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Kartini Karim; Reny Retnaningsih

Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi 2025 LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Anxiety in laboring mothers is a psychological factor that can influence the course of labor, particularly during the second stage, and increase the risk of complications such as perineal rupture. Along with obstetric factors, the quality of labor guidance is crucial in preventing perineal trauma. This study aimed to analyze the relationship between maternal anxiety, labor guidance, and the incidence of perineal rupture at Obi Hospital, South Halmahera. Using an observational analytical design with a cross-sectional approach, the study involved 50 laboring mothers undergoing vaginal delivery, selected through purposive sampling. Data collection took place from February to April 2024, with maternal anxiety measured using a standardized anxiety questionnaire. Labor guidance and perineal rupture were assessed through observation sheets and clinical examinations. Data analysis was conducted univariately and bivariately using the Chi-Square test with a significance level of p < 0.05. The results showed a significant relationship between maternal anxiety and labor guidance (p < 0.05), as well as between maternal anxiety and perineal rupture (p < 0.05). Additionally, labor guidance was significantly associated with the incidence of perineal rupture (p < 0.05). Mothers with higher anxiety levels tended to receive poor labor guidance and had a higher risk of perineal rupture. The study concludes that maternal anxiety significantly impacts labor guidance and perineal rupture, emphasizing the need for holistic care that addresses both psychological and physical aspects of childbirth.

Ketut Ayu Lestari Windhradhi; Anny Eka Pratiwi; Dewa Ayu Putu Ratna Juwita

Jurnal Inovasi Riset Ilmu Kesehatan 2025 Pusat Riset dan Inovasi Nasional

Cervical cancer remains a major public health problem and is one of the leading causes of cancer-related mortality among women in Indonesia. Early detection through Visual Inspection with Acetic Acid (VIA) is an effective and feasible screening method at the primary health care level. However, the coverage of VIA screening among women of reproductive age (WRA) remains low. Knowledge is considered an important predisposing factor that may influence women’s motivation to undergo VIA screening. This study aimed to analyze the association between cervical cancer knowledge and motivation to undergo VIA screening among women of reproductive age. This study employed a quantitative analytic design with a cross-sectional approach. A total of 105 women of reproductive age were recruited using consecutive sampling at the Payangan Community Health Center, Gianyar Regency, Indonesia. Data were collected using validated and reliable structured questionnaires measuring cervical cancer knowledge and motivation to undergo VIA screening. Univariate analysis was performed to describe respondent characteristics, while bivariate analysis using the chi-square test was applied to examine the association between knowledge and motivation at a significance level of 5%. The results showed that 61.9% of respondents had good knowledge of cervical cancer, while 52.4% demonstrated low motivation to undergo VIA screening. A statistically significant association was found between cervical cancer knowledge and motivation to undergo VIA screening (p = 0.043). Women with higher levels of knowledge tended to have greater motivation to participate in VIA screening. In conclusion, cervical cancer knowledge is significantly associated with motivation to undergo VIA screening among women of reproductive age. These findings suggest that strengthening health education interventions at primary health care facilities is essential to enhance motivation and increase participation in early cervical cancer detection programs.

Irma Yunawati

Jurnal Inovasi Riset Ilmu Kesehatan 2025 Pusat Riset dan Inovasi Nasional

Adolescents are a vulnerable age group to nutritional problems due to increased nutritional requirements during periods of rapid growth. Suboptimal nutritional status, including undernutrition and anaemia, can negatively affect health and academic performance. This study aimed to describe the nutritional status of adolescents at SMA Negeri 2 Kendari, Southeast Sulawesi Province. This study employed a descriptive observational design conducted from August to September 2025 with a total sample of 226 twelfth-grade students’ selected using proportionate stratified random sampling. Data were collected through measurements of body weight and height to determine nutritional status based on the BMI-for-Age indicator and haemoglobin levels were assessed using a digital haemometer. Data were analyzed using univariate analysis. The results showed that most respondents had normal nutritional status (52.2%), while a considerable proportion were undernutrition (47.8%). In addition, more than half of the respondents were anaemia (50.9%). These findings indicate that although anthropometric nutritional status was generally normal, anemia remains a health problem that requires attention among adolescents. Regular monitoring of nutritional status and hemoglobin levels accompanied by nutrition education is recommended. Further studies are recommended to use an analytical study design to identify factors associated with nutritional status and anaemia.

Nando Yoga Pratama; Nurul Hafizah; Marlita Andhika Rahman

Jurnal Publikasi Ilmu Psikologi. 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

Drug abuse remains a serious problem in Indonesia, including in Jambi Province. Its effects are not only physical but also psychological, with aggressive behavior being one of the common consequences. Family support is considered a protective factor that can reduce aggression among inmates with a history of drug abuse. This study aims to describe family support, aggressive behavior, and the relationship between family support and aggressive behavior among inmates who are victims of drug abuse at Class II B Muara Sabak Prison. This research employed a quantitative approach with a correlational design and survey method. The sample was selected using purposive sampling, consisting of drug-related inmates at Class II B Muara Sabak Prison who met the inclusion criteria. The instruments used were the Family Support Scale and the Aggression Behavior Scale. Data were analyzed using correlation tests. The findings revealed a significant negative correlation between family support and aggressive behavior, with a correlation coefficient of r = -0.657. This indicates that higher family support is associated with lower levels of aggressive behavior, both physical and verbal. Family support plays an important role in reducing aggressive behavior among inmates with a history of drug abuse. Correctional rehabilitation programs are recommended to strengthen family involvement in consistently providing support.

Hajar Hajar; Hasnia Hasnia; Inez Vravty Lestari; Herawaty Herawaty; Sumarni Syam

Jurnal Inovasi Riset Ilmu Kesehatan 2025 Pusat Riset dan Inovasi Nasional

Low Birth Weight (LBW) is one of the leading causes of neonatal mortality and contributes to an increased risk of growth and developmental disorders in later life. Maternal nutritional status during pregnancy and the utilization of antenatal health services are important factors influencing fetal growth and development. Pregnant women with poor nutritional status are at higher risk of delivering low birth weight infants due to insufficient intake of essential nutrients required during pregnancy. In addition, inadequate utilization of antenatal care services may result in delayed detection and management of pregnancy-related complications. This study aimed to determine the relationship between maternal nutritional status and the utilization of health services with the incidence of LBW. The research employed an observational analytic design with a cross-sectional approach. The study population consisted of all women who delivered in the working area of Puskesmas X in 2026. A total of 80 respondents were selected using purposive sampling. Data were collected from maternal and child health (MCH) books and medical records and analyzed using the Chi-square test. The results showed a significant relationship between maternal nutritional status and the incidence of LBW (p=0.002), as well as between the utilization of health services and the incidence of LBW (p=0.004). It can be concluded that maternal nutritional status and compliance with antenatal visits are significantly associated with LBW, highlighting the need to improve nutritional monitoring and the quality of antenatal care services.

Wardah, Jihan Syalina; Nugroho, David Rizar; Ulya, Enden Darjatul; Mulyono, Mulyono

Jurnal Penelitian Komunikasi dan Sosialisasi 2025 Asosiasi Peneliti dan Pengajar Ilmu Sosial Indonesia

This study aims to analyze the influence of entertainment content consumption on TikTok toward the stress levels of university students. TikTok has become one of the most frequently used social media platforms among young adults, offering entertainment, distraction, and emotional relief. Meanwhile, academic stress is a common issue among students due to heavy coursework, deadlines, and pressure to perform. This research uses a quantitative method with a survey distributed to 100 active university students aged 18–24 who own a TikTok account and consume entertainment content such as comedy, challenges, and viral videos. Data were analyzed using descriptive statistics and simple linear regression. The results show that the overall frequency of using TikTok for entertainment is very high (mean = 4.26), while the level of academic stress also falls into the high category (mean = 4.06). Regression analysis indicates that TikTok entertainment content significantly affects students’ stress levels (p < 0.001). Result found is positive, meaning higher TikTok usage is associated with higher stress. The significance value based on the simple linear regression coefficient table is 0.000 < 0.05, so it can be concluded that the variable Use of TikTok Entertainment Content (X) has an effect on the variable Stress Levels Among Students (Y).

Nugraha, Arief Pambudi

Globe: Publikasi Ilmu Teknik, Teknologi Kebumian, Ilmu Perkapalan 2025 Asosiasi Riset Ilmu Teknik Indonesia

This literature study evaluates the accuracy of the Slope Mass Rating (SMR) method for coal mine slope stability in Indonesia through a systematic descriptive synthesis of 25 empirical studies from 2020 to 2025. The objectives of the study were to identify the level of SMR prediction accuracy, factors affecting the method's performance, and modifications required for local Indonesian conditions. The research method involved a systematic search with inclusion criteria for empirical studies reporting SMR and/or Safety Factor (SF) values ​​for coal mines and associated slopes in Indonesia. Quantitative analysis showed a range of reported SMR values ​​between 41 and 96 with a median of 72, while SF values ​​ranged from 1.137 to 4.09 for normal operational conditions. The synthesis results indicated that SMR provides a consistent stability classification for initial slope design and failure mode identification (planar, wedge, toppling), with historical validation showing a correlation of up to 91.23% between SMR-based hazard zoning and actual field events in some cases. Key limitations include dependence on discontinuity data quality, sensitivity to groundwater conditions and tropical weathering, and variation in the interpretation of adjustment factors F1-F4. Modifications such as NAAF23 and integration with numerical modeling have been shown to improve prediction reliability. It is recommended that coal mining practitioners combine SMR with kinematic analysis and limit equilibrium modeling as standard operating procedures, and develop adjustment factors specific to Indonesian geological conditions. Further research should focus on standardizing parameter reporting and cross-site quantitative validation to enable more robust statistical meta-analyses.  

Izmi Arisa Putri Lubis; Athira Demitri; Winda Sauci Br Panjaitan; Vania Amanda; Dhea Syafitri +1 more

Sevaka : Hasil Kegiatan Layanan Masyarakat 2025 STIKES Columbia Asia Medan

Iron Deficiency Anemia is a common health problem among adolescents, particularly females, and is associated with decreased concentration, fatigue, and reduced academic performance. This community service program aimed to increase students’ awareness and knowledge regarding early detection of anemia symptoms (5L) and the adoption of iron-rich dietary practices. The intervention was conducted through interactive health education sessions involving lectures, discussions, and questions and answers with 30 students of MAN Batubara. The results indicated an improvement in students’ understanding of anemia symptoms, early behavioral changes in choosing iron-rich foods, and the emergence of local student leaders who supported peer awareness. This participatory educational approach proved effective in enhancing nutritional literacy and collective awareness toward anemia prevention among adolescent

Faridah Hanum Rajagukguk; Nurmaini Nurmaini; Taufik Ashar

International Journal of Health and Medicine 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

Acute Respiratory Infections (ARI) in the working area of Mulyorejo Public Health Center, where an aluminum factory is located, rank first among the ten most common diseases. This study aims to analyze the influence of sociodemographic characteristics and PM2.5 exposure on ARI complaints in the aluminum factory area of Payageli Village, Deli Serdang Regency. The cross-sectional observational study involved 160 housewives living within a radius of 10–1500 meters from the factory’s chimney. The analysis included univariate, bivariate, and multivariate methods. Results showed that 58.1% of respondents experienced ARI symptoms in the past month. The average ambient (outdoor) PM2.5 concentration measured from three sampling points was 12.3 µg/m³, which did not exceed the WHO standard (<15 µg/m³). The highest concentration was recorded in the southern direction (15.5 µg/m³). Bivariate analysis indicated that education (p = 0.010), direction of house location (p = 0.001), and indoor PM2.5 concentration (p = 0.006) were significantly associated with ARI. Multivariate logistic regression analysis showed that the most dominant factor influencing ARI was indoor PM2.5 concentration (p = 0.039), followed by education (p = 0.013) and direction of house location (p = 0.001). This study provides a scientific basis for air quality control and housing environment improvement to reduce the risk of environmentally related diseases in industrial zones.

Sayed Zakariya Habib; Mohammad Ali Fahimi; Mir Mohammad Naim Sadat

International Journal of Information Engineering and Science 2025 Asosiasi Riset Teknik Elektro dan Infomatika Indonesia

This study aims to investigate the integration of information systems and the associated security challenges within Afghanistan's current market, emphasizing the complex relationship between technological innovation, governance stability, and institutional readiness. Using the Delphi method, the study engaged experts from academia, government, and the private sector to identify key barriers and enablers shaping Afghanistan's digital transformation. Findings reveal that the country's progress in adopting information systems is hindered by fragmented policies, weak cybersecurity awareness, infrastructure limitations, and dependency on donor-funded projects. Despite growing recognition of the importance of digitalization, Afghanistan's institutional fragility continues to impede coordinated implementation and sustainable innovation. Comparative insights with other emerging markets highlight that long-term investment in digital literacy, regulatory coherence, and private sector engagement are critical to overcoming these barriers. The study highlights the importance of adopting a hybrid developmental model that harmonizes local institutional realities with internationally recognized technological standards, fostering adaptability and resilience within Afghanistan's volatile environment. It advances existing understanding by demonstrating how governance reform, human capital enhancement, and cybersecurity integration function as mutually reinforcing components of the nation's digital transformation. Sustainable progress depends on establishing a unified national vision that bridges technology, education, and governance, thereby reinforcing market integrity and institutional stability amid persistent security and economic uncertainty.

Sri Rahayu; Dwi Retnaningsih

Jurnal Kesehatan dan Kedokteran 2025 Lembaga Pengembangan Kinerja Dosen

Low Birth Weight (LBW) infants are among the leading causes of neonatal morbidity and mortality in Indonesia. This condition is associated with the immaturity of organ systems, including thermoregulation and respiratory function, making infants prone to stress, hypothermia, and oxygenation problems. One nursing intervention that helps improve physiological stability is the nesting technique, which positions the baby similarly to the intrauterine condition using soft rolled cloths as a “nest.” This case study aimed to determine the effect of nesting on oxygen saturation and pulse frequency changes in LBW infants in the perinatology room of RSUD Batang. The design used a descriptive case study with a nursing process approach involving 5 LBW infants who met inclusion criteria. The intervention was carried out by applying nesting for 30 minutes, then measuring oxygen saturation and pulse rate before and after the intervention using a pulse oximeter. The results showed an increase in oxygen saturation and changes in pulse rate after nesting. The mean oxygen saturation before intervention was 94%, increasing to 98% after three days of treatment. The average pulse rate increased from 130 beats/minute to 136 beats/minute, remaining within normal physiological limits (120–160 bpm). This indicates improved comfort and physiological stability due to the flexed position during nesting, which reduces stress and enhances oxygen efficiency. In conclusion, the nesting technique effectively improves oxygen saturation and stabilizes pulse rate in LBW infants. It is recommended as an evidence-based nursing practice for promoting comfort and physiological stability in premature or LBW infants in perinatology units.    

Imroatus Sholikhah; Yuyun Nailufar

Jurnal Riset Ilmu Farmasi dan Kesehatan 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

Tomato (Solanum lycopersicum) extract is known to contain potent antioxidant compounds such as lycopene, vitamin C, and flavonoids that can protect reproductive cells from oxidative stress. This study aims to analyze the effectiveness of tomato extract in improving the quality of spermatozoa in white rats (Rattus norvegicus) exposed to cigarette smoke, which is a major source of free radicals. The research applied a literature review approach by identifying, selecting, and analyzing related studies published between 2013 and 2023 from the Google Scholar and Academia.edu databases. Ten eligible studies were included for synthesis. The results show that the administration of tomato extract at doses ranging from 20 to 60 mg/kgBW/day significantly increased sperm motility, morphology, and viability in rats exposed to cigarette smoke. The improvement was associated with the antioxidant effect of lycopene, which protects Leydig cells and maintains testosterone production. These findings suggest that tomato extract has significant potential as a natural antioxidant therapy to prevent oxidative damage and reproductive disorders caused by cigarette smoke exposure.

Karningsih Karningsih; Mardeyanti Mardeyanti; Dewi Nirmala Sari; Ni Gusti Made Ayu Agung Budhi

International Journal of Health and Medicine 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

This study aimed to examine the relationship between maternal anxiety levels and the timing of Early Initiation of Breastfeeding (EIBF) among primiparous mothers. EIBF, also known as Inisiasi Menyusu Dini (IMD), is a vital procedure that supports the establishment of effective breastfeeding and is recommended globally. Nevertheless, various maternal factors, particularly psychological conditions, may influence the implementation of EIBF. The main objective of this research was to determine whether increased anxiety during the peripartum period is associated with delays in initiating breastfeeding. A correlational analytic design with a cross-sectional approach was utilized in this investigation. The study population consisted of 77 eligible participants, while the final sample included 69 primiparous mothers who met the inclusion and exclusion criteria. Participants were chosen through purposive sampling. The independent variable was the maternal anxiety level, and the dependent variable was the timing of EIBF implementation. Data were gathered using a structured self-administered questionnaire designed to measure both variables. Statistical analysis was conducted using the Mann-Whitney U test. The findings demonstrated a p-value of 0.0389, which was below the significance threshold of 0.05 (p < 0.05), indicating the rejection of the null hypothesis. Therefore, the results revealed a significant relationship between anxiety levels and the timing of EIBF among primiparous mothers. Elevated anxiety was identified as a factor contributing to delayed initiation of breastfeeding. These findings highlight the importance of regular psychological screening and effective anxiety management for first-time mothers during childbirth to facilitate optimal postnatal care, particularly the timely initiation of EIBF.

H. Subagyo; Bintang Paula Putra; Zairin Zairin; Aminudin Aminudin; Wawan Wawan

Prosiding Seminar Nasional Ilmu Manajemen Kewirausahaan dan Bisnis 2025 Asosiasi Riset Ilmu Manajemen Kewirausahaan dan Bisnis Indonesia

This study aims to determine the influence of brand awareness, brand association, and brand loyalty associated with brand equity on consumer purchase decisions in using GO-JEK services in Depok City. These three variables were analyzed both partially and simultaneously to identify the degree of their influence on consumers' decisions in choosing online transportation services. The research method used is a quantitative approach with the distribution of questionnaires as a data collection instrument, while the analysis is carried out using inferential statistical techniques. The results show that partially the variables of brand association and brand loyalty have a significant and dominant influence on purchasing decisions. This indicates that consumers' perception of the image and emotional connection with the GO-JEK brand plays an important role in the decision to choose the service. In addition, the results of the simultaneous test showed that brand awareness, brand association, and brand loyalty together had a positive and significant influence on purchasing decisions. These findings confirm that strong brand equity is an important factor in increasing consumer interest and preference for GO-JEK services. Therefore, companies need to maintain and strengthen branding strategies to increase competitiveness and maintain customer loyalty.

Ratna Puri; Natsir Nugroho; Duta Liana

International Journal of Health and Medicine 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

Background: Patient safety culture forms the cornerstone of safe and high-quality healthcare delivery. However, its implementation often encounters barriers, particularly the persistence of a blaming culture that discourages staff from reporting patient safety incidents. Clinical leadership and the intensity of incident reporting are believed to play a pivotal role in shaping and sustaining a positive patient safety culture.Objective: This study aims to examine the influence of clinical leadership and patient safety incident reporting intensity on patient safety culture, with blaming culture serving as an intervening variable at Sentra Medika Cikarang Hospital.Methods: A quantitative research approach with an explanatory design was applied. The study involved 147 nurses selected through stratified random sampling. Data were collected using structured questionnaires and analyzed using Structural Equation Modeling (SEM) with the Partial Least Squares (PLS) method to test the direct and indirect relationships among variables. Results: The findings revealed that both clinical leadership and incident reporting intensity significantly influence patient safety culture, both directly and indirectly, through the mediation of blaming culture. Strong clinical leadership and a high level of incident reporting were associated with a more positive patient safety culture, while a high blaming culture weakened this relationship. Conclusion: The study underscores the importance of fostering supportive clinical leadership and cultivating a non-punitive reporting environment to strengthen patient safety culture. Hospital management should focus on leadership development and the creation of open, blame-free communication systems to enhance safety outcomes.

Hayatul Firda; Khaira Rizki; M. Daud

Jurnal Ilmu Kesehatan 2025 Lembaga Pengembangan Kinerja Dosen

Although often overlooked by society, mental health is a crucial component of overall health. One of the biggest barriers to managing mental health is the societal stigma associated with People with Mental Disorders (ODGJ). High stigma can lead to negative perceptions that hinder the healing process of those suffering from mental illness. The purpose of this study was to determine how societal perceptions of individuals with mental illness in Cot Rumpun Village, Aceh Besar Regency, relate to societal stigma. This study used a cross-sectional methodology and a descriptive analysis design. Seventy respondents were selected for the study sample using a direct random selection method. The Community Attitudes Against Mentally Ill (CAMI) questionnaire measured public sentiment, and the Perception of Discrimination and Devaluation (PDD) questionnaire measured stigma. Chi-square tests were used in univariate and bivariate data analysis. The majority of respondents expressed positive attitudes toward those with mental health problems (60.0%), while low stigma toward those with mental disorders (54.3%). The results of the Chi-Square test indicate a significant relationship between community stigma and community attitudes towards people with mental disorders (ODGJ) with a value of ρ = 0.000 (ρ <0.05). Health workers are expected to conduct routine counseling and psychoeducation to the community about mental health, including how to deal with, support people with mental disorders appropriately, reducing stigma in the community environment. Local governments and community leaders are also expected to play an active role in creating an inclusive, supportive, discrimination-free social environment for people with mental disorders (ODGJ).

Ferlita Ferlita; Fauziah Fauziah; Mansuriza Mansuriza

Jurnal Ilmu Kesehatan 2025 Lembaga Pengembangan Kinerja Dosen

Research at Diponegoro University found that 66.7% of 63 respondents experienced neck pain due to using a laptop for more than 4 hours. Prolonged laptop use can negatively impact health from an ergonomic perspective, as the recommended maximum usage is 2 hours per day. However, students often maintain non-ergonomic positions for extended periods. This study aimed to determine the relationship between laptop use and neck pain among Diploma Three Nursing Students at Abulyatama University, Aceh. The research utilized an analytical, cross-sectional design, with a population of 556 students and a sample of 85 students, selected through purposive random sampling. The research was conducted at Abulyatama University from May 15 to June 2, 2025, and data was collected using a questionnaire with a Numeric Rating Scale. Analysis involved both univariate and bivariate methods using the Chi-Square test. The results showed that among 85 respondents, 44 (95.7%) experienced moderate pain, 8 (40.0%) had mild pain, and 8 (42.1%) reported severe pain. Statistical analysis indicated a significant correlation (p=0.000) between laptop use and neck pain. In conclusion, there is a strong relationship between laptop use and complaints of neck pain among university students. The research is expected to raise student awareness about the health risks associated with prolonged and improper laptop use, encourage better posture, and serve as a reference about limiting laptop use and improving ergonomics.

Husnassabil, Ahmad Hadin; Marjuki, Marjuki; Susilorini, Tri Eko; Kuswati, Kuswati; Surjowadojo, Puguh +3 more

JAPSI (Journal of Agriprecision and Social Impact) 2025 CV. Komunitas Dunia Peternakan

This study aimed to evaluate the forage production characteristics of Japanese papaya (Cnidoscolus aconitifolius) as a potential feed source for ruminant livestock. The research employed a case study approach through direct field observations on four mature Japanese papaya plants naturally grown as living fences in Malang City. Measured variables included the diameter of the main branch, number and length of sub-branches, forage yield, and nutrient composition. Data were analyzed using correlation and simple linear regression to determine the relationship between plant structure and forage productivity. The results indicated that the diameter of the main branch showed a strong positive correlation with the number and length of sub-branches, as well as with forage yield and nutrient content (DM, OM, CP, CF, and EE). Regression analysis confirmed that larger branch diameters were consistently associated with higher forage production and better nutrient values. These findings suggest that the diameter of the main branch can serve as a reliable indicator for estimating the forage yield and nutritional potential of Japanese papaya, providing a practical tool for its use in sustainable ruminant feed management.

Madnur Soleh; Dwi Retnaningsih

Jurnal Ilmu Kesehatan 2025 Lembaga Pengembangan Kinerja Dosen

Malaria is a global health problem, especially in tropical countries like Indonesia. Papua, with 14,586 cases, and Jayapura City in 2023 had 29,938 cases. This is due to nocturnal activities, knowledge, and preventive measures, which contribute to the high incidence of malaria. The purpose of this study was to identify factors associated with malaria incidence at Bhayangkara Hospital Class II, Jayapura. This research was an analytical study with a cross-sectional design. Data collection was conducted using a questionnaire. A total of 82 respondents were recruited using a simple accidental sampling technique. The data obtained were statistically analyzed using the chi-square test. Based on the analysis results, it was found that of the 82 respondents, the characteristics of the respondents were mostly aged > 20 years (74 people (90.2%), male (48 people (58.5%) and unemployed (53 people (64.6%). There was a significant relationship between nighttime activities and malaria incidence at Bhayangkara Hospital Level II Jayapura. (p-value 0.015 <α (0.05). There was a significant relationship between knowledge and malaria incidence at Bhayangkara Hospital Level II Jayapura (p-value 0.000 <α (0.05). There was a significant relationship between malaria prevention measures and malaria incidence at Bhayangkara Hospital Level II Jayapura (p-value 0.008 <α (0.05). Nighttime activities, knowledge and malaria prevention measures were significantly associated with malaria incidence.

Hiba Hazim Hamid; Kais Kassim Ghaima

Jurnal Riset Ilmu Farmasi dan Kesehatan 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

Importance of gut microbiota during neurodevelopment has increased, as has the potential relationship between the gut microbiota and (ASD). Complex associations between gut microbiota and ASD are explored here, including significant pathways such as immune modulation, neurotransmitter control, and gut-brain axis signaling. Based on available data, individuals with ASD possess distinctive microbial signatures that are characterized by reduced diversity and altered abundance of specific bacterial species. Such modifications could be related to symptoms of the behavioral nature, neuroinflammatory, as well as gastrointestinal. ASD growth as well as severity could be influenced by the composition of microbiome, depending on genetic, nutrition, microbial exposure during the earliest phases, as well as antibiotic use. Additional therapies based on the microbiome that presented the potential to alleviate the symptoms related to ASD include the use of probiotics, prebiotics, diet modification, as well as fecal microbiota transplantation (FMT). Still, establishing the causal associations, standardizing the procedure of handling the patients, as well as solving the problem related to the manipulation of microbiome, are still challenging activities, though. Large-scale, long-term studies need to be the core agenda of subsequent research, so that specific microbial signatures associated with ASD will be clearly defined, as well as tailored therapies that address the microbiome will be developed. Understanding more about the role that the microbiota plays during ASD may open up the diagnosis as well as the therapy based on the entirely new concepts, something that will ultimately benefit the patients who possess the disorder.