Dehydroepiandrosterone Sulfate Deficiencies as Independent Predictors of Increased Coronary Artery Disease in Men with Type II Diabetes Mellitus

Mustafa A-Jabbar Al-Jumaili ; Abdullah Ali Mohammed ; Hawraa M. Alaa Alden ; Sura A. Abdulsattar
Jurnal Riset Ilmu Farmasi dan Kesehatan 📅 2025 Vol 3, No 1 🔗 DOI: 10.61132/obat.v3i1.984
Abstract
The adrenal cortex synthesis the steroid hormone dehydroepiandrosterone (DHEA), has a significant effect on diabetes mellitus. Our study targeted to estimate the relationship between serum levels of DHEA sulphate (DHEAS) and the risk of CAD complication for T2DM in men. Ninety Iraqi male subjects were divided into three groups. Each group has thirty people: thirty people type 2 with diabetes mellitus, thirty person type 2 diabetes mellitus patients with CAD complications, and the control group has thirty healthy people. A significant decrease (p<0.01) of DHEAS, was observed in T2DM with CAD (120.8 µg/dl) compared to both T2DM (141.26 µg/dl) and the control group (239.86 µg/dl). Meanwhile, an increased coronary risk index in T2DM with CAD (10.68) compared to both T2DM (7.56) and control group (4.41) was observed. These findings were confirmed by the negative correlation of DHEAs with coronary risk index. We suggested that a decreased level of DHEAS value may be a beneficial sign for future CAD in patients with T2DM.
Keywords
Diabetes ; Dehydroepiandrosterone Sulfate; Insulin; Lipid; Complication
How to Cite

Mustafa A-Jabbar Al-Jumaili, et al. (2025). Dehydroepiandrosterone Sulfate Deficiencies as Independent Predictors of Increased Coronary Artery Disease in Men with Type II Diabetes Mellitus. Jurnal Riset Ilmu Farmasi dan Kesehatan, 3(1). https://doi.org/10.61132/obat.v3i1.984

Mustafa A-Jabbar Al-Jumaili; Abdullah Ali Mohammed; Hawraa M. Alaa Alden; Sura A. Abdulsattar, "Dehydroepiandrosterone Sulfate Deficiencies as Independent Predictors of Increased Coronary Artery Disease in Men with Type II Diabetes Mellitus," Jurnal Riset Ilmu Farmasi dan Kesehatan, vol. 3, no. 1, 2025.

Mustafa A-Jabbar Al-Jumaili; Abdullah Ali Mohammed; Hawraa M. Alaa Alden; Sura A. Abdulsattar. "Dehydroepiandrosterone Sulfate Deficiencies as Independent Predictors of Increased Coronary Artery Disease in Men with Type II Diabetes Mellitus." Jurnal Riset Ilmu Farmasi dan Kesehatan, vol. 3, no. 1, 2025.

Mustafa A-Jabbar Al-Jumaili; Abdullah Ali Mohammed; Hawraa M. Alaa Alden; Sura A. Abdulsattar. "Dehydroepiandrosterone Sulfate Deficiencies as Independent Predictors of Increased Coronary Artery Disease in Men with Type II Diabetes Mellitus." Jurnal Riset Ilmu Farmasi dan Kesehatan 3, no. 1 (2025).

Mustafa A-Jabbar Al-Jumaili, et al. (2025) 'Dehydroepiandrosterone Sulfate Deficiencies as Independent Predictors of Increased Coronary Artery Disease in Men with Type II Diabetes Mellitus', Jurnal Riset Ilmu Farmasi dan Kesehatan, 3(1). doi: 10.61132/obat.v3i1.984.

Mustafa A-Jabbar Al-Jumaili; Abdullah Ali Mohammed; Hawraa M. Alaa Alden; Sura A. Abdulsattar. Dehydroepiandrosterone Sulfate Deficiencies as Independent Predictors of Increased Coronary Artery Disease in Men with Type II Diabetes Mellitus. Jurnal Riset Ilmu Farmasi dan Kesehatan. 2025;3(1).

Artikel Terkait

Pola Penggunaan Antibiotik dan Resistensi Bakteri di Rumah Sakit: Literature Review

Iin Riana; Khofifah Ali Safitri; Mey Apriansyah

Gen Z Sehat Kenali Bahaya Vape, Seks Bebas, Penyalahgunaan Obat di SMA Negeri 3 Lamongan

Djati Wulan Khusumo; Situmeang, Andre; Aprilia Suryan Dini; Eka Wulan Ndari; Lifriana Zahwa Nabila

Tingkat Ketersediaan Obat di Puskesmas Kota Selatan dan Puskesmas Piloloda’a Tahun 2024

Muhammad Ridho Jasin; Madania Madania; Teti Sutriyati Tuloli

Literature Review: Baby Massage Sebagai Terapi Komplementer Diare pada Balita

Diah Karina Wibowo; Ervina Damayanti; Ramadhan Triyandi; Muhammad Fitra Wardhana Sayoeti

Evaluasi Peresepan Obat Berdasarkan Indikator Peresepan WHO di Apotek M Bandung

Saviola Saviola; Keri Lestari

Analisis Faktor Risiko Kontaminasi Entamoeba histolytica pada Air Sumur Masyarakat di Desa Paya Leupah, Kecamatan Simpang Keramat, Aceh Utara

Tita Aulia Putri; Rizka Sofia; Mohammad Mimbar Topik
Tren Sitasi Jurnal