Phytochemical Constituents and Pharmacological Potential of Justicia gendarussa Burm. f.: A Review

Annisa Nofriani ; Naura Nurnahari
Jurnal Ilmu Kesehatan 📅 2025 Vol 2, No 2 🔗 DOI: 10.62383/quwell.v2i2.2283
Abstract
Justicia gendarussa Burm. f., commonly known as gandarusa, is a medicinal shrub widely distributed in South and Southeast Asia. Traditionally, it has been used for treating rheumatism, headache, asthma, bronchitis, skin infections, and as a male contraceptive. Phytochemical analyses revealed the presence of alkaloids (gendarusin A, gendarusin B), flavonoids (quercetin, kaempferol, apigenin), saponins, tannins, phenolics, terpenoids, and Patentiflorin A, a compound with promising anti-HIV activity. Pharmacological investigations demonstrated its anti-inflammatory, analgesic, antimicrobial, antioxidant, antidiabetic, hepatoprotective, immunomodulatory, anticancer, and contraceptive potentials. This review highlights the phytochemical profile, pharmacological properties, and future prospects of J. gendarussa, emphasizing its potential as a phytopharmaceutical candidate. Further studies are required to standardize extracts, confirm clinical efficacy, and ensure long-term safety.
Keywords
Justicia Gendarussa; Male Contraceptive; Patentiflorin A; Pharmacology; Phytochemistry
How to Cite

Annisa Nofriani & Naura Nurnahari (2025). Phytochemical Constituents and Pharmacological Potential of Justicia gendarussa Burm. f.: A Review. Jurnal Ilmu Kesehatan, 2(2). https://doi.org/10.62383/quwell.v2i2.2283

Annisa Nofriani; Naura Nurnahari, "Phytochemical Constituents and Pharmacological Potential of Justicia gendarussa Burm. f.: A Review," Jurnal Ilmu Kesehatan, vol. 2, no. 2, 2025.

Annisa Nofriani; Naura Nurnahari. "Phytochemical Constituents and Pharmacological Potential of Justicia gendarussa Burm. f.: A Review." Jurnal Ilmu Kesehatan, vol. 2, no. 2, 2025.

Annisa Nofriani; Naura Nurnahari. "Phytochemical Constituents and Pharmacological Potential of Justicia gendarussa Burm. f.: A Review." Jurnal Ilmu Kesehatan 2, no. 2 (2025).

Annisa Nofriani & Naura Nurnahari (2025) 'Phytochemical Constituents and Pharmacological Potential of Justicia gendarussa Burm. f.: A Review', Jurnal Ilmu Kesehatan, 2(2). doi: 10.62383/quwell.v2i2.2283.

Annisa Nofriani; Naura Nurnahari. Phytochemical Constituents and Pharmacological Potential of Justicia gendarussa Burm. f.: A Review. Jurnal Ilmu Kesehatan. 2025;2(2).

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