of spermatozoa. The most effective dose is 100 mg/100 gBB/day.

Diuretics act on the kidneys to increase the excretion of water and sodium chloride. The working principle of diuretics in general is to reduce electrolyte reabsorption by the renal tubules, where an increase in electrolyte excretion will be accompanied by an increase in water excretion which is needed to achieve osmotic balance. Bangun-Bangun leaf contains polyphenolic compounds, saponins, glycosides, flavonoids, and essential oils. Bangun-Bangun leaves types of flavonoids, namely quercetin, apigenin, luteolin, salvigenin, and genkwanin. Apigenin is known as a compound that functions as a diuretic. IDBB was obtained from the infusion technique with distilled water and then the infusion was used on 25 diuretic rats which were divided into 5 groups. Group I (negative) Na-CMC 0.5%, group II, III, IV, IDBB doses of 10, 20, 40%, and group V (positive) Furosemide 3.6 mg/kgBW were given orally. Rats were given aquadest orally at a dose of 15 ml/kgBW. Mice were placed in metabolic cages, then a physical examination of urine was carried out every 1 hour for 6 hours. The results showed that the IDK with the best dose was 40% which gave an increase in urine volume, had an effect on urine pH, had an effect on urine specific gravity, had an effect on urine color, and had an effect on urine clarity.    

In previous research, mango rind extract has been studied as an antioxidant, antihypertensive, and antidiabetic, because it contains flavonoids and 17% mangiferin compounds. In this research, the effect of arumanis mango rind extract gel (Mangifera indica L.) as an anti-inflammatory was tested in male white mice induced by carrageenan using the granuloma pouch method. This experimental study used experimental white male mice which were grouped into 5 groups: the control group, the group with 2% mango rinf extract, the group with 4% mango rind extract, the group with 8% mango rind extract, and the comparison group. The parameters that were analyzed were exudate volume, total leukocytes, and type of leukocytes on days 3, 5, 7. The results showed that mango arumanis (Mangifera indica L.) rind extract had anti-inflammatory effectiveness topically as indicated by a decrease in the average exudate volume, total leukocytes, and leukocyte cell types (segmented neutrophil cells and lymphocyte cells) in each concentration group of mango rind extract, based on two-way ANOVA test and Duncan's test showed significant differences with respect to concentration and time (p<0.05). It can be concluded that all gel concentrations of arumanis mango rind extract (Mangifera indica L.) 2%, 4%, and 8% have anti-inflammatory effects.

  This article analyzes the interpretations and metaphors on the lyric of Iwan Fals song. This research was also conducted using the hermeneutic  approach which showed that is  was descriptive. There are also metaphors used in the "Tikus-tikus Kantor" song such as mice, cats and shrimp. One of the interesting thing is that the lyrics of this song are not expressed clearly but uses figure of speech. Research has shown that the song is about public criticism of corruption by government officials and law enforcement agencies.    

Penelitian ini bertujuan untuk mengevaluasi potensi Meetings, Incentives, Conferences and Exhibitions (MICE) sebagai tulang punggung pariwisata di Bali. Bali adalah salah satu destinasi wisata paling populer di dunia, menyumbang 43% dari total kunjungan wisatawan asing ke Indonesia pada tahun 2016. MICE merupakan sektor penting bagi pariwisata karena dapat meningkatkan pendapatan dan membuka lapangan kerja. Metode penelitian yang digunakan dalam studi ini adalah kualitatif, menggunakan data dari tinjauan pustaka dan wawancara dengan stakeholder industri. Hasil penelitian menunjukkan bahwa Bali memiliki potensi untuk menjadi destinasi MICE utama di Indonesia. Untuk meningkatkan potensi MICE di Bali, pemerintah dan stakeholder industri perlu bekerja sama untuk mengatasi hambatan tersebut dan mengembangkan strategi untuk mempromosikan Bali sebagai destinasi MICE.

Tujuan dilakukannya penelitian ini adalah untuk mengetahui  bagaimana  mekanisme penyelesaian pelanggaran pemilukada serentak oleh lembaga peradilan dan bagaimana penyelesaian perkara pemilukada serentak melalui lembaga peradilan sehingga diperlukannya peradilan khusus pemilu dalam pemilukada serentak.   Dengan menggunakan metode penelitian yuridis normatif, maka dapat disimpulkan: 1. Peradilan khusus dalam untuk pemilihan kepala daerah yang berkeadilan, sengketa pilkada sering menumpuk karena diselesaikan melalui Mahkamah Konstitusibdan permasalahan yang diselesaikan Peradilan Umum khusus pilkada yang diatur didalam Undang-Undang Nomor 32 Tahun 2014. 2. Persoalan penegakan hukum dalam pemilu mencakup tiga ranah hukum yaitu: Sengketa hasil yang diselesaikan di Mahkamah Konstitusi, Penyelesaian perkara pidana pemilu deselesaikan melalui Pengadilan Negeri, Penyelesaian  pelanggaran  administrasi dilakukan oleh Komisi Pemilihan Umum, Komisi Pemilihan Umum Provinsi, Kabupaten/Kota berdasarkan laporan Bawaslu dan panwaslu. Pembentukan peradilan khusus pemilu sebenarnya suatu solusi untuk mewujudkan salah satu komponen terpenting dalam azas- azas penyelenggaraan pemilu diantaranya adalah kepastian hukum.

Hyperglycemia occurs when the body's condition is too much blood glucose that exceeds normal limits in the body because the body does not produce insulin properly. Betel leaves and ginger rhizomes have long been used by the people in Indonesia as traditional medicines that are believed to reduce blood glucose levels. This study aims to determine the effectiveness of betel leaves and ginger rhizomes empirically to reduce blood glucose levels in hyperglycemia male rats. Betel leaves and rhizomes of ginger are made in the form of infusions and used on 30 heads of hyperglycemia mice divided into 6 groups. Normal group, negative group induced alloxane, positive group (glibenklamide), betel leaf infusion group, ginger rhizome infusion group, betel leaf infusion combination group and ginger rhizome infusion, testing was carried out for 30 days. Data were analyzed with IBM SPSS 20.0 ANOVA and post hoc tukey HSD assays. The results showed that betel leaf infusion at a dose of 2 ml / kg BB and ginger rhizome infusion dose of 2ml / kg BB single administration could reduce blood glucose levels while in combination administration it was seen that there was less effective in reducing blood glucose levels in male white rats.    

       Penelitian ini bertujuan untuk menganalisis pengaruh variable Kualitas layanan dan Fasilitas terhadap Loyalitas pelanggan di Patra Semarang Hotel & Convention. Jumlah responden adalah sebanyak 90 responden. Pengukuran dalam kuesioner menggunakan skala likert. Metode analisis data menggunakan Output Program SPSS Statistics versi 16.0 for windows. Hasil pengujian terhadap hipotesis, menunjukkan bahwa variable Kualitas layanan berpengaruh positif dan significan terhadap Loyalitas pelanggan dengan dimensi Kehandalan ( Reliability ) yang paling dominan terhadap Loyalitas pelanggan dengan hasil penghitungan rata – rata variable responden di perolehhasil 4,30, dari indicator Patra Semarang Hotel & Convention handal dalam memberikan pelayanan dengan segera dan memuaskan. Pengaruh Kualitas layanan terhadap Loyalitas pelanggan di Patra Semarang Hotel & Convention perlu di tingkat kandan di maksimalkan, sikap ramah tamah karyawan dan memberikan rasa aman kepada pelanggan serta meningkatkan semua aspek fasilitas baik bentuk fisik maupun non fisik yang nantinya akan berpengaruh pada semakin banyaknya pelanggan sehingga juga akan berimbas pada kesejahteraan karyawan.

Scientific study activities on tourism, mice, and marketing communications. The activities carried out are in the form of participating in discussions and assigned to attend seminars, aiming to enrich knowledge about tourism, mice and marketing communications. This activity is a practice to process vendor data that will collaborate with the office into one in the service provider partner file. Both transportation, accommodation, restaurants, logistics and human resources. Aims to collect data on cooperation partners so that the data is neat and can be searched at any time when needed

Pain is a defense mechanism of the body and caused by tissue damage to the body due to injury, accident or medical action. Traditionally, cashew leaves were used in curing inflammation, pain, toothache, wound healing, rheumatism as well as dysentery. This study aims to determine the effectiveness of analgetic power of cashew leaf ethanol extract (Anacardium occidentale L.) in white rats (Rattus norvegicus). The research conducted is experimental research, with chemical excitatory methods. The test animals were divided into 5 groups with each treatment of 3 mice. Group I Na CMC 1%, group II Paracetamol, group III cashew leaf ethanol extract 10%, group IV cashew leaf ethanol extract 20%, and group V cashew leaf ethanol extract 40% given orally. Pain inductors are 1% induced acetic acid intraperitonially. Observed the amount of mice geliat for 1 hour and calculated percent analgetic power. The results obtained in this study have properties as analgetics with analgetic power concentration of 10%: 82.73%, concentration of 20%: 84.89%, and concentration of 40%: 88.48%.