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Drug abuse among university students is a problem that needs serious attention because it can damage health, reduce academic achievement, and hinder the future of the younger generation. University students are in a phase of self-discovery, making them susceptible to unhealthy environments and social circles. Therefore, comprehensive drug prevention efforts are needed in higher education settings. This article discusses various forms of drug prevention among students through education, character building, and active student involvement in positive activities. The method used is a literature review from various relevant sources. The results of the discussion show that drug prevention can be effective if supported by cooperation between the campus, families, and students. Education about the dangers of drugs, strengthening moral values, and creating a safe and healthy campus environment are important steps in preventing drug abuse. With continuous prevention efforts, it is hoped that students will be able to protect themselves from the influence of drugs and play a role as a healthy, accomplished, and responsible young generation.