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Uric acid (UA) is a waste product formed when the body breaks down purines, which are natural compounds found in the body and can be found in various types of foods such as alcohol, shellfish, and liver. Hyperuricemia is caused by increased uric acid production, decreased excretion, or a combination of both processes. Most people with hyperuricemia are asymptomatic (85% to 90%), but increased levels of uric acid in the blood or urine can cause gout or nephrolithiasis. Hyperuricemia and hyperuricosuria are also associated with other disorders such as metabolic syndrome, diabetes mellitus, cardiovascular disease, hypertension, atherosclerosis, obesity, and chronic kidney disease. The Community Service (PKM) activity held in Grogol Village, West Jakarta, aims to increase awareness of the elderly community regarding the importance of early detection of hyperuricemia. This program uses the Plan-Do-Check-Act (PDCA) approach, starting from planning uric acid level examinations and compiling educational materials, followed by implementing interactive screening and counseling, evaluating results, and following up in the form of medical referrals for participants with abnormal results. Of the 71 participants involved, only 1 person had uric acid levels above normal. Through education on low-purine diets, the importance of hydration, and physical exercise, this activity is expected to be able to reduce the incidence of hyperuricemia and its complications, as well as support the realization of a healthier elderly community that is aware of its metabolic health.

Malaria remains a significant public health issue both globally and in Indonesia, particularly affecting high-risk groups such as infants, young children, and pregnant women. The increasing incidence of malaria is closely linked to environmental and behavioral factors. This study aims to examine the relationship between community behavior and environmental conditions with malaria incidence at the Arso City Health Center, Keerom Regency. A quantitative, cross-sectional design was used, allowing analysis of variables at a single point in time. The sample was selected through simple random sampling based on inclusion and exclusion criteria. Findings revealed that there is no significant relationship between the habit of going outside the house and malaria incidence (p = 0.07). However, there is a significant relationship between the use of mosquito repellent and malaria incidence (p = 0.000). Similarly, using mosquito nets and gauze also showed a significant relationship with reduced malaria cases. Environmental aspects such as mosquito breeding sites and unsealed house walls were also found to be significantly associated with malaria occurrence. These results suggest that both behavioral factors—particularly protective measures—and environmental conditions contribute to malaria transmission in the community. Public health efforts should prioritize education on preventive behaviors and improvements in living environments to reduce malaria risk.

Preeclampsia is a condition of hypertension occurring after 20 weeks of gestation, accompanied by organ dysfunction and proteinuria. Preeclampsia is classified into Early Onset Preeclampsia (EOPE), which occurs before 34 weeks of gestation, and Late Onset Preeclampsia (LOPE), which occurs after 34 weeks of gestation. EOPE carries a higher risk of maternal and fetal complications compared to LOPE. This research aims to analyze the complications in mothers and fetuses with EOPE and LOPE that were terminated at RSUD Raden Mattaher Jambi between 2020 and 2022. This descriptive research was conducted in the Medical Records Department of RSUD Raden Mattaher, Jambi, involving 82 patients who experienced both maternal and fetal complications with EOPE and LOPE that were terminated. Sampling was carried out using the total sampling technique based on inclusion and exclusion criteria. The results of this research showed that the prevalence of EOPE was 69.5%, while LOPE accounted for 30.5%. Maternal complications were more commonly found in EOPE cases, including eclampsia (42.1%), HELLP syndrome (36%), premature rupture of membranes (14%), placental abruption (14%), and maternal mortality (5.3%). Fetal complications in EOPE included Respiratory Distress Syndrome (RDS) (10.5%), prematurity (26.3%), low birth weight (29.8%), Intrauterine Growth Restriction (IUGR) (10.5%), and Intrauterine Fetal Death (IUFD) (1.8%). The perinatal mortality rate in EOPE was 7%, with asphyxia recorded in 12.3% of cases. EOPE is more frequently encountered than LOPE and is associated with more severe maternal and fetal complications. Early detection and management of EOPE are crucial to reducing complications and improving pregnancy outcomes.

Premenstrual Syndrome (PMS) is a collection of physical and emotional symptoms occurring prior to menstruation that can disrupt daily activities. Dietary patterns and nutritional status are known to influence PMS symptoms. This study aims to analyze the relationship between dietary intake (energy, carbohydrates, protein, fat, magnesium, and vitamin B6) and nutritional status (based on Body Mass Index/BMI) with the incidence of PMS among female students from both health and non-health study programs at Universitas Airlangga. This research employed an analytical observational study with a cross-sectional design. A total of 103 female students from the 4th semester of the Nutrition and Islamic Economics study programs were selected through proportional random sampling. Data were collected using questionnaires on respondent characteristics, a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), anthropometric measurements, and the Shortened Premenstrual Assessment Form (SPAF). Data analysis was performed descriptively and inferentially using Spearman's rank correlation test. The results showed a significant relationship between energy intake (p = 0.002) and fat intake (p = 0.001) with PMS. No significant relationship was found for carbohydrate, protein, magnesium, and vitamin B6 intake (p > 0.05). Additionally, nutritional status based on BMI was significantly associated with PMS (p = 0.001), indicating that both underweight and overweight students were more likely to experience PMS. These findings highlight that imbalanced energy and fat intake, as well as abnormal nutritional status, may be contributing factors to PMS. Therefore, increasing awareness of proper nutrition and reproductive health is essential to reduce PMS symptoms among female students.

Chronic Energy Deficiency (CED) in pregnant women is a nutritional problem that has serious impacts on the health of both the mother and the fetus, such as increased risk of preterm birth, low birth weight, and labor complications. In Jambi City, CED cases have continued to rise year by year. This study aims to identify the determinants of CED among pregnant women in the working area of Putri Ayu Public Health Center, Jambi City. This study employed a quantitative approach with an analytical observational design using a cross-sectional method. The sample consisted of 82 pregnant women selected through purposive sampling. Data were collected using questionnaires and anthropometric measurements using MUAC. Data were analyzed using the Chi-Square test to examine the relationship between independent variables and the incidence of CED. The study found that the prevalence of Chronic Energy Deficiency (CED) among pregnant women was 28%. Statistical analysis revealed that infectious diseases (p=0.000), personal hygiene (p=0.009), environmental sanitation (p=0.037), education (p=0.004), occupation (p=0.000), and income (p=0.040) were significantly associated with CED in pregnant women. There is a significant relationship between infectious diseases, personal hygiene, environmental sanitation, education, occupation, and income with Chronic Energy Deficiency (CED) in pregnant women at Putri Ayu Public Health Center, Jambi City. It is expected that efforts to address chronic energy deficiency (CED) among pregnant women at Putri Ayu Public Health Center can be carried out through an integrated approach, including improvements in personal hygiene, environmental sanitation, prevention of infectious diseases, as well as enhancement of education, employment, and family income.

This study aims to analyze the toxic effects brought about by amphetamine use and its association with suicides. Suicide is an act of ending one's own life that is often associated with mental health disorders and life pressures. Amphetamines are classified as Class II psychotropic drugs that have a strong stimulant effect on the central nervous system, causing changes in behavior and mental activity, including hallucinations, thought disorders, and emotional changes. This study was conducted based on a literature review, identifying and analyzing various suicide cases involving amphetamine use through relevant literature. The results of the literature analysis indicate that amphetamine use significantly increases the risk of suicidal behavior, which can affect neurotransmitters, potentially triggering psychosis, nerve damage, and cardiovascular issues. Chronic use leads to dependence, cognitive impairment.

The SEBLAK program (Birth Certificate, Birth Registration, and Family Card) initiated by RS dr. Mohammad Zyn represents an innovation in digital-based civil registration services, aimed at improving efficiency, effectiveness, and transparency in public services related to population administration. This innovation integrates the processes of data collection, verification, and the issuance of administrative documents automatically through a digital system directly connected to the Department of Population and Civil Registration (Disdukcapil). Consequently, procedures for obtaining documents such as birth certificates and family cards can be carried out more quickly, easily, and without bureaucratic obstacles, while also providing more accurate and reliable data. The overall success of this program is supported by several key factors, including adequate technological infrastructure, continuous training for officers and the community, and effective socialization through various media and community forums. A qualitative approach was used to evaluate the implementation process and its impact on the community and hospital staff. Data were collected through in-depth interviews, observations, and documentation, then analyzed using the Miles and Huberman (1994) model. The results indicate that the implementation of this digital system can significantly reduce the time and costs associated with document processing, improve data accuracy, and strengthen public trust in government services. Beyond operational aspects, the SEBLAK program also positively impacts increasing access to administrative services for communities in remote and hard-to-reach areas. This aligns with the goal of expanding digital services inclusively and reinforcing the role of hospitals as the initial point and center for civil registration services while enhancing community participation in fulfilling their administrative rights. However, challenges remain, including technical infrastructure limitations, a lack of sufficient training for human resources, and the need to improve data security capacity. Therefore, continuous capacity building for human resources and infrastructure development are crucial to ensure the sustainability and success of this program, which can serve as a model for innovative public services that other institutions in Indonesia can adopt.    

The legal mechanism of bankruptcy relies on the concept of debt, because the absence of debt undermines the fundamental purpose of bankruptcy as a legal institution to liquidate the debtor's assets to satisfy creditors' claims. Debt is the main criterion that must be met in order to be able to apply for bankruptcy, along with additional provisions such as having two or more creditors, as stipulated in Article 2, paragraph (1) of Law Number 37 of 2004 concerning Bankruptcy and Suspension of Debt Payment Obligations (Bankruptcy Law). Notaries who have completed the bankruptcy process and are undergoing rehabilitation to improve their good name cannot re-apply to become Notaries. Here, the Notary will lose his/her right to work to carry out his/her position simply because the Notary has or has been sentenced to bankruptcy by the court. This bankruptcy is simply the notary's inability to pay the debt owed to the creditor, not a criminal act. If associated with the provisions contained in the 1945 Constitution of the Republic of Indonesia, namely Article 28 letter d concerning Human Rights which explains that everyone has the right to work and receive fair and proper compensation and treatment in employment relations, the efforts made in this problem are handled in accordance with the law and will be a substantial obligation for the curator. Based on Article 1 number 5 (Law Number 37 of 2004 concerning Bankruptcy and Suspension of Debt Payment Obligations), it states that a curator is an individual or an estate office appointed by the court to resolve and manage all problems of the bankrupt debtor's assets under the supervision of a supervising judge based on applicable laws. The citation of the law shows the clear jurisdiction of the curator over the debtor's property and assets.

Venous Thromboembolism (VTE) is a common complication in cancer patients. The treatment of VTE in cancer patients involves anticoagulant therapy using Vitamin K Antagonists (VKAs), including warfarin. VTE can be managed with warfarin administration, typically preceded by bridging therapy with heparin. The objective of this literature review is to examine and analyze studies related to the impact of warfarin use on cancer risk. The review was conducted on articles published in English over the past 10 years (2013–2024) using electronic databases such as Google Scholar and PubMed. The findings suggest that warfarin may be associated with improved overall survival in cancer patients and may have protective effects against certain types of cancer. Warfarin may exhibit antineoplastic properties through mechanisms both dependent on and independent of coagulation pathways, the latter mediated by the inhibition of the GAS6-AXL signaling pathway.  

Household waste management is an important part of maintaining environmental quality. This article is a literature review that aims to identify and analyze the relationship between household waste management and its impact on environmental quality. The purpose of this study is to gain a better understanding of the extent to which household waste management behaviors and systems can affect environmental conditions and public health. The method used is a systematic literature review of various scientific journals, research reports, and policy documents published in the last ten years. Data sources were taken from academic databases such as Google Scholar, ScienceDirect, and PubMed, with a focus on studies discussing aspects of waste management, sanitation, and health impacts in residential environments. The results of the study show that poor urban waste management, such as littering and open burning, is associated with an increase in environmental diseases. Conversely, good management systems, such as regular sorting and transportation, have a positive impact on the cleanliness and health of the residential environment. Conclusion Good household waste management plays an important role in maintaining a healthy living environment. Organized and participatory practices can reduce the risk of disease and create a clean, healthy, and sustainable environment for communities. 

This research aims to explore how students’ interest plays a role in their ability to memorize the Qur’an in the Tahfizul Qur’an program at MTs Negeri 1 Banjarnegara. The study utilizes a descriptive qualitative approach, gathering information through observation, in-depth interviews, and documentation. Participants in this research include tahfiz students, tahfiz teachers, and the program coordinator. The data were processed and analyzed following Miles and Huberman’s framework, which involves phases of reducing data, displaying it, and drawing conclusions. The findings indicate that student interest positively and significantly affects their Qur’anic memorization achievements, both in terms of amount and quality. Higher interest is associated with more effective memorization. Additionally, this interest is influenced by internal factors, such as motivation and satisfaction, as well as external factors, including family and teacher support, all of which help foster a successful tahfiz learning process. The study underscores the necessity of developing and maintaining student interest to maximize the outcomes of the tahfiz program.

A comprehensive analysis of the impact of obesity on school-age children as well as the effectiveness of nutrition education interventions in an effort to mitigate its prevalence. Child obesity, which is based on Body Mass Index (BMI) above 2 standard deviation (SD), has broad implications for physical, social, emotional, and self-esteem health. This condition is also associated with decreased academic performance, reduced quality of life, limb growth disorders, sleep disfunction, sleep apnoea, respiratory complications, as well as accelerated bone maturation and sexual maturity.The findings show that school-based nutrition education is an effective strategy in increasing knowledge and delivery of nutrition interventions, especially when supported by all elements of the school. The duration and frequency of exposure to interventions are crucial factors for the success of nutrition education in triggering behavioural changes. Therefore, the prevention and management of obesity in children through structured nutrition education is essential.

Complete basic immunization, including DPT-HB 1,2,3, plays a vital role in reducing infant morbidity and mortality from vaccine-preventable diseases. However, immunization coverage remains suboptimal, partly influenced by maternal knowledge and attitudes. This study aims to determine the relationship between mothers’ knowledge and attitudes and the provision of DPT-HB 1,2,3 immunization at Mersip Public Health Center in 2023. This quantitative research used a descriptive analytic method with a cross-sectional approach. The study involved 134 respondents selected through purposive sampling. Bivariate analysis using the chi-square test showed a significant relationship between mothers' knowledge (p = 0.000) and attitudes (p = 0.008) with the administration of DPT-HB 1,2,3 immunization. The study concludes that better maternal knowledge and positive attitudes are associated with a higher likelihood of complete DPT-HB 1,2,3 immunization for their babies. These findings highlight the need for enhanced health promotion by healthcare providers targeting mothers in the Mersip area.

Overview: Low Birth Weight (LBW) is a significant health problem in Indonesia because it is at risk of increasing neonatal mortality and morbidity. Objective: This study aims to analyze the risk factors associated with the incidence of LBW in newborns at Prof. Dr. Margono Soekarjo Purwokerto Hospital. Research Method: The method used is an analytical observational study with a cross-sectional design. A sample of 200 mothers and babies was obtained through purposive sampling techniques. Data were collected from medical records and analyzed using the chi-square test and logistic regression. Research Results: showed that prematurity had a partial effect on LBW with a sig value of 0.000 <0.05, and showed that if the incidence of prematurity increased by one percent, assuming the value of other variables remained constant, it would increase the incidence of LBW by 2.769 percent. Variables parity, maternal age, anemia, twin pregnancy, hydramnios, PEB, Placenta Previa, KPD, prematurity, fetal pregnancy simultaneously affected LBW. Conclusion: parity, maternal age, anemia, twin pregnancy, hydramnios, PEB, Placenta Previa, KPD, prematurity, fetal pregnancy simultaneously affect LBW.

This study investigates the linguistic expression mendokusai as used by the character Nagi Seishirou in the anime Blue Lock: Episode Nagi, examining how this phrase reflects his personal attitude and patterns of social behavior. Mendokusai, commonly found in Japanese youth language, conveys meanings such as “bothersome,” “annoying,” or “too much trouble,” and is often associated with a passive or indifferent tone. Adopting a pragmatics and sociolinguistics framework, this research analyzes the function of the expression within the character’s dialogue and its role in shaping Nagi’s identity as a so-called “lazy genius.” Employing a descriptive qualitative method, the study closely examines selected scenes in which Nagi uses mendokusai across different social and emotional contexts. The findings suggest that Nagi’s repeated use of the phrase is not merely habitual but a deliberate linguistic strategy that highlights his aversion to social expectations, preference for simplicity, and effortless self-assurance. This research demonstrates how the recurrence of a single expression can serve as a significant marker of character identity and behavior, especially in contemporary portrayals of Japanese youth.

Frozen shoulder is a musculoskeletal disorder of the glenohumeral joint characterized by pain, stiffness, and decreased range of motion, generally occurring at the age of 45-60 years and often associated with low physical activity or comorbid diseases. This study aims to evaluate the effectiveness of physiotherapy interventions in the form of a combination of ultrasound, Transcutaneous Electrical Nerve Stimulation (TENS), muscle release, and exercise therapy in a 72-year-old male patient with left frozen shoulder. The method used is a case study with interventions including ultrasound, TENS, muscle release, and active, passive, isometric, pendulum, walking finger, and passive stretching exercises given during three meetings. The results showed a decrease in silent, pressure, and motion pain, as well as a decrease in the SPADI score indicating an increase in shoulder function. The implications of this study indicate that the combination of electrotherapy and exercise therapy modalities can provide positive results in reducing pain and increasing functional activity in cases of frozen shoulder, although further research is needed with more varied intervention designs and durations to strengthen these findings.

Malaria is an infectious disease caused by Plasmodium parasites and transmitted through the bites of female Anopheles mosquitoes. It remains a serious public health issue in various endemic regions, particularly in developing countries. This study aims to identify the factors associated with malaria incidence and evaluate the effectiveness of prevention and control programs that have been implemented. A quantitative approach with a descriptive correlational research design was used, involving secondary data from the Health Office reports and primary data collected through field surveys in the endemic area of PT. Tandan Sawita Papua, Keerom Regency. The results showed that malaria incidence is associated with the use of mosquito nets and the use of mosquito repellents. The study concludes that an integrated approach to malaria control is essential, including community education, environmental improvements, and sustainable health policy support.

COPD is a condition characterized by airflow obstruction that cannot be completely corrected. This limitation generally worsens over time and is associated with abnormal permeability to noxious particles or gases, resulting in narrowing of the airways, increased mucus secretion, and changes in the vascular system. The increase in chest expansion capacity is caused by the activity of respiratory muscle contraction. The activity of the respiratory muscles plays a role in chest expansion, which also affects lung growth. It is stated that the strength of the respiratory muscles decreases with age. Loss of intercostal muscle mass and strength are factors that reduce the ability of chest wall presence or development. This study used a case report design research method. Physiotherapy management for COPD is increasingly focused on exercise-based rehabilitation, both in outpatient and inpatient settings. Some therapies such as breathing exercises, thoracic expansion exercises and muscle release.

Introduction: Chronic Obstructive Pulmonary Disease or often referred to as COPD, is a disease that occurs due to limited airflow, this is caused by abnormalities of the airways and/or damage to the alveoli, abnormalities or damage that occurs are caused by significant exposure to hazardous particles or gases, not only due to exposure, COPD is also influenced by lung abnormalities. Dyspnea is a condition that describes a sensation of shortness of breath, which is characterized by obstruction of airflow, or difficulty breathing and chest tightness which is often associated with heart or respiratory disease. Purpose: This study is to determine the management of physiotherapy in cases of right chronic obstructive pulmonary disease. Method: This study uses a case report approach in patients with right chronic obstructive pulmonary disease by providing interventions in the form of nebulizers, pulsed lip breathing and muscle release for 4 weeks 5x meetings with doses of 3 times a day every week. Evaluation is carried out using the vital sign index, auscultation, borg scale, MMRC scale and thorax cage mobilization examination. Results: evaluation measurements using vital sign index, auscultation, borg scale, MMRC scale and thorax cage examination. Thus, the results show an increase and decrease in the degree of shortness of breath before and after intervention. Conclusion: there is an increase and decrease in shortness of breath before and after intervention.

Early marriage in Indonesia is a significant reproductive health issue, particularly for adolescent girls. This study aims to explore the impact of early marriage on reproductive health and the contributing factors. Early marriage, defined as marriage before the age of 19, can lead to various health problems, including a high risk of pregnancy complications and mental health issues. Data indicates that Indonesia has a high rate of early marriage, with the highest prevalence in several provinces. The method used is a literature review analyzing 30 relevant scientific journals from 2015 to 2025. The findings indicate that early marriage is associated with an increased risk of pregnancy complications, disturbed mental health, and low knowledge about reproductive health among adolescent girls. Further efforts are needed in reproductive health education and policies to prevent early marriage.