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Emergency conditions refer to situations that require immediate intervention because they have the potential to threaten life, impair organ function, or cause disability if not managed promptly and appropriately. Status epilepticus is a neurological emergency defined by seizures lasting five minutes or longer, or by repeated seizures without regaining consciousness between episodes. Status epilepticus can develop in individuals both with and without a previous diagnosis of epilepsy and may result from a wide range of causes, such as metabolic abnormalities, infections of the central nervous system, stroke, head injury, sudden discontinuation of antiepileptic medications, and alcohol intoxication or withdrawal. Clinically, this condition is classified into convulsive and non-convulsive status epilepticus. The diagnosis is primarily clinical and must be established rapidly, while electroencephalography plays an important role, particularly in cases of non-convulsive status epilepticus. Management emphasizes initial stabilization of the airway, breathing, and circulation, after which benzodiazepines are given as first-line treatment, including intramuscular midazolam, intravenous lorazepam, or intravenous diazepam. Status epilepticus represents the most severe form of seizure activity, characterized by continuous, unremitting seizures accompanied by strong muscle contractions, respiratory compromise, and widespread abnormal electrical activity in the brain. If not treated promptly, the risk of permanent brain tissue damage increases and the condition may ultimately lead to death.

Background: Dental caries is a major problem in orodental health, especially in children. The primary cause of caries is the activity of cariogenic microorganisms. Unbalanced remineralization of dental tissue followed by destruction of organic matters may cause cumulative and progressive damage to the tooth structure. Extensive caries lesions that have reached the pulp are an indication for pulp therapy with appropriate crown restoration. Case Report: A 10-year-old boy came with a complaint of a painful cavity in his upper right front tooth. The patient was considered communicative and cooperative. The patient also had a habit of consuming sweets. An intraoral examination revealed extensive caries on the entire surface of 53. A periapical radiograph showed a radiolucent area reaching the pulp cavity on the occlusal surface of 53 with resorption of the apical one-third of the root. Based on the examination results, reversible pulpitis was established as the primary diagnosis. The treatment plan was pulpotomy with a dental crown restoration. Treatment was carried out over four visits. First visit included complete examination, periapical radiography, and pulpotomy. The second visit included core buildup, tooth preparation, and dental impressions. The third visit included try-in and crown insertion, followed by a final follow-up visit. Conclusion: Pulpotomy with dental crown restoration can be an effective clinical approach to restore the function and aesthetics of anterior deciduous teeth, especially in cases that consider aesthetics and cost limitations.

Hospitals often face difficulties in determining patient treatment priorities due to limited medical resources and the uncertainty of patient conditions. Conventional prioritization methods tend to rely on subjective judgment, which can lead to inconsistent decisions and delays in treatment. This study aims to apply fuzzy logic in a decision support system to determine patient priority levels more objectively and systematically. The proposed method utilizes a fuzzy inference system that processes several criteria, including the severity of symptoms, vital signs, patient age, and waiting time. These criteria are represented as fuzzy sets and evaluated using a set of inference rules to generate priority classifications. The results indicate that the fuzzy logic–based system is able to classify patient priorities more consistently and transparently compared to manual assessment. The system provides clear priority categories that can support medical staff in making faster and more accurate decisions. The findings imply that the implementation of fuzzy logic in hospital decision support systems can improve the quality of healthcare services, enhance fairness in patient handling, and optimize the allocation of medical resources, particularly in emergency and high-demand situations.

Injuries, supported by continuous education, plays an essential role in preventing further injury and Sports injuries are common occurrences in physical activities, with minor injuries being the most frequently experienced by athletes, students, and the general community. Improper initial management of minor sports injuries may lead to more severe conditions and prolonged recovery periods. This study aimed to describe the management of minor sports injuries at Boawae Public Health Center based on observation and interviews with healthcare professionals. A descriptive qualitative method was employed through direct observation and structured interviews with a general practitioner and a nurse at Boawae Public Health Center. The results indicated that the most common minor sports injuries treated were contusions, mild sprains, muscle cramps, and muscle soreness. The initial management applied by healthcare providers was based on the RICE principle (Rest, Ice, Compression, and Elevation), accompanied by injury assessment before and after treatment. In addition, patients were provided with education regarding proper injury management and injury prevention. It can be concluded that appropriate early management of minor sports ensuring safe and sustainable participation in sports activities.

The growing number of alleged medical malpractice cases in Indonesia, particularly physicians’ misdiagnosis resulting in patient death, underscores the need for stronger legal certainty and accountability in healthcare services. Physicians are professionally obligated to conduct diagnosis and medical treatment in accordance with professional standards, service standards, and standard operating procedures; however, negligence may occur and lead to severe harm. This study aims to analyze the legal provisions governing physicians’ liability for misdiagnosis causing patient death and to examine the forms of legal responsibility that may be imposed. The research applies a normative juridical method using a case approach and literature review, relying on primary legal materials such as the Indonesian Civil Code, the Criminal Code, the Medical Practice Law, the Hospital Law, and Law Number 17 of 2023 on Health, supported by secondary and tertiary sources. The findings indicate that physicians may be held liable under civil, criminal, and administrative law if the essential elements of medical negligence are proven, namely duty of care, breach of duty, harm (including death), and a causal relationship between the misdiagnosis and the fatal outcome. Moreover, liability may extend to hospitals under the doctrines of vicarious liability, hospital liability, and strict liability. This study implies the importance of strengthening professional competence, reinforcing disciplinary mechanisms, and ensuring balanced legal protection for both patients and healthcare professionals within Indonesia’s health law framework.

This study aims to examine the effect of creative dance activities on the self-confidence of children aged 4–5 years at TK Pertiwi, Buluh Kasab Village. The background of this study is the low level of children’s self-confidence, which is reflected in passive behavior, reluctance to perform in front of the class, and a lack of courage to express themselves in front of others. This research employed a quantitative approach with a pre-experimental one-group pretest–posttest design. Data were collected through structured observation, while data analysis was conducted by calculating pretest and posttest scores, which were then analyzed using a paired sample t-test and effect size calculation to determine the strength of the treatment effect. The creative dance activities were implemented over six sessions by integrating elements of music, movement, and expression using two children’s songs, namely “Percaya Diri” by Abita and “Aku Bisa” by AFI Junior. The results indicated a significant improvement in children’s self-confidence, as shown by an increase in the mean score from 15.08 in the pretest to 32.75 in the posttest. The t-test results revealed a t-value of −31.006 with a significance level of 0.000 (p < 0.05). An effect size value of 6.43 indicated a very strong effect. Therefore, creative dance activities have a significant impact on enhancing early childhood self-confidence and are recommended as an effective learning strategy.

Type 2 diabetes is a persistent medical condition with an increasing incidence that requires long-term treatment. One of the decisive factors in blood glucose control Patient self-awareness is a key variable examined in this study. The research was conducted to assess the relationship between self-awareness and blood glucose levels among individuals with type 2 diabetes in the Tuban Community Health Center area. A correlational analytic study with a cross-sectional design was utilized. The study involved a population of 135 patients, with a sample of 101 respondents selected using simple random sampling.Research data collection was conducted using a self-awareness questionnaire and a blood glucose observation sheet. Data analysis was performed using a chi-square test with a significance level of 0.05. The results of the analysis showed a p-value of 0.002 (p < 0.05), indicating a significant association between self-awareness and blood glucose levels. Based on these results, the study findings generally indicate that greater self-awareness typically allows for more optimal control of blood glucose levels.  

Antibiotics are one of the main pillars in the treatment of bacterial infections and have contributed significantly to increasing human life expectancy. However, long-term use of antibiotics has serious consequences for the balance of the body's microbiome, especially the gut microbiome which plays an important role in maintaining homeostasis through the regulation of the immune system, metabolism, and protection against pathogens. This literature review aims to comprehensively analyze the impact of long-term antibiotic use on the structure, diversity, and function of the human microbiome. The scientific articles reviewed were obtained from PubMed, Scopus, ScienceDirect, and Google Scholar databases, including empirical research, systematic review, and meta-analysis published in the last ten years. The results showed that prolonged exposure to antibiotics consistently decreased microbiota diversity, altered the composition of bacterial communities, and triggered dysbiosis, which is often persistent even when therapy is stopped. Dysbiosis is associated with impaired immune system function, increased systemic inflammation, risk of allergic and metabolic diseases, and potential disorders on the intestinal-brain axis. This impact is more pronounced in vulnerable groups such as neonates and children, especially when exposure occurs during a critical period of development. In conclusion, long-term antibiotic use has broad systemic implications, so a more rational, prudent, and sustainable use strategy is needed to maintain the health of the human microbiome.

Corn milk yogurt is a fermented product that has a low protein content. One of the efforts to increase the protein content of corn milk yogurt is by adding spirulina and soy protein isolate as a source of high protein. The objectives of this research are 1) to study the formulation of high protein corn milk yogurt with the addition of spirulina and soy protein isolate; 2) to study the characteristics of corn milk yogurt. Corn yogurt with the addition of spirulina (0.08, 0.12 and 0.16%) and soy protein isolate (4.5, 8.5 and 12.5%) were tested for physicochemical and sensory characteristics. Results revealed Corn yogurt addition with of 0.08-0.16% spirulina and 4.5 - 12.5% soy protein isolates have protein content of 1.94 - 7.04%, water content of 76.0-81.1%, fat content of 0.66 – 1.17%, 14.5-16.6% of carbohydrate content, viscosity of 328.3-1128.7 mPas, total solids 16.01-17.93oBrix, pH of 3.41-3.67, lactic acid bacteria of 51 x 107 CFU/ml – 76 x107 CFU/ml.  Corn yogurt has sensory characteristics including yogurt taste of 2.60-3.68, green color of 2.42-3.82, yellow color of 1.45-2.53, corn flavor 2.27-2.60, beany flavor 2.70-3.17, spirulina flavor 2.23-3.08, viscosity 2.62-3.82 and preference of 2.25-2.9. The best formulation for making corn yogurt is a combination treatment with 8.5% soy protein isolate concentration and 0.12% spirulina with a protein content of 5.41%. While yogurt is preferred, this formula still needs some fine tuning to eliminate the fishy scent caused by the spirulina

Diabetes mellitus is a chronic disease with a steadily increasing prevalence in Indonesia. This condition not only affects physical health but also requires patients to make significant lifestyle changes to maintain stable blood glucose levels. Efforts to adopt a healthy lifestyle such as regulating diet, exercising regularly, and managing stress are often met with various challenges. In this context, family support plays a crucial role in helping patients adapt and remain consistent in self-management. This study aims to describe the experiences of type 2 diabetes patients in maintaining a healthy lifestyle and the forms of family support they receive. A qualitative phenomenological approach was used, involving three participants undergoing outpatient treatment at RSUD Sultan Iskandar Muda Nagan Raya. Data were collected through in-depth interviews, observations, and documentation, then analyzed thematically. The findings show that patients face challenges in maintaining dietary control, consistent exercise, and emotional balance. However, family support such as reminding patients to take medication, providing healthy meals, and offering emotional motivation serves as a key factor that strengthens patients’ commitment to a healthy lifestyle. The study concludes that the success of diabetes management is highly influenced by active family involvement. Therefore, educational and health intervention programs should integrate families as essential partners in supporting patients with diabetes.

Skin aging is a natural process that cannot be avoided, but it can be slowed down through proper skin care. The use of natural face masks is one of the safe, affordable, and relatively non-invasive treatment alternatives without long-term side effects. The bandotan plant (Ageratum conyzoides L.) is a weed that grows wild in the Cemani Village area, Sukoharjo Regency. Although often considered worthless, this plant actually contains active compounds such as flavonoids, tannins, and saponins that have the potential to be antioxidants. Therefore, this service activity aims to provide counseling and training to the people of Cemani Village regarding the manufacture of face masks made from bandotan plants. This program is carried out with several procedural stages, starting from the interpretation of problems on the land, followed by the preparation of the timeline for the implementation of activities, then counseling and ending with a workshop session on the procedure for making antiaging masks for bandotan herbs. The program ended with an assessment of the evaluation of the activities. This activity was attended by 20 participants of the Cemani village PKK mobilization team. Based on the pretest and posttest scores, there was an increase in public knowledge about the program carried out with an average of 80 pretests and an increase in the average percentage of posttest scores up to 95.83. In the assessment of the questionnaire, public satisfaction with the implementation of the activity was classified as very satisfied with a score of 92.67.

Skin aging is a natural process that cannot be avoided, but it can be slowed down through proper skin care. The use of natural face masks is one of the safe, affordable, and relatively non-invasive treatment alternatives without long-term side effects. The bandotan plant (Ageratum conyzoides L.) is a weed that grows wild in the Cemani Village area, Sukoharjo Regency. Although often considered worthless, this plant actually contains active compounds such as flavonoids, tannins, and saponins that have the potential to be antioxidants. Therefore, this service activity aims to provide counseling and training to the people of Cemani Village regarding the manufacture of face masks made from bandotan plants. This program is carried out with several procedural stages, starting from the interpretation of problems on the land, followed by the preparation of the timeline for the implementation of activities, then counseling and ending with a workshop session on the procedure for making antiaging masks for bandotan herbs. The program ended with an assessment of the evaluation of the activities. This activity was attended by 20 participants of the Cemani village PKK mobilization team. Based on the pretest and posttest scores, there was an increase in public knowledge about the program carried out with an average of 80 pretests and an increase in the average percentage of posttest scores up to 95.83. In the assessment of the questionnaire, public satisfaction with the implementation of the activity was classified as very satisfied with a score of 92.67.

This study aims to: (1) examine the effect of an entrepreneurship program using a Design thinking approach on the entrepreneurial spirit of Grade V students at UPT SPF SD Inpres Baraya 1, Makassar City, and (2) examine the effect of an entrepreneurship program using a Design thinking approach on student independence of Grade V students at UPT SPF SD Inpres Baraya 1, Makassar City. This research employed a quantitative approach with a quasi-experimental method using a Non-Equivalent Control Group Design. The research subjects consisted of two groups: an experimental group that received an entrepreneurship program based on Design thinking and a control group that did not receive the treatment. Data were collected using questionnaires measuring students’ entrepreneurial spirit and independence, supported by documentation. Data analysis was conducted using descriptive statistics, classical assumption tests, and hypothesis testing through an independent samples t-test. The results indicate that the entrepreneurship program using a design thinking approach had a significant positive effect on students’ entrepreneurial spirit and independence. The independent samples t-test revealed that the program significantly improved students’ entrepreneurial spirit (p = 0.002 < 0.05) compared to the control group. Likewise, a very significant effect was found on student independence, with a significance value of p = 0.001 < 0.05. These findings confirm that the application of a design thinking–based entrepreneurship program effectively enhances key entrepreneurial attributes, including creativity, initiative, responsibility, and independence among fifth-grade elementary school students.

Osteoarthritis is a progressive degenerative joint disease characterized by cartilage damage, chronic inflammation, and functional limitation. Current treatments mainly focus on symptom relief and mechanical correction, with limited ability to restore the biological environment of the joint. Recently, mesenchymal stem cell derived secretome has emerged as a promising cell free regenerative therapy with anti-inflammatory and tissue-repair potential. This study aimed to systematically review the role of mesenchymal stem cell secretome in osteoarthritis management, both as an intra-articular therapy and as an adjuvant following surgical intervention. A literature review was conducted on relevant preclinical and early clinical studies published over the past decade. The selected articles were analyzed to evaluate therapeutic mechanisms and clinical implications. The findings indicate that intra articular administration of secretome reduces inflammatory mediators, suppresses catabolic enzyme activity, and improves cartilage integrity in various osteoarthritis models. Early clinical evidence also suggests improvements in pain and joint function, especially in patients with mild to moderate disease. Furthermore, secretome shows potential as an adjuvant therapy after surgery by supporting biological recovery of joint tissues. Overall, mesenchymal stem cell secretome represents a promising component of a multimodal strategy for osteoarthritis management, although further clinical trials are required to confirm its efficacy and safety.

Nephrotic syndrome (NS) is a kidney disorder characterized by massive proteinuria, hypoalbuminemia, edema, and hypercholesterolemia, most commonly occurring in children. This disease can be caused by various conditions, such as minimal change disease, FSGS, or lupus nephritis. This case report discusses a 16-year-old boy who experienced nephrotic syndrome with symptoms of swelling throughout his body, accompanied by decreased appetite and a productive cough. The patient presented with complaints of swelling throughout his body that began 7 days after hospitalization and was accompanied by coughing and shortness of breath. A physical examination revealed massive edema, abdominal hypertympany, and shifting dullness. Laboratory tests revealed proteinuria, hypoalbuminemia, and decreased serum albumin. Other supporting tests confirmed nephrotic syndrome. The patient received medication therapy including diuretics, corticosteroids in the form of methylprednisolone, and albumin. Nephrotic syndrome in children can develop gradually and requires management that includes steroids, diuretics, and close monitoring of kidney function and electrolytes. Early detection and appropriate treatment can help improve the patient's prognosis.

The decline in seed quality due to storage beyond the shelf life is a major problem in rice cultivation. One effort that can be made to improve seed viability is through invigoration techniques using natural ingredients, such as bean sprout extract (Phaseolus radiatus), which contains growth hormones. This study aims to analyze the effect of bean sprout extract on the viability of Ciherang rice seeds that have exceeded their shelf life and to determine the best treatment. The study was conducted from August to November 2024 at the Biology Laboratory of the UPTD Seed Center, Supervision and Certification of Agricultural Seeds of Gorontalo Province. The study used a two-factor Randomized Block Design (RBD) with bean sprout age (3, 5, and 7 days after sowing) and bean sprout extract concentration (20 g/L, 40 g/L, and 60 g/L) as factors, with four replications. The parameters observed included germination rate, maximum growth potential, and sprout length. The data were analyzed using ANOVA and DMRT post-hoc test at a 5% level. The results showed that bean sprout extract had a significant effect on all observed parameters. The treatment of 5-day-old bean sprouts with a concentration of 20 g/L gave the best results with a germination rate of 95.5%, maximum growth potential of 98.5%, and the highest sprout length. Sprout extract has the potential to be used as a natural alternative to improve the quality of rice seeds that have passed their storage period.

This study aims to determine the effect of the Talking Stick model assisted by Mystery Box learning media on learning motivation and learning outcomes in IPAS of fifth-grade students at SD Inpres Borongunti, Bajeng District, Gowa Regency. This study employed a quantitative approach with a pre-experimental design. The research subjects consisted of 31 students. Data were collected using a learning motivation questionnaire and learning outcomes tests, while data analysis was conducted through normality testing and hypothesis testing using the t-test. The results showed that prior to the implementation of the Talking Stick model assisted by Mystery Box media, students’ learning motivation was predominantly in the low and moderate motivation categories. After the treatment was applied, students’ learning motivation increased significantly, with all students categorized as motivated and highly motivated. The t-test results for learning motivation indicated a significance value of 0.002 < 0.05, thus H₁ was accepted. In addition, students’ IPAS learning outcomes also showed a significant improvement, as indicated by an increase in the mean score from 66 in the pretest to 86 in the posttest, with learning mastery increasing from 42% to 100%. The t-test results for learning outcomes showed a significance value of 0.000 < 0.05, thus H₁ was accepted. Based on these findings, it can be concluded that the Talking Stick model assisted by Mystery Box learning media has a significant effect on improving learning motivation and learning outcomes in IPAS of fifth-grade students at SD Inpres Borongunti, Bajeng District, Gowa Regency.

Hemangioma is the most common benign vascular tumor in infancy and is generally characterized by a proliferative phase followed by spontaneous involution. Although most cases resolve without intervention, treatment is required when hemangiomas cause functional impairment, ulceration, or life-threatening complications. Lingual hemangioma is a rare presentation and may result in significant feeding difficulties and airway compromise, requiring prompt and multidisciplinary management. This study aims to report the comprehensive management of a refractory lingual hemangioma in an infant, emphasizing diagnostic evaluation, therapeutic strategy, and nutritional support. A six-month-old female infant presented with a lingual hemangioma associated with progressive feeding difficulties. Prior to initiating therapy, a thorough diagnostic workup was performed, including echocardiography to assess cardiac function, magnetic resonance imaging (MRI) to evaluate lesion extent, and computed tomography angiography (CT-angiography) to delineate vascular anatomy. The patient initially received oral propranolol as first-line therapy; however, due to an inadequate response, combination chemotherapy with Bleomycin–Vincristine (BV) was initiated. To minimize the risk of toxicity, a 50% dose reduction was applied. Clinical evaluation demonstrated a favorable therapeutic response, with a reduction in lesion size and improvement in feeding ability after 10 weeks of treatment. No severe adverse effects were observed during the treatment period. To ensure adequate nutritional intake and support growth, enteral nutrition via a nasogastric tube (NGT) was provided throughout the course of therapy. This case highlights the importance of comprehensive diagnostic assessment, individualized treatment planning, and close monitoring in refractory hemangioma. In addition, optimal nutritional support plays a crucial role in overall patient outcomes. A multidisciplinary approach is essential for the successful management of complex infantile hemangiomas with functional complications.

Permanent tooth loss is a common oral health problem experienced by patients. This condition can be caused by pathological conditions such as tooth decay, leading to tooth extraction. Rehabilitation treatment for partial posterior tooth loss aims to restore masticatory function, maintain occlusal relationships and periodontal health, and improve aesthetics. A 34-year-old man came with a complaint that his lower right posterior tooth had been extracted and wanted a permanent dentures to replace his missing tooth. The intraoral and periapical radiograph examination revealed that 46 was missing, and 47 had enamel caries. The diagnosis for 46 was determined to be partial edentulous. The treatment plan was a PFM fixed-fixed bridge with a sanitary pontic for 46, a rigid connector, and a full crown retainer for 45 and 47. In this case, the choice of PFM bridge is based on several considerations, i.e., high chewing loads, relatively low cost, and high long-term success. The PFM bridge has been the primary choice for posterior tooth rehabilitation, due to its durability and cost-effectiveness.

The increasing need for insulation in electric power systems encourages the discovery of high-performance and sustainable dielectric materials. This study presents a Literature Review of biomass-based composite insulator research from 2018-2025 to synthesize the effect of filler type and treatment on the electrical, thermal, and mechanical properties of polymer composites. Literature was analyzed from reputable databases with inclusion criteria, and thematic analysis data extraction. Processing methods generally include washing, acid/alkali treatment, calcination, and advanced production techniques such as sol-gel and ultrasonication, integration of biomass fillers especially at low fractions (3-7%). The results show 1) the dominance of the use of rice husk as a source of biosilica for the main matrix filler of the insulator. 2) the performance of biomass composite insulators is highly dependent on the quality of purification, particle size, and surface modification of the filler. 3) there is a significant increase in the insulator's breakdown strength, resistivity, and thermal stability with the addition of biomass fillers to the main matrix. 4) the long-term stability of biomass materials against humidity and thermal aging has not been evaluated in depth.