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This explanatory research aims to know the effect of self acceptance and emotional regulation to predict psychological well being cancer patient and to find which one is more effective to predict psychological well being cancer patients. The sampling technique used in this research was convenience sampling technique. Subjects in this research is 100 cancer patient at Dr Cipto Mangunkusumo National Central Public Hospital Jakarta. Data collection was carried out through questionnaires, interviews and observation. Self report technique is used in collecting instrumen data. The data analysis technique used is multiple linear regression analysis processed using Statistical Package for the Social Sciences (SPSS) software. The result shows that there is an influence between self acceptance and emotional regulation  in predicting psychological well being where the score of p value F test is 0,000 (p<0,05) and it is found that self acceptance  is more effective in predicting psychological well being compare with emotional regulation  Based on the research results, the findings are as follows: (1) collectively or simultaneously self acceptance and emotional regulation has a positive and significant effect on psychological well being, (2) partially self acceptance has a positive and significant effect on psychological well being; (3) partially emotional regulation has a positive and significant effect on psychological well being.

This study examines postpartum nursing care for mothers undergoing Sectio Caesarea (SC) with the primary nursing diagnosis of ineffective breastfeeding. The purpose is to evaluate the effectiveness of oxytocin massage intervention in improving breastfeeding outcomes in post-SC mothers. The study was conducted in Mawar Ward, RSUD dr. H. Soewondo Kendal, involving four patients experiencing delayed lactation, difficulty in baby latching, and psychological challenges such as anxiety and lack of confidence. The intervention was based on the Indonesian Nursing Intervention Standards (SIKI), focusing on observation, therapeutic actions, education, and collaboration with healthcare teams and family members. Oxytocin massage was performed 2–3 times daily, complemented by warm compresses, breastfeeding position training, and emotional support. The results indicated significant improvements: increased breast milk production, better baby latching, reduced maternal anxiety, and higher self-confidence in breastfeeding. This evidence-based approach highlights that comprehensive postpartum nursing care—integrating physical, psychological, and family support—plays a crucial role in ensuring breastfeeding success and overall maternal recovery after SC.

Type 2 Diabetes Mellitus is a chronic disease that not only causes physical disorders, but also has an impact on the patient's psychological condition, especially increased stress levels. Unmanaged stress can worsen medical conditions, decrease adherence to treatment, and negatively impact the patient's quality of life. Social support is known to have an important role as a protective factor in helping patients cope with psychological burden. This study aimed to analyze the relationship between social support and stress levels in patients with Type 2 Diabetes Mellitus. The research design used was descriptive correlation with a cross-sectional approach, involving [number of respondents] patients selected with the [mention sampling technique]. The research instrument used a validated social support questionnaire and stress scale. The data were analyzed by the Pearson/Spearman correlation test according to the data distribution. The results showed that there was a significant relationship between social support and stress levels in patients with Type 2 Diabetes Mellitus (p < 0.05), with a negative correlation direction, which means that the higher the social support received by the patient, the lower the level of stress experienced. These findings confirm the importance of the role of family, health workers, and the social environment in supporting patients to manage stress and improve quality of life. This study recommends the need for social support-based interventions in diabetes management programs in health services.

The surgery often causes anxiety, which has an impact on physical and psychological conditions of preoperative patients. The data from WHO shows that 50% patients all over the world experienced anxiety, where 5-25% patients are between 5 and 20 years old, and 50% patients are 55 years old. Pre-operational anxiety reaches 534 million patients. Many factors affect anxiety in patients, including family support. This study aims to acknowledge the correlation between family support and anxiety of post-surgery patients in Meuraxa Regional General Hospital, Banda Aceh. This study employs an analytical correlational method with a cross-sectional approach by involving 51 patients selected using an accidental sampling technique. A family support questionnaire is adopted from Nurwulan, with a Cronbach's alpha 0.856. The questionnaire of anxiety using the APAIS scale of Cronbach's alpha 0.825. Univariate and bivariate analysis using the chi-square test. The results indicate that among 51 respondents, the level of anxiety is in a medium state, as 26 respondents (51.0%), family support is in the high category, 47 respondents (92.2%), with a P-value 0.026 (P-value < 0.05). In conclusion, there is a significant relationship between family support and preoperative anxiety at Meuraxa General Hospital Banda Aceh. Families are expected to continuously provide emotional, informational, instrumental, and appraisal support so that patients feel calmer, are able to reduce excessive anxiety, and are better prepared to undergo surgery.

Chronic kidney disease (CKD) patients undergoing hemodialysis are at risk of experiencing intradialytic complications, one of which is hypertension. Management of hypertension in hemodialysis units is generally pharmacological, although non-pharmacological interventions may serve as an effective, simple, and safe complementary option. One such technique is Benson relaxation, which combines controlled deep breathing with spiritual elements to reduce sympathetic activity and promote relaxation. This case study to determine the effect of Benson relaxation therapy on blood pressure of intradialytic hypertension patients at RSUD Batang. The case study design was a case study involving 5 CKD patients undergoing hemodialysis. The intervention was performed by guiding patients to practice Benson relaxation for about 10–15 minutes, with blood pressure measured before and after the intervention using a digital sphygmomanometer. The results showed a decrease in blood pressure in most respondents. The average systolic blood pressure decreased from 153.4 mmHg to 145.6 mmHg, while diastolic pressure decreased from 92.4 mmHg to 87.6 mmHg. In addition to physiological improvement, patients also reported subjective relief such as reduced dizziness, palpitations, and tension. In conclusion, Benson relaxation therapy proved effective in reducing blood pressure among intradialytic hypertension patients. This intervention can be recommended as a complementary non-pharmacological therapy in nursing care to improve comfort in hemodialysis patients.  

Hypertension is categorized as one of the most widespread chronic non-infectious conditions among the elderly and can heighten the risk of serious complications. A non-pharmacological strategy that may be implemented to manage hypertension is the administration of boiled moringa leaves (Moringa oleifera), which are known among scientific communities for possessing antioxidant agents and potent bioactive molecules that function synergistically in maintaining cardiovascular stability and decreasing arterial pressure. This empirical study sought to examine how far the intake of boiled moringa leaves contributes to reducing blood pressure values in hypertensive older adults living within Meunasah Papeun Village, situated in Krueng Barona Jaya Subdistrict, Aceh Besar District. The statistical evaluation showed a significant p-value of 0.001 (p < 0.05), confirming a substantial effect under a quantitative quasi-experimental approach applying the One Group Pretest-Posttest model. The research sample included 20 participants chosen from a total population of 77 individuals through purposive sampling. The investigation took place from May 27 to June 25. Data were obtained using observation forms, standard operating procedures (SOP) for moringa leaf preparation, and manual sphygmomanometer readings. The findings revealed that prior to the application of treatment, the mean systolic blood pressure reached a level of 193.30 mmHg, whereas following the intervention it displayed a considerable decrease, it fell to 129.75 mmHg. The mean diastolic pressure also exhibited a decrease from 94.00 mmHg, confirming the notable influence of moringa leaf decoction in controlling hypertension. In summary, moringa leaf infusion proved effective in lowering blood pressure among elderly individuals suffering from hypertension. It is recommended that patients regularly consume boiled moringa leaves when experiencing increased blood pressure, that community health services provide education regarding non-pharmacological hypertension management through moringa leaf decoction, and that further research explore this topic with broader variables.

Sectio caesarean surgery is a surgical procedure that can effectively prevent ma- ternal and newborn deaths when used for reasons of medical indications. Post operative sectio caesarean can pose several risks of complications, one of which is pain and surgical wound infection. Non pharmacological approach aromatherapy as a complementary therapy to reduce postpartum pain. This case study aims to analyze the influence aromatherapy lavender on reducing pain levels in post sectio caesarean mothers by using the case study method pre and post test. The case study was carried out in 25 May 2025 – 07 June 2025. This type of case study is descriptive with the number of subjects used, namely three post partum mothers in the RSUD Batang private sector with pain assessment using a questionnaire Numeric Rating Scale (NRS). The results of the case study showed a change in pain intensity from a scale of 6-7 to a scale of 4-5. This shows an influence aromatherapy lavender on reducing pain levels in postpartum mothers caesarean section Giving innovation aromatherapy can be used as an independent nursing in- tervention so that it can be applied to patients regularly.

Malaria is a global health problem, especially in tropical countries like Indonesia. Papua, with 14,586 cases, and Jayapura City in 2023 had 29,938 cases. This is due to nocturnal activities, knowledge, and preventive measures, which contribute to the high incidence of malaria. The purpose of this study was to identify factors associated with malaria incidence at Bhayangkara Hospital Class II, Jayapura. This research was an analytical study with a cross-sectional design. Data collection was conducted using a questionnaire. A total of 82 respondents were recruited using a simple accidental sampling technique. The data obtained were statistically analyzed using the chi-square test. Based on the analysis results, it was found that of the 82 respondents, the characteristics of the respondents were mostly aged > 20 years (74 people (90.2%), male (48 people (58.5%) and unemployed (53 people (64.6%). There was a significant relationship between nighttime activities and malaria incidence at Bhayangkara Hospital Level II Jayapura. (p-value 0.015 <α (0.05). There was a significant relationship between knowledge and malaria incidence at Bhayangkara Hospital Level II Jayapura (p-value 0.000 <α (0.05). There was a significant relationship between malaria prevention measures and malaria incidence at Bhayangkara Hospital Level II Jayapura (p-value 0.008 <α (0.05). Nighttime activities, knowledge and malaria prevention measures were significantly associated with malaria incidence.

Obstetricians are often confronted with medical malpractice lawsuits, even when they have acted in accordance with professional standards, medical service standards, operational procedures, and medical ethics. Medical malpractice is generally defined as negligence or deviation from professional standards that results in serious harm to patients (Fiscina, 1999). This study aims to examine the application of the concept of medical malpractice along with its legal implications and to analyze the forms of legal protection available to obstetricians under Law Number 17 of 2023 on Health, viewed from the perspective of the principle of justice. Using a normative juridical method with descriptive-analytical specifications, the research employed a literature study and qualitative deductive analysis. The results indicate that legal protection for obstetricians consists of two dimensions: preventive and repressive. Preventive protection includes the implementation of informed consent, proper medical records, and compliance with standard operating procedures. Repressive protection involves legal defense mechanisms and institutional or professional organizational support. However, this protection remains suboptimal, as the decisions of the Indonesian Medical Disciplinary Board (MKDKI) are not always taken into account by the courts (Rahman, 2022). From the perspective of Rawls’ principle of justice, protection for obstetricians should ensure a balanced recognition of both patients’ and doctors’ rights, thereby promoting fairness and equitable justice for all parties (Rawls, 1971).

This study aims to analyze the application of the doctrine of vicarious liability in the liability of hospitals for medical malpractice lawsuits in Indonesia. The increasing number of medical disputes raises questions regarding the extent to which hospitals can be held responsible for the negligence of medical personnel working under their authority. This research employs a normative juridical method with statutory, conceptual, and case approaches, by examining the Indonesian Civil Code, Law No. 44 of 2009 on Hospitals, Law No. 17 of 2023 on Health, and relevant court decisions. The findings reveal that, normatively, hospitals can be held accountable under Article 1367 of the Civil Code, which aligns with the doctrine of vicarious liability (Black, 2019). However, judicial practice in Indonesia remains inconsistent: in some cases judges place liability on hospitals, while in others they hold individual doctors fully responsible (Budiman, Absori & Rizka, 2023; Vitrianingsih, Miarsa & Yahya, 2025). This inconsistency demonstrates a gap between normative regulation and juridical implementation. The novelty of this study lies in emphasizing the importance of the principle of justice in applying vicarious liability. Legal protection should not be limited to written norms but must also be substantive by balancing patients’ rights to safe and quality healthcare with the rights of medical personnel and hospitals to legal certainty. This is in line with Rawls’ (1971) concept of justice as fairness and Radbruch’s (2006) idea of balancing justice, legal certainty, and expediency.

Knee osteoarthritis is one of the most prevalent musculoskeletal disorders in the elderly, characterized by progressive degeneration of articular cartilage, chronic pain, joint stiffness, and reduced functional capacity. In Indonesia, the prevalence of knee osteoarthritis is notably high, affecting over 30% of individuals aged above 60 years. This condition leads to significant health burdens, impaired quality of life, and increased economic costs. Non-pharmacological management strategies such as hydrotherapy and quadriceps exercise are widely recommended to relieve pain and improve joint function. Hydrotherapy utilizes the physical properties of water including buoyancy, hydrostatic pressure, viscosity, and warmth to reduce joint loading, enhance circulation, and promote relaxation. Quadriceps exercise, on the other hand, focuses on strengthening the quadriceps muscle to stabilize the knee joint, thereby reducing pain and improving functionality. The combination of these two interventions is expected to provide greater benefits than a single modality. Research Design: This study employed a quasi-experimental design with a one-group pre-post test approach on 12 elderly respondents with knee osteoarthritis at OSF Magdalena Daemen BSB Convent. Pain was measured using the Visual Analogue Scale (VAS) before and after the intervention, which consisted of hydrotherapy and quadriceps exercise administered twice a week for four weeks. Results: The findings showed a decrease in the mean pain score from 4.42 to 3.08, with the Wilcoxon test yielding p = 0.001 (p < 0.05), indicating a significant difference in pain levels before and after the intervention. Conclusion: The combination of hydrotherapy and quadriceps exercise is effective in reducing pain in patients with knee osteoarthritis.

Importance of gut microbiota during neurodevelopment has increased, as has the potential relationship between the gut microbiota and (ASD). Complex associations between gut microbiota and ASD are explored here, including significant pathways such as immune modulation, neurotransmitter control, and gut-brain axis signaling. Based on available data, individuals with ASD possess distinctive microbial signatures that are characterized by reduced diversity and altered abundance of specific bacterial species. Such modifications could be related to symptoms of the behavioral nature, neuroinflammatory, as well as gastrointestinal. ASD growth as well as severity could be influenced by the composition of microbiome, depending on genetic, nutrition, microbial exposure during the earliest phases, as well as antibiotic use. Additional therapies based on the microbiome that presented the potential to alleviate the symptoms related to ASD include the use of probiotics, prebiotics, diet modification, as well as fecal microbiota transplantation (FMT). Still, establishing the causal associations, standardizing the procedure of handling the patients, as well as solving the problem related to the manipulation of microbiome, are still challenging activities, though. Large-scale, long-term studies need to be the core agenda of subsequent research, so that specific microbial signatures associated with ASD will be clearly defined, as well as tailored therapies that address the microbiome will be developed. Understanding more about the role that the microbiota plays during ASD may open up the diagnosis as well as the therapy based on the entirely new concepts, something that will ultimately benefit the patients who possess the disorder.

The high number of hypertension cases is due to the still low level of hypertension control, specifically medication adherence. Treatment adherence is crucial for maintaining health and well-being in patients with hypertension. In contrast, non-adherence to medication leads to treatment failure. This study aims to determine the relationship between self-management and adherence to hypertension medication in the elderly. This research employed an analytical design with a cross-sectional approach. The study consisted of 49 elderly people with hypertension in Cot Cut Village, Kuta Baro, Aceh Besar. The sample was chosen using a total sampling technique. The MMAS-8 questionnaire was used to assess adherence to hypertension medication with a Cronbach's alpha of 0.860. The self-management questionnaire showed a Cronbach's alpha of 0.766. The research was conducted from April 8th to 14th, 2025. The data analysis used univariate and bivariate methods, using the chi-square test. The results showed that out of 49 respondents, 21 (42.9%) were less adherent to hypertension medication, and 29 (59.2%) had less adherence to self-management. The chi-square test indicated a p-value of 0.001, showing a relationship between self-management and adherence to hypertension medication among the elderly. This research suggests that hypertensive patients should be supervised to improve medication adherence and self-care management to maintain stable blood pressure.

Impaired emotion regulation and decreased quality of life are common, yet often untreated, sequelae of stroke. Conventional rehabilitation primarily targets physical and cognitive recovery, leaving affective disturbances unaddressed. This study examined the efficacy of a structured Buddhist meditation program—Mindful Resilience After Stroke (MRAS)—for improving emotion regulation and quality of life in stroke survivors. Forty-two ischemic/hemorrhagic stroke patients (3–18 months post-onset) were consecutively recruited and randomly allocated to an intervention group (n = 21) receiving an 8-week MRAS protocol (1 × 60 min/week) or a control group (n = 21) receiving standard care only. Emotion regulation was assessed with the Difficulties in Emotion Regulation Scale-Short Form (DERS-SF) and quality of life with the Stroke-Specific Quality of Life Scale (SS-QOL). Between-group changes (Δ post-pre) were analyzed using independent t-tests or Mann–Whitney U tests (α = 0.05). The intervention group showed a significantly greater reduction in emotion-regulation difficulties than controls (ΔDERS-SF −18.4 ± 5.1 vs. −3.2 ± 4.3; p < 0.001; d = 1.62). Quality-of-life gains were also larger in the intervention group (ΔSS-QOL 35.7 ± 8.9 vs. 7.1 ± 6.5; p < 0.001; d = 1.89). The most improved sub-domains were emotional acceptance, emotional awareness, and impulse control (DERS-SF), as well as energy, mood, and social participation (SS-QOL). No intervention-related adverse events were reported. MRAS is an effective and safe adjunctive intervention to enhance emotion regulation and quality of life after stroke. Embedding mindfulness practices grounded in Buddhist tradition into stroke rehabilitation offers a holistic, culturally adaptable approach for neuropsychological services in Indonesia.

The umbilical cord is the main entry point for systemic infection in newborns. Umbilical cord care aims to prevent infection and accelerate the breaking of the umbilical cord. Some postpartum mothers have insufficient knowledge about umbilical cord care so that education is needed. This study aims to determine the effect of education on newborn umbilical cord care on postpartum mothers' knowledge. This research method is a quantitative pre-experimental study using the One Group Pre Test-Post Test without control approach. The study was conducted at RSIA Murni Teguh Rosiva Medan. The population was 101 patients per month and 47 samples were obtained. Sampling was done randomly. Analysis was carried out univariately in a frequency distribution table and bivariately using the Paired Sample T-Test because the data was normally distributed. The results of the study showed that before being given education (pretest) the majority of postpartum mothers had poor knowledge (53.2%) with an average value of 5.09 ± 1.501, after being given education (posttest), the majority of postpartum mothers had good knowledge (70.2%) with an average value of 8.19 ± 1.096. Providing education on newborn umbilical cord care had a significant effect on increasing the knowledge of postpartum mothers at RSIA Murni Teguh Rosiva Medan, obtained p-value = 0.000 <0.05. There was a difference in the knowledge of postpartum mothers before and after being given education on newborn umbilical cord care (pretest-posttest). The conclusion of the study was that mothers' knowledge of umbilical cord care increased after being given education. It is recommended for further researchers to conduct further research using other research variables such as attitudes, motivations, perceptions, and others, to complement the existing research results.

The Baayun Counseling Socialization Program at the Health Center is designed to improve the understanding and skills of health workers in implementing a more humane and local culture-based counseling approach. Baayun counseling is a therapeutic communication method that integrates cultural values in the interaction between health workers and patients, so that services become more personalized, empathetic, and meaningful. This program is carried out through several stages, namely needs analysis, socialization, and effectiveness evaluation. The main target is health workers in primary services who interact directly with patients. The expected results of this program include improving the competence of health workers in understanding and implementing Baayun Counseling, as well as increasing patient satisfaction and compliance with health services. Program evaluations show that this approach is able to create positive changes in communication patterns, strengthen the relationship between health workers and patients, and improve the overall quality of counseling services. By adopting Baayun Counseling, Puskesmas can strengthen the cultural dimension in health services, making them more relevant and responsive to the needs of local communities. The program also has the potential to be replicated in other culturally rich regions as part of a community-based health service quality improvement strategy.

Hospitals, as healthcare institutions, bear the responsibility of delivering safe, high-quality, and patient-centered services. Hospital accreditation serves as a crucial mechanism to ensure service quality and legal protection for patients, particularly in medical dispute cases. This study aims to analyze the impact of accreditation on patient legal protection, both preventively and repressively. The research employs a normative legal method with statutory and conceptual approaches, utilizing primary, secondary, and tertiary legal materials. Data were analyzed through document studies covering Law Number 17 of 2023 on Health, government regulations, presidential regulations, and technical regulations from the Ministry of Health regarding accreditation standards and procedures. The findings indicate that accreditation functions as a continuous evaluation mechanism to ensure medical services comply with safety standards and clinical governance, strengthens patients’ rights to information, informed consent, and quality care, and reduces the risk of medical disputes. However, implementation challenges exist, including limited resources, compliance performed as formalities, and inconsistent supervision. Therefore, accreditation is not merely an administrative symbol but a strategic legal instrument that enhances patient safety culture and hospital accountability, ensuring that healthcare delivery meets professional, ethical, and legal standards.

Oxidative stress-induced apoptosis and chromatin instability are usually associated with male infertility and undermine the sperm DNA integrity. Recently, Vitamin K₂ (menaquinone) became a bioactive compound whose regulation action can be found in both apoptosis and transcriptional signaling. This study examines how Vitamin K₂ can be protective in the regulation of apoptotic pathways and stability in sperm chromatin by an integrative experimental and in silico analysis. Vitamin K₂ levels, DNA fragmentation level of infertile men's serum and semen samples (Aniline Blue), and the expression levels of apoptosis-associated genes (BAX, BCL-2, and CASP-3) in the samples were examined by qRT-PCR. The characterization of Vitamin K₂ binding affinity to apoptotic proteins was done using dynamics simulations. Findings showed that high levels of Vitamin K₂ had a significant positive correlation with reduced levels of DNA fragmentation and good control of apoptotic genes with reduced BAX and CASP-3 and increased expression of BCL-2. In general, the results indicate Vitamin K₂ as a potential regulator of sperm death and chromatin integrity that provides new therapeutic understanding on how male infertile patients can be treated.

Cytokines and Vitamin K in crohn’s disease patients have been evaluated to discover the conceivable via biomarkers of diagnosed patients compared to control. Sera samples of Eighty patients and control of both genders. forty patients diagnosed crohn’s which the span of age between (20-36) years and 40 healthy volunteers as a control with span age (18-39) years. The patient were guests to Marjan hospital in Babylon city during the period (1/July/2025 to 1/September/2025). The current results showed a significant difference in statistic marks at (P<0.05). Vitamin K in patients below control. There is significance different between values of patients and controls in Magnesium, Calcium, Vitamin K, InterL10 and Toll-like receptor 4. According to word axel, there is magnitude significant relationship among cytokine InterL10 and Toll-like receptor 4, Magnesium, Calcium, & Vitamin K. The cytokines both InterL10 and Toll-like receptor 4 patients’ levels larger than control levels. Calcium and Magnesium which there is significance variance between both patients and Control

Femoral fractures resulting from road traffic accidents (RTAs) are a major cause of morbidity in developing countries, particularly among economically active young adults. Despite the increasing rate of RTAs in Nigeria, there is a lack of localized data concerning the radiographic distribution and epidemiological characteristics of femoral fractures. This study provides region-specific baseline data for clinical decision-making and public health interventions. A retrospective descriptive study was conducted using patient case notes and radiographic records of 141 individuals with femoral fractures resulting from RTAs, presented at Erichris Diagnostic Centre, Benin City, between January 2019 and December 2022. Radiographs were evaluated to determine fracture location (proximal, middle, or distal third). Data were analyzed using SPSS version 20, and results were presented using descriptive and inferential statistics. Associations between fracture type, age, and gender were examined using Chi-square tests with significance set at p < 0.05. The majority of patients were males (87.2%) and within the 16–30-year age group (72.3%), with a mean age of 31.6 years. The right femur was affected in 55.3% of cases. Middle third femoral shaft fractures were the most prevalent (63.8%), followed by proximal (26.3%) and distal fractures (9.9%). There was no statistically significant association between gender and fracture type (p > 0.05) or between age group and fracture type (p > 0.05). This study demonstrates a high incidence of middle shaft femoral fractures among young adult males due to RTAs in Benin City. These findings highlight the urgent need for targeted road safety policies, improved trauma care infrastructure, and preventive strategies directed at high-risk groups. The data provided serve as a critical reference for orthopedic management and public health planning.