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Medical students need to take the Competence test as Doctor Profession Program (UKMPPD) to be passed and earned their medical profession. Exams are one of the most common stressors experienced by medical students and the body will respond to these stressors in the form of feelings of depression or anxiety. Anxiety and depression itself can affect student performance during exam preparation. The purpose of this study was to determine the relationship between anxiety and depression on the preparation of the Professional Doctoral Program Competency Test (UKMPPD) for students of the Faculty of Medicine, University of Pattimura. The method used is quantitative analysis with cross sectional research design and total sampling technique. The sample is all the student population of the Faculty of Medicine, University of Pattimura who meet the inclusion and exclusion criteria, totaling 90 respondents. The results showed that the majority of respondents experienced mild anxiety symptoms, which is 37% during the CBT exam and 34% during the OSCE exam. The majority of respondents also did not experience depression, which is 68% during the CBT and 70% during the OSCE and the majority had an optimal level of preparation for UKMPPD, which is 63% during the CBT and 64% during the OSCE. Data analysis using the chi square test showed a significant relationship between anxiety symptom and the level of preparation for UKMPPD both CBT (p=0.030) and OSCE (p=0.012). There was no significant relationship between depression symptom and the level of preparation for UKMPPD for both CBT (p=0.123) and OSCE (p=0.07). It can be concluded that there is a significant relationship between anxiety and preparation for UKMPPD, but there is no significant relationship between depression and preparation for UKMPPD.

Postpartum depression is a postpartum mental health disorder that significantly impacts maternal well-being, infant development, and family functioning. The high prevalence of postpartum depression in Indonesia is due to limited access to health services, low mental health literacy, and social stigma in the community. This indicates a significant gap between the need for maternal mental health services and the availability of existing interventions, making education a crucial component in efforts to prevent postpartum depression early. This study aims to analyze the prevention of postpartum depression in postpartum mothers through telenursing-based education and screening using the Edinburgh Postnatal Depression Scale (EPDS) in the community. A descriptive case study design was used, involving one respondent, a 25-year-old primigravida mother residing in the Bantul area. The intervention was implemented online via WhatsApp and video calls, including structured health education on postpartum psychological changes, adaptive coping strategies, and the importance of social support. The intervention also included daily remote monitoring of the respondent's condition via the WhatsApp mobile application. The EPDS was administered as a pre-test and post-test to evaluate changes in the respondent's psychological condition. The findings showed a significant decrease in the EPDS score from 16 (moderate depression) to 6 (minimal depression), indicating significant psychological improvement. These results imply that integrating EPDS screening, structured health education, and daily monitoring is an effective and accessible community-based approach to preventing postpartum depression, particularly for mothers with limited mobility and access to health services.

Mindfulness intervention therapy is a psychotherapy that can be used to reduce depressive symptoms. This study aims to determine whether mindfulness therapy contributes to reducing the level of depression in patients cancer at the Cipto Mangunkusumo Hospital, Jakarta. The research design used was the experimental design of the one group pretest-posttest design. The total number of samples used for the population was 30 people who met the criteria for depression. Relevant data was collecterd through clinical interviews, observations and psychological test. The Beck Depression Inventory II (BD-II) questionnaire was used to collect data for this study. According to the Wilcoxon analysis, the results were statistically significant p = 0.000, indicating a large effect size in reducing depressive symptoms with mindfulness therapy. These results are supported by improved patients understanding of depression and mindfulness concepts, as well as enhanced abilities in adapting emotional coping strategies. The results of qualitative analysis showed that subjek felt more happy, be positive, not hopeless, effective communication skills and be able to resolve their problems. This research can make a significant contribution to efforts to prevent and treat depression in cancer patients, improving their quality of life through increasing mindfulness.

This study aims to examine the relationship between family support and depression levels among the elderly in Pejuang Village, Bekasi City, through a descriptive-narrative literature review. The review analyzed relevant scientific articles discussing family support, social support, and depression in older adults. Literature was selected based on the suitability of the elderly population, the presence of family or social support variables, and the measurement of depressive symptoms or depression levels. The analysis compared each article’s objectives, research design, respondent characteristics, instruments, findings, and conclusions. The results indicate that most studies found a relationship between family support or social support and depression among the elderly. Adequate family support, including emotional, instrumental, informational, and appraisal support, helps older adults feel cared for, valued, secure, and better able to adapt to the aging process. Preliminary findings at the Elderly Posyandu in Pejuang Village also show variations in family support and depression levels among elderly participants. Conversely, limited family support may increase loneliness, psychological distress, and depressive symptoms. Therefore, family support functions as a protective factor in reducing depression risk among older adults. Strengthening the involvement of families, health workers, and elderly posyandu cadres is necessary as a promotive and preventive strategy to maintain psychological well-being through education, early detection, and sustainable community-based assistance for vulnerable elderly groups living in community and family environments.

Hypertension has become a chronic disease known as the silent killer because it often does not show symptoms but can cause serious complications such as stroke, heart disease, and kidney failure. According to WHO, hypertension is one of the leading causes of death worldwide and its prevalence continues to rise. Sleep disturbances can increase sympathetic nervous system activity and stress hormones, which impact blood pressure elevation. Depression is characterized by prolonged feelings of sadness, loss of interest, and decreased energy. Physiologically, depression can increase stress hormones and cause autonomic nervous system imbalance, leading to elevated blood pressure. To determine the relationship between sleep pattern disturbances and depression levels with blood pressure in hypertensive patients in the outpatient department of RS Permata Medika Semarang. Quantitative research with a correlational design using a cross-sectional approach. The sampling technique used was consecutive sampling with a sample size of 79 respondents. The instruments used are the PSQI questionnaire for sleep pattern disturbances and the DASS-42 for depression levels. Ethics test no 03/EC-LPPM/UWHS/II-2026. Data analysis used the Spearman Rank test. The research results show that there is a significant relationship between sleep pattern disturbances and blood pressure in hypertensive patients (p=0.000; rho=0.826). Respondents with poor sleep patterns mostly have high blood pressure, indicating a very strong and positive relationship, where the worse the sleep pattern, the more uncontrolled the blood pressure tends to be. Additionally, there is a significant relationship between the level of depression and blood pressure (p=0.000; rho=0.808). Respondents with severe and very severe depression mostly have high blood pressure, which means that the higher the level of depression, the more the blood pressure increases or becomes uncontrolled. There is a relationship between sleep pattern disturbances and depression levels with blood pressure in hypertensive patients in the outpatient department of Permata Medika Hospital Semarang.

Depression is one of the most common mental health problems experienced by older adults and is influenced by various factors, including individual characteristics and chronic disease conditions. This study aims to determine the influence of age, gender, and chronic disease history on the incidence of depression among older adults residing at Roujin Home Asahi No Ie, Japan. The study used a quantitative method with a cross-sectional design. The population consisted of all elderly individuals living at Roujin Home Asahi No Ie, and the sampling technique used was total sampling. The Geriatric Depression Scale (GDS) was utilized as the instrument to measure depression levels. Data were analyzed using univariate and bivariate analyses with the Chi-Square test. The results showed a significant relationship between age and depression levels (p = 0.001), indicating that older age increases the risk of depression. Gender also demonstrated a significant association with depression (p = 0.015), showing differences in vulnerability between male and female elderly individuals. In addition, a significant relationship was found between chronic disease history and depression (p = 0.002), indicating that elderly individuals with chronic illnesses are more likely to experience depression. Based on these findings, it can be concluded that age, gender, and chronic disease history significantly influence depression among older adults. These results are expected to support the development of preventive strategies and geriatric nursing interventions to improve mental health and quality of life among elderly individuals in nursing home environments.

Postpartum depression (PPD) is a common and serious mental health disorder for mothers after givingbirth, which is a public mental health problem because it not only has a direct impact on the baby, but also on the family. The most common symptoms of PPD are overwhelming sadness, feelings of hopelessness and helplessness, moodiness, an inability to experience joy with the baby, serve anxienty, loss of appetite, poor concentration and memory, sleep disturbances, prolonged fatigue, and suicidal ideation (American Psychological Association, 2013). The design used in this study was quantitative by measuring the prevalence of postpartum depression in postpartum mothers using the EPDS form. The research was conducted at Gandapura Community Health Center, this location wa used as the research site because it had not been exposed at all regarding the use of the EPDS form as part of the initial assessment of midwifery services. A population is all elements that meet certain criteria for inclusion in a study. The population in this study was all postpartum mothers who gave birth in the obstetrics ward. The sample criteria in this study are divided into two, namely inclusion criteria and exclusion criteria. Conclusion: Postpartum guidance provided to mothers influences the risk of postpartum depression. Postpartum women who receive assistance are less likely to experience postpartum depression, and mothe who do not receive assistance are depression.

Pemanfaatan tanaman obat sebagai sumber agen neurofarmakologis alami semakin mendapat perhatian seiring meningkatnya prevalensi gangguan sistem saraf dan keterbatasan penggunaan obat sintetis. Salah satu tanaman yang berpotensi namun masih terbatas kajian ilmiahnya adalah Kesambi (Schleichera oleosa), yang secara tradisional digunakan untuk berbagai keperluan pengobatan. Penelitian ini bertujuan mengevaluasi pengaruh variasi konsentrasi ekstrak daun Kesambi terhadap efek neurofarmakologi, serta mengidentifikasi pola respons dosis dan konsentrasi paling efektif dalam memodulasi sistem saraf pusat dan otonom. Penelitian ini menggunakan desain eksperimental dengan hewan uji yang dibagi ke dalam kelompok kontrol dan kelompok perlakuan. Ekstrak daun Kesambi diperoleh melalui metode maserasi menggunakan pelarut akuades dan diberikan secara per oral pada konsentrasi 1%, 2%, dan 4%. Evaluasi efek neurofarmakologis dilakukan melalui skrining perilaku terhadap delapan parameter, yaitu parasimpatomimetik, stimulasi sistem saraf pusat, depresi sistem saraf pusat, simpatolitik, relaksasi otot, simpatomimetik, parasimpatiolitik, dan analeptik. Hasil penelitian menunjukkan bahwa ekstrak daun Kesambi menimbulkan variasi respons neurofarmakologis yang dipengaruhi oleh konsentrasi. Konsentrasi 4% memberikan efek paling dominan pada sebagian besar parameter, khususnya depresi sistem saraf pusat, relaksasi otot, dan modulasi sistem saraf otonom, sedangkan konsentrasi 2% menunjukkan efek stimulasi sistem saraf pusat yang optimal. Temuan ini menunjukkan potensi ekstrak daun Kesambi sebagai neuromodulator.  

Pemanfaatan tanaman obat sebagai sumber terapi berbasis bahan alam masih menjadi fokus penting dalam penelitian, khususnya pada tanaman yang telah lama digunakan secara empiris namun memiliki keterbatasan bukti ilmiah. Rambutan (Nephelium lappaceum L.) merupakan salah satu tanaman yang secara tradisional dimanfaatkan untuk mengatasi berbagai gangguan kesehatan, tetapi kajian farmakologis terhadap efek daun rambutan pada sistem saraf masih terbatas. Penelitian ini bertujuan untuk mengevaluasi aktivitas neurofarmakologis serbuk simplisia daun rambutan terhadap sistem saraf pusat dan sistem saraf otonom pada berbagai konsentrasi. Penelitian ini merupakan studi eksperimental laboratorium yang menggunakan mencit sebagai hewan uji. Serbuk simplisia daun rambutan diberikan secara oral pada konsentrasi 1%, 2%, dan 3%. Parameter neurofarmakologis yang diamati meliputi aktivitas parasimpatomimetik, parasimpatolitik, simpatomimetik, simpatolitik, aktivitas analeptik, stimulasi dan depresi sistem saraf pusat, serta relaksasi otot. Pengamatan dilakukan berdasarkan perubahan perilaku dan respons fisiologis hewan uji.

The postpartum period is a critical transitional phase during which women are vulnerable to psychological disturbances, particularly postpartum depression. Psychological distress may undermine maternal confidence, including the perceived ability to breastfeed effectively. This study aimed to examine the relationship between breastfeeding self-efficacy and postpartum depression among postpartum mothers. A quantitative cross-sectional design was employed involving 45 respondents selected through total sampling. Depressive symptoms were assessed using the Edinburgh Postnatal Depression Scale (EPDS), while breastfeeding self-efficacy was measured using the Breastfeeding Self-Efficacy Scale-Short Form (BSE-SF). Data were analyzed using Spearman’s Rank correlation test with a significance level of 0.05. The results demonstrated a statistically significant and strong negative correlation between breastfeeding self-efficacy and postpartum depression (r = –0.616; p < 0.05). Mothers with higher depressive symptoms tended to report lower levels of breastfeeding self-efficacy. These findings highlight the importance of integrating mental health screening and breastfeeding support into postpartum care to strengthen maternal confidence and improve breastfeeding outcomes.  

Postpartum depression is a mood disorder that occurs in mothers after childbirth, with symptoms that can appear from pregnancy until 4 weeks postpartum. This condition negatively impacts the psychological health of the mother and the development of the baby. This study aims to analyze factors associated with the risk of postpartum depression. The method used was quantitative with an analytical survey design through a cross-sectional approach. Data collection was carried out using the Edinburgh Postnatal Depression Scale (EPDS) questionnaire consisting of 10 questions. The results of the validity test showed a calculated r value of > 0.3610 and the reliability test obtained a Cronbach's alpha value of 0.67. The study sample consisted of 42 respondents selected using a total sampling technique, with inclusion criteria of mothers aged ≥18 years, in the period <6 weeks postpartum, and willing to be respondents. Data analysis used the chi-square test. The results showed that all variables had a significant relationship with the risk of postpartum depression (p < 0.05). These variables include age (p=0.040), education (p=0.018), occupation (p=0.011), history of depression (p=0.024), complications (p=0.017), economic status (p=0.048), parity (p=0.016), type of delivery (p=0.006), husband's support (p=0.000), and family support (p=0.028). Therefore, it can be concluded that demographic, obstetric, and social support factors play an important role in the risk of postpartum depression. These results are expected to form the basis for prevention efforts and early intervention to improve postpartum maternal mental health.

Pemanfaatan tanaman obat sebagai sumber fitofarmaka terus berkembang seiring meningkatnya kebutuhan akan agen terapeutik berbasis bahan alam yang aman. Salah satu tanaman yang berpotensi dikembangkan adalah daun soliti (Wrightia arborea), yang diketahui mengandung senyawa bioaktif seperti flavonoid, alkaloid, saponin, terpenoid, dan glikosida. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak daun soliti terhadap respons fisiologis dan perilaku mencit sebagai model hewan uji. Penelitian menggunakan desain eksperimental laboratorik dengan rancangan post-test only. Ekstrak daun soliti diperoleh melalui metode maserasi menggunakan pelarut etanol dan dibuat dalam konsentrasi 1%, 2%, dan 4%. Hewan uji berupa mencit putih jantan dibagi ke dalam kelompok perlakuan, kemudian diamati respons fisiologis dan perilakunya. Parameter yang diamati meliputi parasimpatomimetik, stimulasi dan depresi sistem saraf pusat, simpatolitik, relaksasi otot, parasimpatolitik, serta analeptik. Hasil penelitian menunjukkan bahwa ekstrak daun soliti memberikan pengaruh yang bervariasi terhadap respons fisiologis dan perilaku mencit dengan pola dosis-respons yang tidak linier. Konsentrasi 1% menunjukkan efek tertinggi pada beberapa parameter, konsentrasi 2% menunjukkan penurunan respons, sedangkan konsentrasi 4% meningkatkan kembali respons tertentu, khususnya sistem saraf otonom. Temuan ini mengindikasikan adanya efek bifasik. Penelitian ini menyimpulkan bahwa ekstrak daun soliti berpotensi dikembangkan sebagai kandidat fitofarmaka, namun diperlukan penelitian lanjutan untuk mengkaji mekanisme kerja dan aspek keamanannya.  

Depression is one of the mental health problems that often arise in patients with chronic diseases, such as diabetes mellitus, hypertension, and chronic kidney failure. This condition not only impacts the patient's quality of life, but also affects the treatment process and the burden on the family. However, mental health literacy in the community is still low, so targeted preventive and curative efforts are needed. The Community Service Program (PKM) aims to improve people's mental health through educational interventions with scientific booklet media that are easy to understand and apply. The activity method is carried out in a participatory manner, including the preparation stage, socialization, educational implementation, and evaluation. Education is provided to the community with a focus on preventing depression through a healthy lifestyle, stress management skills, and early intervention efforts by seeking professional support. Evaluation is carried out through pre-post tests, observations, and group discussions. The results of the activity showed an increase in public knowledge about depression, a change in attitudes to be more open in expressing feelings, as well as practical skills in relaxation, maintaining sleep patterns, and building social support. Participants also better understand the importance of seeking professional help when depressive symptoms are getting worse. The conclusion of this PKM is that the scientific booklet has proven to be effective as a preventive and curative educational intervention medium, and can be an innovative strategy in improving the mental health of people affected by chronic diseases.

Penelitian ini bertujuan untuk mengkaji dampak pola asuh otoriter terhadap perkembangan sosial dan emosional anak usia dini. Perkembangan sosial emosional anak usia dini sangat penting karena membentuk sikap, nilai, dan perilaku mereka di masa depan. Studi kepustakaan ini menelaah berbagai teori dan penelitian relevan untuk menganalisis bagaimana pola asuh otoriter, yang menekankan kontrol ketat dan kepatuhan, memengaruhi perkembangan anak. Hasil kajian menunjukkan bahwa pola asuh otoriter dapat menghambat perkembangan regulasi emosi anak, meningkatkan risiko kecemasan dan depresi, serta memicu reaksi defensif yang mengarah pada perilaku eksternalisasi seperti agresi atau internalisasi seperti isolasi sosial. Dampak gender juga terlihat, di mana anak perempuan cenderung memendam emosi menjadi apatis atau cemas, sementara anak laki-laki lebih mengeksternalisasi menjadi ledakan emosi. Selain itu, faktor budaya seperti nilai kolektivisme di Indonesia dapat memperburuk dampak negatif pola asuh ini. Dampak jangka panjang dari pola asuh otoriter meliputi masalah akademik dan sosial di sekolah dasar, serta peningkatan risiko gangguan mental di masa dewasa. Penelitian ini menekankan pentingnya intervensi untuk mencegah anak-anak yang diasuh secara otoriter mengulangi pola tersebut di generasi berikutnya.

Penurunan kognitif berkorelasi kuat dengan penurunan kualitas hidup secara keseluruhan, meningkatkan risiko isolasi sosial, depresi, dan ketergantungan sehingga perlu adanya Upaya pencegahan penurunan fungsi kognitif. Hasil wawancara dengan Kepala Puskesmas Sekaran menyampaikan bahwa dari 5 Kelurahan yang dibina oleh Puskesmas Sekaran, Kelurahan Sukorejo termasuk wilayah yang memiliki masalah kesehatan yang kompleks. Masalah kesehatan terkait lansia perlu mendapatkan perhatian yang tidak kalah penting juga. Kesehatan lansia yang di bawah pengelolaan posyandu lansia di daerah Kelurahan Sukerejo Deliksari telah berjalan dengan baik. Hanya saja wilayah tersebut terkait penanganan masalah kesehatan kognitif lansia masih perlu mendapatkan perhatian yang lebih. Salah satu gangguan fungsi kognitif pada lansia adalah demensia. Penanganan kesehatan terkait demensia di wilayah tersebut tidak ada, hal ini dikarenakan kader posyandu lansia menganggap masalah demensia atau pikun meruapakan yang wajar dan normal bagi lansia. Maka diperlukan upaya promotif dan pencegahan dengan diadakannya pengabdian masyarakat terkait peran kader dalam deteksi dini lansia dengan demensia. Setelah diberikan pendidikan kesehatan Lansia mengatakan bahwa perlu melakukan kegiatan untuk tetap menjaga daya ingat diusia senja.

This study aims to describe the level of anxiety, stress, and depression in women undergoing In Vitro Fertilization (IVF) program and to see the distribution of psychological disorders based on sociodemographic characteristics and the stage of IVF program undertaken. The design of this study was descriptive quantitative with purposive sampling technique on 28 women who were undergoing IVF cycles in infertility clinics in Yogyakarta Special Region. Data were collected online through a questionnaire containing Hamilton Anxiety Rating Scale (HARS), Perceived Stress Scale (PSS), and Beck Depression Inventory-II (BDI-II) instruments. Descriptive analysis showed that most respondents experienced moderate anxiety (42%), mild stress (38%), and mild depression (36%). The analysis also showed that sociodemographic characteristics, such as age older than 35 years, non-working employment status, and low education, had a higher tendency towards psychological disorders. In addition, certain phases of IVF, such as the waiting phase after embryo transfer, appeared to be associated with increased levels of anxiety and stress. This study emphasizes the importance of more intensive psychological support, especially for women who are in the more stressful stages of IVF, as well as for those with sociodemographic risk factors that increase their vulnerability to psychological disorders.

Penelitian ini mengkaji pengaruh nilai tukar dan suku bunga terhadap return saham perusahaan sektor pertambangan yang tercatat di Bursa Efek Indonesia selama periode 2022-2024. Sektor pertambangan merupakan salah satu sektor yang paling terdampak oleh fluktuasi ekonomi global, terutama perubahan nilai tukar dan suku bunga. Penelitian ini menggunakan metode kuantitatif dengan pendekatan regresi linier berganda, serta memanfaatkan data sekunder dari Bank Indonesia dan Bursa Efek Indonesia. Hasil analisis menunjukkan bahwa nilai tukar berpengaruh negatif dan signifikan terhadap return saham, yang berarti depresiasi rupiah cenderung menurunkan kinerja saham perusahaan pertambangan. Sebaliknya, suku bunga tidak menunjukkan pengaruh yang signifikan. Temuan ini memberikan implikasi penting bagi investor, analis keuangan, dan pembuat kebijakan dalam memahami risiko makroekonomi dan merumuskan strategi investasi di sektor pertambangan.

Dysmenorrhea atau dismenore didefinisikan sebagai menstruasi yang menyakitkan serta keluhan ginekologi paling umum terjadi pada wanita usia muda yaitu usia remaja. Keluhan yang dirasakan yaitu nyeri atau kram di perut bagian bawah yang muncul sebelum atau saat menstruasi. Dismenore berpengaruh terhadap gangguan psikologis seperti depresi, kecemasan dan somatisati yang dapat menghambat perkembangan pada remaja. Tujuan penelitian ini untuk mengetahui pengaruh kejadian dysmenorrhea terhadap perkembangan remaja putri. Jenis penelitian ini survei analitik observasional melalui pendekatan cross seictional stuidy. Populasi adalah seluruh siswi sebanyak 42 orang serta teknik pengambilan sampel total sampling. Instrumen pengumpulan data menggunakan lembar kuesioner. Analisis data yaitu analisa univariat dan bivariat dengan menggunakan uji chi-square. Hasil penelitian terdapat pengaruh kejadian dysmenorrhea terhadap perkembangan sosial remaja putri dengan nilai p = 0,032, terdapat pengaruh kejadian dysmenorrhea terhadap perkembangan emosional remaja putri dengan nilai p = 0,014, terdapat pengaruh kejadian dysmenorrhea terhadap perkembangan kognitif remaja putri dengan nilai p = 0,047, terdapat pengaruh kejadian dysmenorrhea terhadap perkembangan moral remaja putri dengan nilai p = 0,029. Kesimpulan penelitian ini yaitu ada pengaruh kejadian dysmenorrhea terhadap perkembangan remaja putri.

This study aims to evaluate the relationship between spiritual activity and depression levels in the elderly at the Regional Technical Implementation Unit (UPTD) Rumoh Seujahtera Geunaseh Sayang (RSGS), Ulee Kareng District, Banda Aceh. The study used a quantitative design with a population of 55 elderly individuals and a sample of 33 respondents aged 60–74 years, selected through purposive sampling. The instruments used included the Daily Spiritual Experience Scale (DSES) with an internal consistency of (α = 0.9) and the Geriatric Depression Scale (GDS-15) with 92% sensitivity. The results showed that elderly individuals with low spiritual levels tended to experience more severe depression, with 25% of them experiencing severe depression. Meanwhile, 66.7% of those with moderate spiritual levels experienced mild depression, and 60.6% of those with high spiritual levels were in the normal category or showed no depressive symptoms. Bivariate analysis revealed a significant relationship between spiritual activity and depression levels in the elderly with a p-value of 0.000. The conclusion of this study is that involvement in spiritual activities has a significant impact on depression levels in the elderly at UPTD RSGS, Ulee Kareng District, Banda Aceh. This study provides an understanding of the importance of spiritual activity in reducing depression in the elderly, which can serve as a basis for developing spiritually-based mental health interventions in elderly communities.

This research is a quantitative study with a descriptive correlational design using a cross-sectional approach. The purpose of this study was to determine the relationship between depression level and self-efficacy among patients with kidney failure treated in the internal medicine ward of RS QIM Batang. The sample consisted of 40 respondents selected using purposive sampling from the population of chronic kidney failure patients undergoing hemodialysis. The instruments used were the Hamilton Depression Rating Scale (HDRS) to measure depression and a 25-item self-efficacy questionnaire to assess patients’ confidence. Data analysis was performed using the Spearman Rank test. The results showed that most respondents were in the normal depression category (31.4%), while 24.8% experienced severe depression. Regarding self-efficacy, the majority of respondents were in the high category (43.8%). The Spearman Rank test revealed a correlation coefficient (rho) of -0.881 with a p-value of 0.000 (p < 0.05), indicating a very strong and statistically significant negative relationship between depression and self-efficacy. This means that the higher the patients’ self-efficacy, the lower their level of depression. The conclusion of this study is that there is a very strong and significant relationship between depression level and self-efficacy among patients with kidney failure treated in the internal medicine ward of RS QIM Batang.