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Non-compliance with taking medication in diabetes mellitus sufferers will cause blood sugar levels to decrease or increase beyond normal limits  and as a result will cause complications or death. There is a need for health education regarding knowledge of diabetes patient medication adherence to prevent this. This research was conducted using a quasi-experimental research method (one-group pre-post test design). The sample in this study was 29 respondents taken using purposive sampling instruments using SAP, lealeats and questionnaires. the collected data was processed using the SPSS 24 version of the computer program to be analyzed using the Mc.Nemar nonparametic test with a significance level (α) of 0.05. The results of the bivariate analysis show that there is an influence of health education on knowledge of the level of dringking compliance in patients with type diabetes mellitus. The value obtained is p = 0,000 which means that Ha is accepted and Ho is rejected. The conclusions in the research show that there is an influence of knowledge education on treatment compliance.

Storage is an activity of storing and maintaining by placing the received pharmaceutical supplies in a place that is considered safe from theft and physical disturbance that can damage the quality of the drug. The purpose of this study was to determine the drug storage system at the Dearh Lanto Dg Pasewang General Hospital Pharmacy Warehouse which includes spatial arrangements, storage methods, stock card recording and drug quality observation. This is done by direct observation The research conducted is descriptive in nature, the data collection method in this study is by direct observation. The data management and analysis techniques that the authors used in this study included reducing the checklists that had been obtained. Based on the results of research conducted at the Pharmacy Warehouse of the Lanto Dg Pasewang Hospital, in general, the drug storage system was 93.22% in the good category. The assessment includes the physical condition of the warehouse with a value of 90.47% in the good category. How to store drugs with a value of 93.33%. Stock card recording with a percentage value of 100% is in the good category. Drug quality monitoring with a percentage value of 100% is in the good category, so that the medicines stored in the Warehouse of the Regional General Hospital Lanto Dg Pasewang Jeneponto are in good condition and the quality of the drugs is maintained.

Hypertension is a disorder in the blood vessels that causes blood pressure to increase, causing the heart to pump harder to circulate blood to organs and tissues throughout the body. The incidence of hypertension in Indonesia continues to increase because the majority of people do not take medication and do not regularly take medication because they feel healthy. Therefore, people with hypertension must receive treatment to reduce mortality and morbidity associated with hypertension. This requires knowledge regarding the use of hypertension medication by providing education using audio-visual media

The impact of drug use is extremely harmful in the long run. In this regard, this article aims to reflect more deeply on the real impacts of drug use in our society. Through a better understanding of this issue, it is hoped that a stronger collective consciousness can be formed to face this challenge in a more effective and holistic way. The method used in this research is qualitative. The result is that drug use is not only an individual problem, but also a complex social problem that requires a holistic approach from various parties, including the government, health institutions, education, and society as a whole. Prevention, education, and access to adequate rehabilitation and health care services are key to addressing the negative impacts of drug use.

Cipacing Village, Jatinangor District, Sumedang Regency is an area that has extensive plantation land and rice fields. This village is still beautiful with lush green trees and vast fields which are its own attraction. Many people in Cipacing Village still use plant species to treat diseases. The aim of this research is to identify the use and utilization of medicinal plants in Cipacing Village. This type of research is descriptive with qualitative research methods. Sampling was carried out using purposive sampling technique. Data collection was obtained from the results of semi-structured interviews. There were 30 respondents in this study who were described by characteristics such as gender, age and level of education. Based on research conducted, the plants used as medicine by the community are 23 families, 28 genera and 29 species with the dominant family being Zingiberaceae (26%) and the co-dominant family being Piperaceae (8.7%). The highest habitus was found in herbaceous plants (40%) while the part of the plant that was widely used was the leaves (57%). The most dominant plant processing used is by boiling the leaves and then filtering the boiled water for drinking.

Commercial activities contribute to increasing sales of agricultural products. One of the agricultural products is Tanaman Obat Keluarga (TOGa). TOGa plants are an additional source of income. However, the difficulty of selling is that often the price is not as good as the market. Through assistance in the use of social media and digital financial records, it is expected to contribute to increasing the income of residents of Purwoseco Hamlet and Karangrejo Hamlet. The results of service activities show that > 50% of residents experience an increase in understanding and knowledge of the knowledge provided. The satisfaction level of service participants showed an average score of 65%, which is very good. This shows that the service participants are satisfied with the course of service activities.

Drug-resistant tuberculosis (TB) is an escalating global health issue, particularly with the rise of multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB), which complicate treatment and control efforts. Resistance to both first-line and second-line drugs weakens the effectiveness of standard WHO-recommended therapies, while alternative drugs can cause severe side effects and reduce patient adherence. This study aims to explore the integration of bioinformatics and pharmacogenomics in supporting personalized TB treatment to improve therapeutic success and reduce the risk of further resistance. The research employed a laboratory-based experimental design with a bioinformatics approach, involving TB patients with clinical evidence of drug resistance. Clinical samples were analyzed through whole genome sequencing to identify gene mutations associated with resistance, followed by pharmacogenomic mapping to predict pharmacological responses based on patients’ genetic variations. The results revealed several specific gene mutations consistently linked to resistance and produced individualized therapeutic recommendations that were more targeted than standard protocols. Effectiveness evaluation demonstrated that genome-based personalized therapy yielded higher treatment success rates, faster recovery times, and lower rates of subsequent resistance. These findings highlight the significant potential of precision medicine in TB management, particularly for resistant cases that are difficult to treat with conventional approaches. In conclusion, the integration of bioinformatics and pharmacogenomics plays an essential role in strengthening TB treatment strategies through a personalized, adaptive, effective, and sustainable approach. Nevertheless, its implementation still faces challenges such as high costs, limited infrastructure, and the need for clear regulations regarding the use of patients’ genomic data.

Medicinal plants are plants with positive pharmacological effects on the human body and are usually grown on a home or communal scale. These medicinal plants can then be used as traditional medicine which can be made easily. The plants chosen are usually plants that can be used to treat simple health problems such as flu and coughs. Medicinal plants can increase the body's immunity because they can prevent disease through the secondary metabolites they contain. In this service activity, two activities were carried out separately, namely socialization and planting medicinal plants with residents. The outreach was carried out to provide information to the residents of Medan Helvetia District regarding medicinal plants so that these medicinal plants can be useful after being planted. Planting is also carried out to increase awareness regarding land use, as well as being a starting point for residents in cultivating medicinal plants. This socialization on the use of family medicinal plants aims to provide information to the people of Kexamatan Medan Helvetia in using medicinal plants. It is hoped that this community service activity will help increase public knowledge about the importance of planting and utilizing medicinal plants to create a healthy society.

DHF cases in Indonesia in 2014 showed that there were 10 provinces in Indonesia that had the highest dengue cases and one of them was South Sulawesi Province (7). Based on data from the South Sulawesi Provincial Health Service, there were 2,166 people suffering from dengue fever from January to May 2020. 19 of them died. And the most in Gowa Regency were 6 people. Borisallo Village, Parangloe District, is one of the villages supported by the Indonesian Muslim University. We chose this location as a service partner area because dengue cases in Gowa Regency, based on the 2019 South Sulawesi Provincial Health Service Profile, were the 2nd highest area with dengue cases after Pangkep Regency, namely 474 sufferers. Then in 2020 Gowa Regency was the area with the most dengue cases, namely 457 people. The aim of this service is to improve cadres' skills in making their own mosquito repellent from natural ingredients that are safe and environmentally friendly, increase cadres' knowledge about the dangers of chemical mosquito repellent, increase cadres' knowledge in making preventive efforts against diseases transmitted by mosquito vectors. The solutions offered include training in making electric liquid mosquito repellent from sweet orange peel, providing education regarding the dangers of chemical mosquito repellent for health, providing education on preventive efforts to prevent diseases transmitted by mosquito vectors.  

Indonesia's Health Profile in 2022, there were 845,000 cases of pulmonary TB and in 2021 there were 420,994 cases. There were 563,879 new confirmed cases of pulmonary TB and relapses. If this is not adhered to, it will cause drug resistance. The aim of the research was to determine the factors that influence the compliance of pulmonary TB sufferers in taking medication at the Batang Beruh Health Center UPT, Sidikalang District, Dairi Regency. The research design uses an analytical survey research method with a cross sectional research design. The population in this study was all 126 pulmonary TB patients. The sample was 56 people with a purposive sampling method. Data analysis uses univariate, bivariate and multivariate analysis. The results of the study showed that there was an influence of knowledge p = 0.010, attitude p = 0.006, family support p = 0.000 and drug side effects p = 0.000, while the variable that had no influence was gender, p = 0.057, on the compliance of pulmonary TB sufferers in taking medication. at UPT Batang Beruh Community Health Center, Sidikalang District, Dairi Regency, while the dominant factor was family support, p = 0.006 < 0.025, 95% CI = 2.715-519.110 and OR = 37.543. The conclusion is that there is an influence of knowledge, attitude, family support and side effects of drugs, while the variable that has no influence is gender on the compliance of pulmonary TB sufferers in taking drugs at UPT Puskesmas Batang Beruh, Sidikalang District, Dairi Regency. Recommended to UPT. Batang Beruh Community Health Center, Sidikalang District, increases public knowledge about pulmonary TB among sufferers and visiting residents by providing outreach and providing information on the SITB application. Targets at risk of contracting pulmonary TB are the sufferer's family and health workers. And as a Medicine Taking Supervisor are the families of pulmonary TB sufferers.

Pengelolaan obat sangat penting dalam sistem pelayanan kesehatan, sehingga penerapannya harus dilakukan secara tepat dan bijak. Berbagai permasalahan terkait obat dapat dikarenakan masyarakat kurang paham tentang penggunaan dan penanganan obat dengan benar. Masalah penyalahgunaan obat-obatan di masyarakat merupakan faktor yang perlu menjadi perhatian terutama daerah pedesaan dengan fasilitas kesehatan terbatas. Tujuan kegiatan ini yaitu untuk memberikan edukasi dan informasi tentang cara mendapatkan obat, menggunakan obat, penyimpanan obat hingga pada proses membuang obat dengan baik dan benar. Metode penyuluhan ini dilakukan secara langsung dengan ceramah dan diskusi secara interaktif. Diskusi dilakukan dengan metode tanya jawab terkait materi serta konseling berdasarkan masalah setiap individu terkait penggunaan obat. Materi selain disajikan secara presentasi juga diberikan melalui leaflet terkait cara pengelolaan obat yang baik dan benar (DAGUSIBU). Kegiatan penyuluhan ini telah dicapai dengan menambah wawasan dan informasi kepada masyarakat tentang cara pengelolaan obat yaitu DAGUSIBU dalam kehidupan sehari-hari.

Children's syrup medicine risks containing Ethylene Glycol (EG) and Diethylene Glycol (DEG) contaminants, which are the solvents for syrup medicine. The syrup contains the risk of acute kidney failure. It may be poisoned because it has diethylene glycol. This condition may influence the parents' perception as the person who allowed the children to consume that medicine, which may affect their health. This research aimed to analyze the students' perception toward the use of syrup medication with the incidence of acute kidney failure among children in Gampong Jawa of Banda Aceh. This quantitative research used a correlative descriptive method using a cross-sectional design. The sample in this research was 86 parents who have children aged 0-6 years old which was chosen using total sampling. This research was conducted from July 8th to 13th, 2023. The result of the statistic test using the chi-square test obtained that the p-value was 0.042. It was concluded that Ho was rejected and Ha was accepted, which means there was a correlation between parents' perception and the use of syrup medication.

Abstract.Hypertension is one of the main risk factors for heart problems. Apart from causing heart failure, hypertension can also result in kidney failure and cerebrovascular disease. This disease is often called the silent killer because there are no symptoms and without realizing it, sufferers experience complications in vital organs. This study aims to assess factors influencing adherence to taking anti-hypertensive medication in hypertensive patients at the Pekkae Community Health Center. This research presents the characteristics of respondents, Univariate data analysis of each variable to see the relationship between the Independent Variable and the Dependent Variable using the Chi-Square test. Based on the results of research conducted in the Pekkae Community Health Center working area, it was found that there was a relationship between predisposing factors including knowledge, beliefs, values ​​and attitudes towards compliance with taking antihypertensive medication for hypertension sufferers at the Pekkae Public Health Center, Barru Regency.

Dyspepsia includes a collection of clinical symptoms consisting of discomfort or persistent (episodic) or recurrence in the upper abdomen. Dyspepsia can be influenced by several factors, including increased gastric acid secretion, diet, and environmental factors, as well as psychological factors such as stress. This research aims to determine the use of dyspepsia medication at the Puskesmas Pamarayan. The type of research used in this research is descriptive observational with a purposive sampling method. The population in this study was 230 dyspepsia patients who visited the Puskesmas Pamarayan. The sample in this study was 31 respondents who had been determined using the Slovin formula with an error tolerance limit of 5%. Data were analyzed descriptively using rationality guidelines which include correct diagnosis, correct drug selection, correct dose, correct time interval, alertness to side effects, and correct information. The results of the study showed that the treatment of dyspepsia at the Puskesmas Pamarayan was rational.

Drug management is a cycle including selection, procurement, distribution and use which is supported by an appropriate organizational structure, finances and management information system. The aim of this research is to determine drug management in the Pharmacy Installation at RSUD dr. Soeratno Gemolong, Sragen Regency.This research uses prospective and retrospective methods. Where retrospective data is taken from 2022 data. Prospective data is taken through direct observation. The results of this research are: the percentage of available funds and the required funds is 80%, the percentage of procurement and actual use is 98%, invoice errors are 0.47%, there are no delayed payments by hospitals, compatibility between drugs and stock cards is 100% , drug availability level of 16 months, warehouse management system with FIFO, FEFO and LASA marking systems, average time used to serve compounded prescriptions is 11 minutes and non-mixed prescriptions is 7 minutes, conformity of drug items with the National Formulary is 93%, frequency of procurement of each drug item 4-6x a year, turn over ratio 3 times, percentage of expired and damaged drug value 5.05%, dead stock percentage 3%, number of drug items per prescription sheet 3.5 items, percentage of prescriptions with generic names 88%. These results indicate that drug management in the Pharmacy Installation at RSUD dr. Soeratno Gemolong, Sragen Regency is not yet good.

Tuberculosis (TB) is a disease that is ranked 10th with the highest number of deaths. Side effects caused by Anti-Tuberculosis Drugs (OAT) are often experienced by TB patients and result in physical disorders that reduce the quality of life of TB patients. This study aims to analyze the relationship between OAT side effects and the quality of life of TB patients at the Banyuglugur Community Health Center The research design in the study used a cross sectional approach. The population of this study was all TB patients in the Banyuglugur health center working area who underwent treatment for <6 months according to the inclusion criteria in January 2022 - May 2023, totaling 40 people using the Total Sampling sampling technique. Data were collected using a questionnaire on OAT side effects and quality of life. The analytical test used was the Spearman Rank test. The results of this study showed that the side effects of OAT in 27 TB patients (67.5%) were severe and the quality of life of 31 TB patients (77.5%) was poor. The results of the analysis show a p value of .001 (smaller than 0.05), so there is a significant linear relationship between the OAT side effect variable and the quality of life of TB patients at the Banyuglugur Community Health Center. This research shows that the side effects experienced by TB sufferers, both mild and severe, greatly affect the quality of life of TB patients. Health workers must always carry out routine monitoring of OAT side effects experienced by TB sufferers and treat them as soon as possible so that they do not affect the quality of life of TB patients in terms of physical, nutritional or psychological aspects in order to prevent them from dropping out of treatment.

SDN Sitanggal 04 is one of the schools in Si Date Village, which is located very strategically because it is directly opposite the provincial road which is used by many public transportations. The school is also not too far from a large and busy traditional market and close to places for shopping and family recreation, so the health condition of the school's environment is very vulnerable. Therefore, the attitude of caring for the environment must be applied from an early age. One of them is through the cultivation of family medicinal plants (TOGA) in the school environment. The purpose of this service is to foster an attitude of caring for the environment in students, create a healthy school environment, provide insight and skills to students about family medicinal plants (TOGA) and how to grow them. The method used is Participatory Action Research (PAR). The results of this service show that the attitude of caring for the environment, the insights and skills of students at SDN Sitanggal  04 are increasing regarding family medicinal plants (TOGA) and their planting.

Drug storage is one of the security activities for drugs that have been received. Storage of drugs in pharmacy installations is part of the integrity or feasibility of drugs before they are given to patients. Because errors in drug storage can make the dose or potency of the drug decrease and cause losses to the hospital. This research includes non-experimental research in the form of quantitative descriptive research conducted by observation and interviews related to the process of storing pharmaceutical preparations through an evaluation based on the Minister of Health of the Republic of Indonesia No. 72 of 2016, and the Director General of Binfar in 2010 and analysis of drug storage indicators. The average result of conformity to the Permenkes is 86%, the average is obtained from 70% storage requirements, 100% storage components, 100% storage systems, 80% storage methods and 80% storage equipment. The average result of conformity at the Director General of Binfar is 93%, the average is obtained from the spatial arrangement of 100%, preparation of 100% drug stock and 80% storage facilities. And the average results of storage indicators are 40%, with a TOR value of 5,1 times a year, warehouse arrangement is based on FIFO/FEFO, the percentage of expired/damaged drugs is 0.25%, and the percentage of empty drugs is 92%, the percentage of drugs dead by 0.04%. Based on the evaluation of the suitability of drug storage in the Pharmacy Warehouse of RSUD dr. Soekardjo, City of Tasikmalaya, it is necessary to increase the suitability of drug storage.

Pemberdayaan kepada masyarakat ini merupakan sarana untuk mendekatkan tanaman obat kepada upaya-upaya kesehatan masyarakat yang meliputi preventif, promotif dan kuratif, selain itu untuk membentuk individu yang berjiwa sosial dibidang kesehatan, mengetahui tingkat kesehatan masyarakat dan meningkatkan pengetahuan masyarakat.Tanaman Obat Keluarga adalah tanaman hasil budidaya rumahan yang berkhasiat sebagai obat. Metode yang yang digunakan dalam pengabdian ini adalah : sosialisasi dan pelatihan pegolahan tanaman obat. Tujuannya adalah agar masyarakat mampu mengolah tanaman obat secara mandiri untuk pencegahan penyakit.

Sertifikasi halal merupakan hal penting dalam sebuah industri bukan hanya sebagai penjamin kehalalan bagi konsumen namun sertifikasi terhadap kehalalan produk sudah tercantum pada Undang-undang Nomor 33 Tahun 2014 Tentang Jaminan Produk Halal menegaskan bahwa produk makanan, obat-obatan, kosmetik dan produk lainnya wajib bersertifikasi halal, yang tidak hanya berlaku bagi perusahaan besar tapi juga pada UMKM. Penelitian ini bertujuan untuk menetapkan titik kritis pada produk Pempek Hafis untuk pengendalian resiko halalnya suatu produk. Penelitian ini dilakukan dengan tiga tahap, tahan pertama menentukan lokasi penelitian, tahap kedua melakukan observasi dan identifikasi pada rumah produksi Pempek Hafish dan tahap ketiga mengolah data dan informasi yang sudah didapat. Produk yang diidentifikasi yakni pempek dan tekwan. Hasil studi menunjukan bahwa titik kritis terdapat pada proses pengemasan kuah atau cuka pempek dan proses pembentukan adonan pempek yang tidak menggunakan sarung tanang, tempat pengolaha adonan berdekatan dengan tempat pencucian piring dan terdapat beberapa sampah yang tidak segera dibersihkan.