Publication Search

Tomato (Solanum lycopersicum) is an economically important crop whose productivity is increasingly constrained by drought stress under changing climatic conditions. Conventional breeding for drought tolerance is often slow because this trait is quantitatively inherited and strongly influenced by environmental factors. Molecular markers, particularly Simple Sequence Repeats (SSRs), have become valuable tools for improving selection efficiency and accelerating breeding progress. This review examines the role of SSR markers in the development of drought-tolerant tomato cultivars. The physiological, biochemical, and molecular responses of tomato to drought stress, including growth reduction, photosynthetic impairment, osmotic adjustment, hormonal regulation, and oxidative stress responses, are briefly discussed. The genetic characteristics of SSR markers, including their high polymorphism, co-dominant inheritance, and multi-allelic nature, are highlighted as key advantages for genetic analysis and breeding applications. Furthermore, the review synthesizes recent findings on the use of SSR markers for genetic diversity assessment, Quantitative Trait Loci (QTL) mapping, and identification of genomic regions associated with drought-related traits such as relative water content, chlorophyll stability, root architecture, and proline accumulation. The application of SSRs in Marker-Assisted Selection (MAS), including marker-assisted backcrossing and QTL pyramiding, is also discussed. Finally, the review evaluates the continuing relevance of SSR markers in the genomic era, emphasizing their complementary role alongside Single Nucleotide Polymorphism (SNP) markers, Genome-Wide Association Studies (GWAS), and Genomic Selection (GS). Integrating SSR-based approaches with modern genomic tools offers a promising strategy for developing climate-resilient tomato cultivars and enhancing future food security.

This study examines the effects of Net Profit Margin, audit opinion, and firm size on audit delay among construction companies listed on the Indonesia Stock Exchange from 2019 to 2025. Audit delay is measured as the period between the fiscal year-end and the issuance date of the independent auditor’s report. Timely financial reporting is particularly important in the construction sector due to its complex long-term projects, progress-based revenue recognition, cost estimation, and high financial risks. Using a quantitative approach, the study analyzes secondary data from annual financial statements and independent auditor reports. The sample includes 14 construction companies observed over seven years, producing 98 observations. Panel data regression was conducted using EViews, with the Chow, Hausman, and Lagrange Multiplier tests identifying the Random Effect Model as the most appropriate estimation method. The findings show that Net Profit Margin does not significantly affect audit delay. In contrast, audit opinion and firm size have negative and significant effects, indicating that favorable audit opinions and larger company size are associated with shorter audit completion periods. Collectively, the three variables significantly influence audit delay, although they explain only 15.75% of its variation.

Partographs are an important instrument in labor monitoring that functions to detect complications early, monitor labor progress, and support appropriate clinical decision-making. However, incomplete filling of partographs is still a problem in various health service facilities and has the potential to affect the quality of midwifery services. This study aims to find out the completeness of filling in the partograph in childbirth monitoring at the Wajo Health Center UPTD Baubau City. This study uses a quantitative method with a descriptive design. The research population is all partograph documents for the period November 2025 to March 2026 as many as 40 documents. The sampling technique used total sampling and obtained 32 documents that met the research criteria. Data were collected using an observation checklist sheet and analyzed univariately through frequency and percentage distributions. The results showed that as many as 28 documents (87.5%) had not been fully filled out and only 4 documents (12.5%) had been filled in completely. The components with the highest level of completeness were uterine contractions (100%), drugs and fluids (96.9%), and labor progress (93.8%). Meanwhile, the components of maternal information (12.5%) and maternal condition (31.3%) had the lowest level of completeness. Most of the filling of partographs at the Wajo Health Center UPTD still does not meet the completeness standards. It is necessary to strengthen supervision, training, and periodic monitoring to improve the quality of childbirth documentation and support the safety of mothers and babies

This study examines Income Tax provisions under the latest tax regulations in Indonesia, explains the procedures and mechanisms for calculating Income Tax based on the Law on Harmonization of Tax Regulations (HPP Law), and evaluates the contribution of Income Tax to state revenue and equitable income distribution. This research applies library research with a qualitative descriptive approach. The data were collected from relevant sources, including laws and regulations, academic books, scientific articles, research journals, and official government publications related to Income Tax policy in Indonesia. The data were analyzed systematically to identify regulatory developments, tax calculation mechanisms, and the implications of tax policy for national state revenue and fiscal justice. The findings show that the HPP Law establishes five progressive tariff layers for Individual Taxpayers, with a maximum rate of 35% imposed on taxable income exceeding IDR 5 billion per year. This provision reflects the principles of ability to pay and vertical equity in Indonesia’s tax system. Furthermore, the Corporate Income Tax rate of 22%, along with various rate-reduction incentives for eligible taxpayers, can enhance business competitiveness and reduce tax burdens. Tax administration modernization through e-Filing, e-Billing, e-Bupot, and Coretax also improves service efficiency and strengthens taxpayer compliance more effectively.

This study looks at how da'wah management plays a role in running the Qur'an memorization curriculum at SDIT Islamiyah Proyek Desa Belinteng. The tahfizh program isn't just seen as a way to pass on religious knowledge it's also viewed as a da'wah tool and a means of building religious character in students from an early age. The study aims to explore how management functions including planning, organizing, directing, and evaluating are applied in running the tahfizh program at the school. The research uses a descriptive qualitative approach, with data collected through interviews, observation, and document review. The key informants were the school principal and the tahfizh teachers. The findings show that the tahfizh program has been managed in a fairly structured way, covering memorization target-setting, clear division of responsibilities, regular memorization sessions, and periodic progress assessments. Beyond improving students' memorization skills, the program also helps instill discipline, good manners, and a love for the Qur'an. That said, the program still faces some challenges, mainly students' lack of focus and limited muroja'ah practice at home.

This study is motivated by the proliferation of regulations that facilitate the exploitative extraction of natural resources in Indonesia as a consequence of the penetration of neoliberal ideology, which deviates from the mandate of Article 33 of the 1945 Constitution of the Republic of Indonesia. The significance of this research lies in the strategic role of Muhammadiyah through the "Constitutional Jihad" movement in restoring state sovereignty over natural resources for the benefit of the public welfare. The study aims to analyze the philosophical foundations of Constitutional Jihad in reconstructing the vision of a Progressive Indonesia (Indonesia Berkemajuan) and to examine Muhammadiyah’s legal advocacy strategies in resisting the hegemony of liberal economic policies. The research focuses on how Muhammadiyah’s philosophical framework and litigation strategies are capable of correcting national energy policies, as reflected in Constitutional Court Decision Number 36/PUU-X/2012. This research employs a normative legal method using statutory, case, and theological-ideological approaches. The findings reveal that, philosophically, Constitutional Jihad represents the transformation of Al-Ma’un theology and the concept of Darul Ahdi wa Syahadah into a constitutional framework that integrates divine sovereignty with popular sovereignty. In terms of strategy, Muhammadiyah utilizes Public Interest Litigation supported by interdisciplinary expert collaboration and moral mobilization rooted in civil society. The analysis of Constitutional Court Decision No. 36/PUU-X/2012 demonstrates that Muhammadiyah’s advocacy successfully invalidated unconstitutional provisions of the Oil and Gas Law that had weakened state control, while simultaneously reaffirming the state's direct management function over natural resources. The study concludes that Constitutional Jihad constitutes an effective form of national ijtihad in reconstructing a progressive, sovereign, and socially just legal order in Indonesia.

The governance of sand and gravel mining requires an integrated assessment of technical planning, occupational safety, environmental control, reclamation, and regulatory compliance. This study evaluated the governance of CV. Ria Bersaudara, a sand and gravel mining company located in Pasar Surulangun, Rawas Ulu District, Musi Rawas Utara Regency, using the Good Mining Practice framework. The study used a descriptive evaluative approach based on field observation, document review, indicative resource estimation, equipment productivity analysis, occupational safety and environmental risk assessment, and compliance mapping. The results show that the company has a basic legal foundation through an exploration mining permit covering 12.5 ha; however, several governance components require improvement. The indicative prospective area was approximately 2.50 ha, with an effective follow-up area of 1.80 ha and an estimated indicative resource of 21,600 m³ or 35,640 tons. Productivity analysis indicated that excavator capacity reached about 61 m³/hour, while one dump truck only transported about 10.3 m³/hour, creating a haulage bottleneck if the truck fleet is insufficient. Safety implementation was also not optimal, with personal protective equipment compliance estimated at only 55%. The study recommends validating permit documents, strengthening technical exploration data, improving drainage and sediment control, enforcing safety procedures, implementing progressive reclamation, and establishing daily operational records.

Road improvement projects require consistency between technical planning documents and field implementation to ensure that service quality, structural performance, construction time, and user safety are achieved. This article evaluates the conformity between planning and realization in the Pangkalan-Batas Jambi road improvement project in Rawas Ulu District, North Musi Rawas Regency. The study used a descriptive-quantitative evaluative approach based on field monitoring, project technical documents, comparative quantity analysis between contract and Contract Change Order (CCO), and identification of implementation constraints. The results showed that several work items changed during construction because initial planning data did not fully capture actual field conditions. Quantities increased for drainage excavation (+18.87%), roadbed preparation (+8.99%), aggregate class A base course (+12.51%), and AC-Base (+11.98%). Conversely, reinforced pipe culverts decreased (-58.33%), unsealed aggregate base/sirtu decreased (-43.50%), and tack/prime coat volume slightly decreased (-0.47%). The time schedule showed a minor delay of -0.13% in the first week but recovered in the second week, indicating effective field coordination. Main constraints included traffic interference, limited worker visibility, and equipment visibility. The study recommends more detailed site surveys during planning, stronger traffic management, stricter occupational safety implementation, systematic progress control, and routine post-construction maintenance to maintain road service life.

Education plays a fundamental role in shaping the quality of human resources and determining national progress. However, many young people still lack awareness and motivation regarding the importance of education due to limited access to information, socioeconomic challenges, and insufficient understanding of its long-term benefits. This Community Service Program aims to increase young people’s awareness of the importance of education through collaboration among multiple universities. The program involved lecturers and students from various higher education institutions who conducted educational outreach activities, motivational seminars, interactive discussions, and mentoring sessions. Methods used included educational counseling, inspirational presentations, question-and-answer sessions, and participant evaluations. The results show an improvement in participants’ understanding, motivation, and awareness of education as an investment in the future. In addition, inter-university collaboration expanded the program’s reach, enriched perspectives shared with participants, and strengthened higher education institutions’ commitment to community engagement. This initiative demonstrates that cross-university synergy can serve as an effective and sustainable model for fostering educational awareness and supporting the development of future generations in diverse communities.

This study examines the gap between Nestlé’s sustainability commitments and the reality of ecological damage caused by the use of unsustainable raw materials in its global supply chain. Using a descriptive qualitative approach based on literature reviews and case study analysis, this study evaluates various data sources, ranging from scientific journals and corporate reports to documentation from independent organizations such as Greenpeace and the Rainforest Action Network. Findings indicate that Nestlé’s procurement of key commodities such as palm oil, cocoa, soy, dairy products, and singleuse plastics significantly contributes to deforestation, systemic plastic pollution, water extraction in vulnerable regions, and greenhouse gas emissions exceeding 87.5 million tons of CO₂e per year. In Indonesia, these highrisk areas are evident in palm oil sourcing in Sumatra and Kalimantan and cocoa sourcing in Sulawesi. Theoretically, this study argues that Nestlé’s sustainability governance exhibits a pattern of strategic decoupling, where public reporting on progress in primary supply chains is deliberately used to mask ongoing environmental damage within their hidden supply networks. Thus, this article makes a critical contribution by integrating supply chain management theory, environmental accountability, and the governance of multinational corporations.

Background: The elderly are a vulnerable group requiring special attention, particularly regarding degenerative diseases like hypertension. In Melinggih Village, there are around 250 elderly residents, but participation in village activities is very low (only 57 are active). The main issues include limited information on degenerative diseases, a lack of skills in preparing traditional medicine, and weak cadre capacity in designing productive activities. Based on these conditions, this community service program (PKM) was implemented to improve the quality of life, health, independence, and productivity of the elderly, supporting the Indonesia Emas 2045 Vision and SDGs targets. Method: The research team partnered with the elderly group. Implemented solutions included education on degenerative diseases, training in making celery-based herbal drinks using Balinese local wisdom to lower hypertension, cadre mentoring, and elderly gymnastics. The program concluded with a comprehensive evaluation of participants' knowledge and skills. Results: Active activities were structured to increase elderly productivity: 1) Elderly gymnastics, educational activities, and active mentoring were conducted with the PKM team, cadres, and elderly in Melinggih Village regarding hypertension, resulting in increased knowledge and skills in managing elderly hypertension. 2) The elderly learned to make herbal drinks from celery. 3) Health cadres appeared active and collaborated well with the PKM team. Conclusion: Education on degenerative diseases, specifically hypertension, went well, successfully increasing cadres' and the elderly's understanding of their conditions to optimize health awareness. Training on traditional medicine preparation, specifically making celery drinks to lower hypertension, also progressed successfully.

Background: Labor is a physiological process that is commonly accompanied by pain, causing discomfort, anxiety, and fear that may interfere with maternal well-being and labor progress. Effleurage massage is a complementary, non-pharmacological intervention used to reduce labor pain. Purpose: This study aimed to evaluate the effectiveness of effleurage massage in reducing pain intensity during the first stage of labor. Method: A literature review was conducted using articles retrieved from Google Scholar. An initial search identified 45 articles, and after screening based on publication year (2021–2026), relevance, and inclusion criteria, 10 research articles were included for analysis. Data were extracted and synthesized descriptively. Results: The findings consistently showed that effleurage massage reduced labor pain by promoting relaxation, decreasing muscle tension, improving blood circulation, and stimulating endorphin release through the gate control mechanism. Most studies also reported improved maternal comfort during labor. Conclusion: In conclusion, effleurage massage is an effective, safe, affordable, and easy-to-apply complementary therapy that can be integrated into midwifery care to reduce labor pain and enhance maternal comfort.  

This study aims to describe the management of the Tahfidz Al-Qur'an Program, identify the supporting and inhibiting factors in its implementation, and analyze its contribution to improving educational quality at SD Qurrota 'Ayun Kalibeber Wonosobo. A qualitative approach with a field research design was employed. Data were collected through observations, interviews, and documentation involving the principal, tahfidz coordinator, tahfidz teachers, classroom teachers, students, and parents. Data were analyzed using the Miles and Huberman model, including data reduction, data display, and conclusion drawing. The findings show that the Tahfidz Al-Qur'an Program has been systematically managed through the functions of planning, organizing, actuating, and controlling. Planning includes determining memorization targets, preparing the curriculum, scheduling activities, selecting learning methods, assigning qualified teachers, and establishing evaluation procedures. Organizing involves a clear distribution of responsibilities among school stakeholders and parents. Program implementation consists of tahsin, memorization submission, muraja'ah, and periodic evaluations, while monitoring is conducted through memorization assessments, evaluation meetings, and progress reports to parents. Supporting factors include the principal’s commitment, competent tahfidz teachers, parental involvement, and a religious school environment. Inhibiting factors include differences in students’ abilities, limited muraja'ah at home, time constraints, and fluctuating learning motivation. The program contributes to educational quality by strengthening religious character, improving academic achievement, fostering school discipline, and increasing public trust in the institution.

Dysphagia in extremely elderly patients represents a significant clinical challenge because it is frequently associated with frailty, malnutrition, and an increased risk of aspiration. Multifactorial etiologies and atypical clinical manifestations may complicate diagnosis and delay appropriate management. This study aimed to describe the diagnostic evaluation and clinical findings of dysphagia in an extremely elderly patient through a case report supported by a scoping review. A 105-year-old woman with chronic progressive dysphagia underwent comprehensive assessment, including physical examination, upper gastrointestinal endoscopy, histopathological evaluation, and chest radiography. Relevant literature on dysphagia in geriatric populations was reviewed to provide contextual understanding of diagnostic challenges and underlying etiologies. The evaluation revealed chronic active gastritis and a hamartomatous polyp in the gastroesophageal region without evidence of malignancy. Comprehensive assessment successfully excluded malignant and acute obstructive causes, emphasizing the complexity of dysphagia diagnosis in extremely elderly individuals with frailty and aspiration risk. These findings underscore the importance of endoscopic and histopathological examinations in distinguishing benign from malignant etiologies and support early recognition of multifactorial non-malignant causes to optimize clinical management and reduce the risk of adverse outcomes in this vulnerable population

Project scheduling is a critical aspect of ensuring the successful implementation of construction projects, particularly bridge projects that involve a high degree of complexity. Poor schedule quality may result in project delays, inaccurate critical path identification, and inadequate project control. This study aims to evaluate the schedule quality of a pile slab bridge project using the Defense Contract Management Agency (DCMA) 14-Point Schedule Assessment method, supported by Oracle Primavera P6 software. The study employed a quantitative descriptive method with a case study approach applied to an existing baseline schedule. The assessment results indicate that several parameters have satisfied the DCMA standards, including relationship type, hard constraints, soft constraints, negative float, large duration, and invalid progress. Conversely, several parameters remain non-compliant with the established standards, namely network logic, positive lag, large float, resources/cost, and the Baseline Execution Index (BEI). This study concludes that the project schedule has not fully adhered to the principles of a network-driven schedule and continues to function primarily as an administrative time schedule. The findings of this study offer practical contributions to construction project management by providing recommendations that encompass the refinement of network logic relationships, reduction of excessive lag usage, implementation of resource and cost loading, and progress updates based on the established baseline, thereby enabling the schedule to serve as a more effective, reliable, and integrated project control tool

Muscle-invasive bladder cancer (MIBC) is an aggressive malignancy associated with high morbidity, reduced survival, and impaired quality of life. Radiotherapy (RT) has been widely used as a bladder-preserving strategy, particularly for patients unsuitable for surgery or systemic chemotherapy. RT may also enhance tumor immunogenicity through programmed death-ligand 1 (PD-L1) upregulation, providing a rationale for combination therapy with immunotherapy. This study aimed to evaluate the effectiveness of combining immunotherapy and radiotherapy in MIBC treatment. A systematic review was conducted following PRISMA 2020 guidelines using the PICO framework. Literature searches were performed in PubMed, Embase, Cochrane, ClinicalTrials.gov, Web of Science, and Scopus databases for studies published between 2016 and 2025. Risk of bias was assessed using the Cochrane Risk of Bias Tool and ROBINS-I. Of 105 identified studies, five met the inclusion criteria and were included in the final analysis. Only one Phase II randomized controlled trial demonstrated low risk of bias in randomization and allocation concealment. ROBINS-I assessment indicated moderate to serious risk in confounding and participant selection domains. Clinical findings showed promising outcomes, with complete response rates ranging from 35%–50% and partial response rates from 25%–40%. Median overall survival ranged from 24–30 months, with favorable disease-free and progression-free survival outcomes. Combined immunotherapy and radiotherapy demonstrate potential to improve survival and disease control in MIBC; however, further rigorous clinical studies are needed to optimize patient-centered treatment strategies.  

The imbalance in bargaining position between business actors and consumers frequently places consumers in a vulnerable position to economic exploitation through the inclusion of standard clauses and unfair trade practices. This study aims to analyze the fulfillment of rights and obligations of the parties, identify the comprehensive boundaries of prohibited acts for business actors, and examine the legal binding force of standard clauses in commercial transactions under Law Number 8 of 1999 concerning Consumer Protection (UUPK). The method employed in this research is a normative juridical legal approach with statutory and conceptual analysis, utilizing qualitative analysis of secondary data obtained from library research combined with a deductive reasoning method. The findings underscore two pivotal aspects. First, the weak standing of consumers in the market is driven not only by economic imbalances but also by low legal awareness and minimal information transparency regarding quality standardization. Second, the inclusion of standard clauses that unilaterally transfer liability (exculpatory clauses) is strictly prohibited by Article 18 of UUPK and declared null and void, which aligns with the progressive judicial stance in the landmark Supreme Court Civil Judicial Review Decision Number 124/PK/PDT/2007. The theoretical implication of this study urges a reconstruction of the freedom of contract doctrine bounded by distributive justice, while its practical implication recommends the government, YLKI, and BPKN to tighten preventive oversight through auditing draft standard agreements in public spaces and formulating adaptive regulations toward digital contract disruptions.

This study investigates the development of Indonesian language literacy among third-grade elementary school students. The primary problems identified were acute classroom passivity and low reading comprehension, evidenced by an initial learning mastery of only 45.16%, which were largely driven by conventional teacher-centered pedagogy. The objective of this research is to enhance early-grade reading literacy and active participation through an innovative instructional intervention. The proposed method employed a two-cycle Classroom Action Research (CAR) design at SDN Jrebeng Kulon 1, integrating the Problem-Based Learning (PBL) model assisted by serial picture media. This approach utilizes chronological visual scaffolding to facilitate narrative comprehension for students in the concrete operational stage. The results demonstrated a highly significant academic progression: classical learning mastery increased to 70.97% (mean score: 80.80) in Cycle I and culminated in an absolute 100% mastery rate (mean score: 94.51) by the end of Cycle II. The synthesis of these findings reveals that transitioning from static visual aids to serial visual stimuli within a problem-oriented framework effectively mitigates cognitive dissonance and eradicates classroom passivity. In conclusion, the integration of the PBL model with serial picture media serves as a comprehensive pedagogical solution that not only maximizes cognitive reading comprehension but also reconstructs students' verbal articulation and social-collaborative skills, offering a highly scalable strategy for early primary education.

Allergic rhinitis (AR) is a chronic inflammatory disorder of the nasal mucosa mediated by immunoglobulin E (IgE) in response to allergen exposure. This condition has become a significant global health concern because of its increasing prevalence and substantial impact on quality of life, sleep, cognitive function, and work productivity. AR is also commonly associated with other atopic diseases, including asthma and atopic dermatitis. This article aims to review the current understanding of allergic rhinitis, focusing on epidemiology, pathophysiology, clinical manifestations, diagnostic approaches, and evidence-based management strategies. This study used a narrative literature review method by analyzing scientific articles, clinical guidelines, and peer-reviewed journals published between 2015 and 2025. Literature sources were obtained from PubMed, Google Scholar, and relevant medical databases using keywords related to allergic rhinitis, IgE, diagnosis, and immunotherapy. The findings indicate that allergic rhinitis involves complex immune mechanisms characterized by Th2 lymphocyte activation, IgE production, and inflammatory mediator release. Diagnosis is primarily established clinically and supported by allergy testing such as skin prick tests or serum-specific IgE measurement. Intranasal corticosteroids remain the first-line therapy for moderate to severe cases, while antihistamines and leukotriene receptor antagonists are used as adjunctive therapies. Allergen immunotherapy has shown effectiveness in modifying disease progression and improving long-term outcomes. In conclusion, allergic rhinitis is a manageable chronic disease that requires a comprehensive and individualized treatment approach involving environmental control, pharmacotherapy, and immunotherapy.

Construction project control requires careful planning to avoid delays and cost overruns. This study aims to evaluate the performance of the CBT Laboratory Building construction project at the Faculty of Medicine, Wahid Hasyim University, Semarang, in terms of cost and time using the Earned Value Analysis (EVA) method, and to analyze acceleration alternatives using the crashing method. The method used is a quantitative approach with a case study, based on project data such as the Budget Plan (RAB), S-curve, and work progress reports. The analysis was carried out using the Earned Value Analysis (EVA) method to assess project performance in terms of cost and time through indicators such as CV, SV, CPI, and SPI. Furthermore, an acceleration analysis was conducted using the crashing method to determine the optimal alternative for overcoming project delays by considering time and cost efficiency. The results of the Earned Value Analysis indicate that the project experienced delays and cost overruns, as shown by SPI < 1 and CPI < 1. The estimated project completion time increased to 227 days, longer than the initial plan of 217 days, while the estimated final cost reached RP 5,451,241,064.85, exceeding the initial budget. Acceleration efforts using the crashing method show that adding adding labor is more efficient than working hours (overtime), resulting in a project duration of 212 days with lower costs of RP 5,658,221,364.08. Thus, the Earned Value Analysis method is effective for evaluating project performance, while crashing can be a solution for acceleration by considering time and cost efficiency.