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Sorghum (Sorghum bicolor L.) is an annual crop that is tolerant to drought and requires relatively low water input, making it suitable for cultivation on suboptimal lands such as peat soils. However, the utilization of peat soils for crop production faces major constraints, including high soil acidity and low availability of essential macronutrients, particularly nitrogen (N), phosphorus (P), and potassium (K). Improving the chemical properties of peat soils can be achieved through the application of dolomite to reduce soil acidity and NPK fertilizer to enhance nutrient availability. This study aimed to evaluate the growth and yield responses of sorghum to different combinations of dolomite and NPK fertilizer rates on peat soil and to determine the most efficient dosage. The experiment was conducted using a factorial randomized block design with two factors, namely dolomite rate and NPK fertilizer rate. Observations were made on growth and yield parameters of sorghum. The results showed that the interaction between dolomite and NPK fertilizer had no significant effect on all observed parameters. Based on efficiency analysis, the application of 1.16 kg dolomite per bed and 200 kg NPK per hectare was identified as the most efficient dosage to support the growth and yield of sorghum on peat soil. These findings indicate that appropriate soil amendment and fertilization management are essential for optimizing sorghum production on peat soils.

As a high-value crop, potatoes necessitate balanced nutrient management for optimal growth and yield. This research aimed to assess how varying applications of NPK 20-20-10 fertilizer influenced potato growth, yield, tuber quality, agronomic efficiency, and economic viability within tropical climates. The experimental setup involved a randomized complete block design, incorporating four replications across seven distinct treatments: a control, a standard inorganic fertilization regimen, and NPK 20-20-10 applied at 0.50, 0.75, 1.00, 1.25, and 1.50 times the suggested dosage. The findings indicated that applying NPK 20-20-10 significantly enhanced several parameters, including plant height, branch count, tuber count, tuber weight, and overall yield components, when contrasted with the control group. Notably, the 1.25 times recommended dose demonstrated superior performance, leading to a 34.9% increase in tuber number and a 68.6% rise in tuber weight compared to the control. Agronomic effectiveness scores surpassed 100 for dosages ranging from 0.75 to 1.50, with the 1.25 dose registering the peak value. Economic evaluations confirmed the profitability of all NPK treatments, and the 1.25 dose yielded the most favorable R/C ratio and a net profit of IDR 29,053,400. Consequently, the recommended application for potato cultivation is 675 kg/ha of NPK 20-20-10, distributed in three equal parts at planting, four weeks post-planting, and six weeks post-planting. Thus, these results underscore that NPK 20-20-10, when applied at 1.25 times the recommended rate, presents an agronomically effective and economically sound strategy for sustainable potato farming in tropical settings.

Sweet corn is a horticultural commodity that is widely consumed in Indonesia. This study evaluated the effectiveness of NPK 18-18-18 fertilizer on the vegetative growth, yield components, and relative agronomic effectiveness (RAE) of sweet corn (Zea mays saccharata). Field experiments were conducted using fertilizer dosages of 0,50, 0,75, 1,00, and 1,50 NPK, with a control treatment for comparison. The application of NPK 18-18-18 significantly increased plant height, stem diameter, leaf number, ear length, ear diameter, biomass weight, ear weight with husk, ear weight without husk, plot yield, and overall productivity compared with the control. Mean values across treatments ranged from 68,94–205,72 cm for plant height, 7,41–20,47 mm for stem diameter, 6,01–13,00 leaves per plant, 15,41–20,89 cm for ear length, and 36,05–49,65 mm for ear diameter. Biomass weight ranged from 0,12–0,34 kg, ear weight with husk from 0,13–0,34 kg, and ear weight without husk from 0,12–0,28 kg. Plot yield varied between 7,91–25,46 kg, corresponding to productivity levels of 5,02–16,16 t/ha. RAE analysis indicated that fertilizer application was effective at dosages of 0,75, 1,00, and 1,50 NPK, with the highest effectiveness observed at 1,50 NPK (118%). Notably, the 0,75 NPK dosage achieved an RAE value of 101%, demonstrating that lower fertilizer input can enhance yield while reducing production costs and mitigating fertilizer scarcity. These findings suggest that NPK 18-18-18 fertilizer, when applied at an optimal dosage, can be effectively utilized in sweet corn cultivation to improve growth and productivity while ensuring efficient nutrient management.

This study aims to describe the implementation and outcomes of training on making herbal elixir beverages from nine spice butterfly pea ingredients for exercise mothers as an effort to improve knowledge and skills in processing healthy drinks. The activity was motivated by the limited use of herbal beverages after exercise and the low level of public understanding regarding the benefits of butterfly pea flowers and traditional spices as natural stamina enhancers. The study applied a descriptive qualitative approach through observation and documentation conducted from November 22 to December 5, 2025. A total of 25 exercise mothers participated in the training, which consisted of demonstrations and direct practice in preparing elixirs using dried butterfly pea flowers combined with ginger, turmeric, galangal, lemongrass, cinnamon, cloves, betel leaves, and brown sugar. The results show that participants were able to follow all training stages properly and demonstrated increased understanding of herbal benefits, ingredient functions, dosage accuracy, and processing procedures. Achievement indicators reveal that 92 percent of participants were able to independently prepare the elixir according to the demonstrated steps, 84 percent were able to explain the function of each ingredient correctly, and all groups successfully produced elixir products with color, aroma, and taste that met the expected standards. Participants also responded positively and expressed interest in reapplying the recipes at home and developing flavor variations for personal consumption or small scale business opportunities effectively.

The puring plant (Codiaeum variegatum), which has been known as an ornamental plant, apparently has significant therapeutic potential, supported by the presence of secondary metabolites such as flavonoids, tannins, saponins and alkaloids. Various modern studies report the biological activity of croton leaves, including anti-cholesterol, anti-hyperglycemia, antibacterial effects, and their use in biosurfactant formulations. However, studies on how varying extract concentrations influence bioactivity parameters quantitatively are still limited, especially in the context of dose-response relationships involving many biological parameters in one series of research. Therefore, this research was conducted to evaluate eight bioactivity parameters, namely PSM, SSSP, DSSP, SL, RO, SM, PSL, and ANA at croton leaf extract concentrations of 1%, 2%, and 4%. This research uses a laboratory experimental approach by extracting croton leaves through a maceration method using ethanol, then formulated in three concentration levels. Each parameter was analyzed quantitatively to observe the pattern of changes in biological response to variations in the dose administered. The results showed that most of the PSM, SSSP, DSSP, SL, and PSL parameters showed an optimum response at a concentration of 2%, which indicates that there is a most effective dose point before a decrease in activity occurs at the highest concentration. In contrast, several parameters such as RO, SM, and ANA showed a more fluctuating response, even the ANA parameter gave the highest value at a concentration of 4%, indicating that certain activities require higher compound levels to be achieved. In general, the response pattern found was not linear, but instead formed an optimum curve typical of the bioactivity of plant extracts. These findings confirm that determining dosage is very important in the use of croton leaf extract, both for pharmacological purposes and for the formulation of natural ingredient-based products.

Corticosteroids are hormones that play an important role in the human physiological system, affecting self-defense against environmental changes. However, the perception of their efficacy often drives irrational self-medication behavior in the community, which can lead to detrimental effects if used long-term without supervision. This community service activity was carried out in Kepolorejo Village, Magetan Regency, based on initial observations showing errors in corticosteroid use, such as doubling dosages. The method used was educational counseling with material presentation and Q&A discussions regarding irrational corticosteroid use. Knowledge measurement was conducted through pre-test and post-test questionnaires. The results showed an increase in public knowledge regarding the impact of irrational steroid use.

This community service activity aims to increase the ability and creativity of the people of Situnggaling Village, Brand District, Karo Regency, in utilizing the potential of the surrounding nature in the form of telang flowers (Clitoria ternatea L.) through training in making simple syrup products. This training was attended by 34 participants consisting of housewives and village teenagers. The implementation method includes socialization of the benefits of telang flowers, syrup making demonstrations, as well as technical assistance in packaging and marketing strategies. Participants were also given an understanding of hygiene standards, the right dosage of ingredients, natural dyeing techniques, and product storage procedures to have a longer shelf life. In addition to the production aspect, this activity also discussed the economic potential of telang flower syrup products as a commodity for MSMEs, including the calculation of production costs and marketing opportunities through social media. The results showed a significant increase in participants' knowledge about the economic value and health benefits of telang flowers, as well as their ability to produce syrup independently. This activity is expected to be the first step in empowering the local potential-based economy and encouraging the formation of new sustainable home businesses in Situnggaling Village.

Mimosine is an aromatic amino acid found in Mimosa pudica L. (sensitive plant) and is known to possess toxic properties that can damage various organs, including the kidneys. This study aimed to investigate the effect of ethanolic root extract of Mimosa pudica on renal damage in mice (Mus musculus). Twelve mice were divided into four groups: a control group and three treatment groups that received ethanolic root extract of M. pudica at doses of 10 mg/mouse/14 days, 100 mg/mouse/14 days, and 1000 mg/mouse/14 days. Following treatment, the mice were dissected to measure serum creatinine levels as an indicator of renal function, and histopathological observations of kidney tissues were performed using Hematoxylin-Eosin staining. The results revealed that administration of the ethanolic root extract of M. pudica significantly increased serum creatinine levels (P < 0.05), indicating impaired renal filtration function. Histologically, several types of tissue damage were observed, including glomerular atrophy, hydropic degeneration, and cellular necrosis, with hydropic degeneration being the most predominant and glomerular atrophy the least frequent. These findings suggest that mimosine, an active compound in M. pudica roots, exhibits a dose-dependent nephrotoxic effect, where increasing extract concentrations exacerbate renal tissue damage. Therefore, caution is advised in the medicinal use of M. pudica, as despite its pharmacological potential, high-dose or prolonged exposure may pose a serious risk of renal dysfunction.         

The understanding of the doctrine of humanity and sin in Christian theology reveals the essence of human nature and the need for divine redemption. This study aims to examine theological perspectives on human nature and sin, focusing on the relationship between the Imago Dei and the fall of humanity. Using a qualitative descriptive approach through literature review, the research analyzes biblical texts and theological interpretations from various Christian scholars. The results show that humans, created in the image and likeness of God, were originally good and endowed with moral and spiritual capacity. However, through sin, humans experienced separation from God and moral corruption. Nevertheless, God’s grace through Jesus Christ enables the restoration of humanity’s divine image and reconciles the broken relationship with the Creator. The study highlights that understanding these doctrines helps believers realize their dependence on God’s grace, leading to repentance, transformation, and ethical living. The implication encourages Christians to maintain a responsible, spiritual, and moral life as a reflection of the renewed image of God within them.

Arbuscular Mycorrhizal Fungi (AMF) are biological agents that play an important role in increasing the efficiency of nutrient uptake and plant tolerance to abiotic stress, especially in acidic soils such as ultisols. This study aims to analyze the growth and yield responses of chili (Capsicum annuum L.) to the combination of NPK fertilizer doses and AMF inoculation. The study was conducted in Sungai Talang, Gadut, Agam Regency, from June to October 2025 using a Factorial Completely Randomized Design with two factors, namely AMF inoculation (without AMF, Glomus sp., and Rhizophagus sp.) and NPK fertilizer doses (100%, 75%, 50%, and 25% of the recommendation). The results showed a significant interaction between AMF inoculation and NPK doses on plant height, dry weight, flowering time, and fruit yield per plant. Glomus sp. inoculation with a 50% NPK fertilizer dose resulted in the highest growth and yield, equivalent to the 100% NPK treatment without AMF. The integration of AMF with a 50% reduction in NPK dosage has been shown to maintain crop productivity. This strategy can serve as a basis for developing a sustainable agricultural system based on nutrient efficiency and soil microbial balance.

The aim of this research is to determine the effect of using NPK 16:16:16 fertilizer dosage on the growth and yield of white mustard (Brassica Pekinensis) ITTO variety to determine the effect of using organic kasgot biochar fertilizer on the growth and yield of white mustard (Brassica Pekinensis) ITTO variety  of white mustard (Brassica Pekinensis) ITTO variety to determine the interaction between the treatment of 16:16:16 fertilizer dosage and organic kasgot biochar fertilizer on the growth and yield of white mustard (Brassica Pekinensis) ITTO variety.This study was conducted in the land of UPT BIH (Horticulture Parent Seed Task Force Unit) Kutagadung, Berastagi District, Karo Regency, North Sumatra. The study was conducted in November 2023 - December 2023. This study used a factorial randomized block design consisting of two factors, namely: Factor I. Provision of Kasgot Biochar Fertilizer (K) with 4 levels, namely: K0 = Control, K1 = 1 kg / plot, K2 = 2 Kg / plot. Factor II. Application of NPK Fertilizer 16:16:16 (P) with 4 levels, namely N0 = Control N1 = 10 grams/plot, N2 = 20 grams/plot, N3 = 30 grams/plot The results of the study showed that the Use of Kasgot Biochar Fertilizer (K) was significantly different from plant height, plant diameter, leaf width, fresh weight per crop of sample plants, fresh weight of plants per plot and production per hectare. The best treatment was the K2 treatment (2 kg/plot). The use of NPK Fertilizer (N) was significantly different from plant height, plant diameter, leaf width, fresh weight per crop of sample plants, fresh weight of plants per plot and production per hectare. The best treatment of N-P-K 16-16-16 fertilizer was the N3 treatment (30 grams/plot), and the Interaction of the use of Kasgot Biochar Fertilizer (K) and NPK Fertilizer (N) was not significantly different from plant height, plant diameter, leaf width, fresh weight per crop of sample plants, fresh weight of plants per plot and production per hectare.

Tonic is a preparation thats can stqrengsthen the body and improve stamina. Curcuma zedoaria and Curcuma aeruginosa are known to have phytochemical compunds such as flavonoids, alkaloids, saponins, tannin, triterpenoids, curcuminoid and polyphenols that can function as stimulant and tonics. This studiy aimed to investigate tonic effects of ethanolic extracts of Curcuma zedoaria, ethanolic extract of Curcuma aeruginosa, and their combinations on male white mice (Mus musculus). Curcuma zedoaria rhizome and Curcuma aeruginosa rhizome were extracted using the maceration method for 3 days using 70% ethanol solvent which was then thickened in a waterbath. A total of 35 male mice were divided into 7 groups with different treatments, including negative control (aquadest), positive control (caffeine 100 mg/kgBB), ethanolic exctract of Curcuma zedoaria (600 mg/kgBB), ethanolic extract of Curcuma aeruginosa (600 mg/kgBB), and combination ethanolic extract of Curcuma zedoaria and Curcuma aeruginosa at dosage of 150:450 mg/kgBB, 300:300 mg/kgBB, and 450:150 mg/kgBB. Tonic effect were evaluated using natatory exhaustion and rotarod tests. The natatory exhaustion test is carried out by observing how long the mice swim, while the rotarod test is carried out by observing how long the mice stay on the rotarod apparatus. The data analyzed using ANOVA and Tukey’s test. The results of One Way Anova showed a there were significansts differensce in each groups (p<0,05) with combination of Curcuma zedoaria : Curcuma aeruginosa (150:450 mg/kgBB) yielding the best tonic effect. From the result of Tukey’s followsup test, it showed that the highers the dosae of Curcuma aeruginosa rhizome extracts the better the tonics effects giiven. This suggest that Curcuma aeruginosa has a dominant role in enhancing phsycal endurance in male white mice.

This research discusses the effect of coconut dregs compost (Cocos nucifera L.) on the growth and yield of tomato plants (Solanum lycopersicum L.) cultivated using polybag media. This research is motivated by the importance of utilizing organic waste, especially coconut dregs, which has not been utilized optimally. Coconut dregs contain organic materials and nutrients that have the potential to increase soil fertility and improve the structure of the planting medium, so it is expected to support the vegetative and generative growth of tomato plants. The research design used was a Randomized Block Design (RBD) with six treatments and four replications. The treatments given were different doses of coconut dregs compost, namely P0 (control without compost), P1 (100 g/polybag), P2 (200 g/polybag), P3 (300 g/polybag), P4 (400 g/polybag), and P5 (500 g/polybag). The parameters observed included plant height, stem diameter, fresh weight, number of fruits per plant, root length, and estimated yield per hectare. The results showed that the application of coconut pulp compost significantly affected several growth parameters, such as plant height, stem diameter, and fresh weight. However, no significant effect was found on the number of fruits per plant or yield per hectare. The most prominent response was seen in the root length parameter, which showed a significant increase with increasing compost dosage. From the observations, the best treatment was at a dosage of 300 g/polybag (P3), which provided an optimal balance between vegetative growth and potential generative yield.

Sweet corn (Zea mays L. saccharata) is a high-value horticultural crop whose productivity is closely linked to effective nutrient management, particularly the balanced application of macronutrients—nitrogen (N), phosphorus (P), and potassium (K). This study evaluates the agronomic and economic impacts of applying NPK compound fertilizer at varying doses (0.5×, 0.75×, 1.0×, 1.25×, and 1.5× the recommended rate) on sweet corn growth and yield performance. Field experiments demonstrated that NPK application significantly enhanced vegetative growth parameters, including plant height, leaf number, and stem diameter, with improvements ranging from 15.8% to 37.3% over the unfertilized control. Yield components such as ear length, husked ear weight, and dehusked ear weight also showed marked increases, resulting in higher total yields per plot and per hectare. Among the treatments, the 1.25× dose achieved the highest relative agronomic effectiveness (RAE) at 147%, indicating superior nutrient utilization and biomass conversion. However, the 1.0× dose yielded the most favorable economic outcome, generating a net profit of Rp. 10,780,200 and an R/C ratio of 1.47, suggesting optimal cost-efficiency. These findings underscore the dual benefits of NPK compound fertilizer in sweet corn cultivation, highlighting that precise dosage not only maximizes agronomic performance but also enhances economic viability. The study recommends adopting the 1.0× dose for balanced productivity and profitability, while the 1.25× dose may be considered in contexts prioritizing yield maximization.

  Medication adherence among pulmonary TB patients is crucial to prevent recurrence and ensurecomplete recovery. Patient knowledge of tuberculosis treatment and adherence to prescribed dosages andadministration methods are key components to successful treatment. This study aimed to determine therelationship between knowledge and medication adherence in pulmonary TB patients at Harapan Anda IslamicHospital, Tegal City. This study used a quantitative cross-sectional design. A sample size of 60 pulmonary TBpatients at Harapan Anda Islamic Hospital, Tegal City, was selected through purposive sampling. Data werecollected using a knowledge questionnaire and a medication adherence questionnaire. Data were analyzed usingthe chi-square test. Based on the analysis results, it was found that of the 60 patients with pulmonary TB atHarapan Anda Islamic Hospital, Tegal City, most were in the early elderly age (46-55 years), most were malebecause they were men, the majority were married, most had graduated from high school and most had privateemployment status. The level of compliance with taking medication in patients with pulmonary TB at HarapanAnda Islamic Hospital, Tegal City was in the high category. There was a relationship between the level ofknowledge and compliance with taking medication in patients with pulmonary TB at Harapan Anda IslamicHospital, Tegal City. There was a relationship between the level of knowledge and compliance with takingmedication in patients with pulmonary TB at Harapan Anda Islamic Hospital, Tegal City. Patients who had goodknowledge tended to be more compliant in undergoing treatment. These results serve as input for health servicesto provide health service programs to improve knowledge and compliance with taking medication in patients withpulmonary TB better.

Acid mine drainage (AMD) is one of the major environmental problems arising from coal mining activities. AMD is formed through the oxidation of sulfide minerals, resulting in acidic water with high concentrations of dissolved heavy metals. This condition is characterized by elevated levels of Fe, Mn, and total suspended solids (TSS), which, if left untreated, can pollute nearby water bodies, damage aquatic ecosystems, and pose risks to human health. Therefore, effective, eco-friendly, and low-cost treatment methods are needed to minimize the negative impacts of AMD. This study aims to investigate the effect of activated carbon derived from sugarcane bagasse as an adsorbent for reducing Fe, Mn, and TSS levels in AMD at the sump of PT Alreksa Bara Mitra. The selection of sugarcane bagasse is based on its abundance as an agro-industrial waste and its high lignocellulosic content, making it a potential raw material for activated carbon. The research involved the preparation of activated carbon through carbonization and activation processes, followed by its application to AMD samples with variations in adsorbent dosage and contact time. Laboratory analyses were conducted to measure the concentrations of Fe, Mn, and TSS before and after treatment. The results showed that sugarcane bagasse-based activated carbon significantly reduced Fe, Mn, and TSS concentrations. The highest removal efficiencies were achieved under optimum conditions, reaching 93.14% for Fe, 95.05% for Mn, and 85.04% for TSS. These findings demonstrate that activated carbon from sugarcane bagasse has a strong adsorption capacity for dissolved metals and suspended solids in AMD. In conclusion, sugarcane bagasse-derived activated carbon has potential as an environmentally friendly and cost-effective alternative for AMD treatment, while simultaneously providing added value to agro-industrial waste. This research is expected to serve as a reference for the development of more sustainable mine wastewater treatment methods.

Indonesia is recognized as one of the world’s richest countries in terms of biodiversity, including a wide variety of traditional medicinal plants. One of the lesser-known yet promising local species is matoa (Pometia pinnata J.R. Forst & G. Forst), whose leaves have been traditionally used by local communities to treat various ailments, including diarrhea and seizures. This study aims to investigate the pharmacological effects of matoa leaf extract, with a particular focus on its anticonvulsant activity, while also reviewing its potential chemical constituents as a basis for herbal medicine development. The research was conducted using a combination of literature review and experimental testing on mice (Mus musculus) induced with strychnine to trigger seizures. Key observed parameters included seizure onset time and survival duration (dead time) following the administration of either synthetic drugs or matoa leaf extract. The results demonstrated that the matoa leaf extract exhibited significant anticonvulsant effects, as indicated by prolonged seizure onset and increased survival time in test animals. These pharmacological effects are presumed to be related to the presence of active compounds such as flavonoids, tannins, and alkaloids, which may contribute to the stabilization of the central nervous system. Compared to conventional synthetic anticonvulsants, matoa leaf extract may offer a safer, plant-based alternative with potentially fewer side effects. The findings of this study provide valuable scientific evidence supporting the potential of Pometia pinnata leaves in the development of Indonesian herbal phytopharmaceuticals. Furthermore, they highlight the importance of further research, including preclinical and clinical trials, to validate efficacy, determine optimal dosages, and ensure safety for human use.

This study aims to determine the effect of adding EM4 probiotics in various doses to commercial feed on the growth of jatimbulan tilapia (Oreochromis niloticus L). Probiotics are known to play a role in increasing digestive efficiency, nutrient absorption, and maintaining the health of the fish's digestive tract, so they are expected to support optimal growth. The research method used was a Completely Randomized Design (CRD) with four treatments, namely: P0 (control/without probiotics), P1 (5 ml EM4/kg feed), P2 (7 ml EM4/kg feed), and P3 (11 ml EM4/kg feed), each with four replications. The parameters observed were the growth in length and weight of jatimbulan tilapia during the maintenance period. The results showed that the administration of EM4 probiotics at certain doses was able to provide a significant effect on the growth of tilapia compared to the control treatment. Treatment P2 (7 ml/kg feed) provided the best growth results compared to other doses, both in terms of increasing length and body weight. Meanwhile, administering probiotic doses that are too low (P1) or too high (P3) tends to be less effective in supporting optimal growth. This is thought to be due to the disruption of the microbial balance in the digestive tract when the probiotic dosage is incorrect. This research provides useful information for Jatimbulan tilapia cultivation practices, particularly regarding the use of probiotics to increase growth efficiency. Using the correct probiotic dosage can be a strategy to increase the productivity and sustainability of freshwater fish farming.  

β-lactam antibiotics are a very important group of drugs and are most frequently used in the treatment of bacterial infections, both in healthcare facilities and for self-medication. The advantages of β-lactams lie in their effectiveness and broad spectrum of action. However, the development of pharmaceutical preparations containing β-lactams still faces significant challenges, particularly related to the physicochemical stability of these compounds. The reactive ring structure of β-lactams makes them highly susceptible to degradation, particularly through hydrolysis. This degradation process can be accelerated by various environmental factors such as high temperature, changes in pH, humidity, and the presence of certain excipients and solvents in drug formulations. This article comprehensively reviews the various factors that influence the stability of β-lactams, both in solid and liquid pharmaceutical dosage forms, as well as in microbiological media. Furthermore, it also examines various innovative formulation approaches that have been developed to improve the stability of these compounds. These approaches include film coating technology, encapsulation, and crystal engineering, which have been shown to reduce the rate of degradation and extend product shelf life. Literature studies have shown that solid dosage forms are generally more stable than liquid dosage forms, primarily because exposure to water and solvents can accelerate hydrolysis. Distribution and storage of these preparations are also important aspects to consider in maintaining the quality and effectiveness of β-lactam antibiotic therapy. Therefore, β-lactam product development requires a holistic approach, encompassing not only formulation and production technology but also optimal distribution and storage strategies. The use of appropriate analytical methods is also necessary to monitor degradation products and ensure product safety and effectiveness throughout the shelf life.

Infused water is a functional beverage made by soaking slices of fruits, vegetables, and herbs in mineral water to produce a natural flavor and enhance nutritional content. In recent years, infused water has become part of a healthy lifestyle trend due to its claimed benefits, including detoxification, improved hydration, and immune system enhancement. This article aims to review the latest scientific literature on the potential benefits of infused water on immune function, particularly in the context of regular consumption of natural ingredients such as lemon, ginger, strawberries, and herbs that are rich in vitamin C, antioxidants, and flavonoids. The review was conducted by searching scientific databases such as PubMed, Google Scholar, and ScienceDirect, using inclusion criteria that covered publications from 2020 to 2024. The findings indicate that infused water containing vitamin C, gingerol, and polyphenolic compounds can help improve immune function by reducing oxidative stress, suppressing inflammatory responses, and stimulating immune cell activity such as lymphocytes and macrophages. Furthermore, optimal hydration from infused water supports various physiological processes of the immune system. In conclusion, infused water holds potential as a simple, natural, and cost-effective strategy to support immune health. However, further research is needed to evaluate its efficacy, optimal formulations, and dosage for maximum benefit.