Modification of Gemifloxacin Drug Antibacterial to Promising Anti-Prostate Cancer PC3 Azomethine Compounds: Synthesis and in Vitro Studies

Rand Thair Abdulkader ; Reyam H. Marah ; Aqeel Mohamed ; Abbas K. Abbas
Jurnal Riset Ilmu Farmasi dan Kesehatan 📅 2024 Vol 2, No 5 🔗 DOI: 10.61132/obat.v2i5.665
Abstract
In this study, we report a novel azomethine derivatives synthesis (H and G) by reacting pure Gemifloxacin drugs with 2-aminobenzaldehyde and 2-methylbenzaldehyde. Spectroscopic techniques, such as FT‐IR spectroscopy, characterized the derivatives (G and H). All the synthesized derivatives (G and H) were evaluated in vitro against microorganisms such as Bacillus subtilis and E. coli by zone inhibition method and screened for antimicrobial activities and anti-Prostate cancer PC3 cell viability cell lines.
Keywords
Antibacterial; Antibiotic; Gemifloxacin; Cancer
How to Cite

Rand Thair Abdulkader, et al. (2024). Modification of Gemifloxacin Drug Antibacterial to Promising Anti-Prostate Cancer PC3 Azomethine Compounds: Synthesis and in Vitro Studies. Jurnal Riset Ilmu Farmasi dan Kesehatan, 2(5). https://doi.org/10.61132/obat.v2i5.665

Rand Thair Abdulkader; Reyam H. Marah; Aqeel Mohamed; Abbas K. Abbas, "Modification of Gemifloxacin Drug Antibacterial to Promising Anti-Prostate Cancer PC3 Azomethine Compounds: Synthesis and in Vitro Studies," Jurnal Riset Ilmu Farmasi dan Kesehatan, vol. 2, no. 5, 2024.

Rand Thair Abdulkader; Reyam H. Marah; Aqeel Mohamed; Abbas K. Abbas. "Modification of Gemifloxacin Drug Antibacterial to Promising Anti-Prostate Cancer PC3 Azomethine Compounds: Synthesis and in Vitro Studies." Jurnal Riset Ilmu Farmasi dan Kesehatan, vol. 2, no. 5, 2024.

Rand Thair Abdulkader; Reyam H. Marah; Aqeel Mohamed; Abbas K. Abbas. "Modification of Gemifloxacin Drug Antibacterial to Promising Anti-Prostate Cancer PC3 Azomethine Compounds: Synthesis and in Vitro Studies." Jurnal Riset Ilmu Farmasi dan Kesehatan 2, no. 5 (2024).

Rand Thair Abdulkader, et al. (2024) 'Modification of Gemifloxacin Drug Antibacterial to Promising Anti-Prostate Cancer PC3 Azomethine Compounds: Synthesis and in Vitro Studies', Jurnal Riset Ilmu Farmasi dan Kesehatan, 2(5). doi: 10.61132/obat.v2i5.665.

Rand Thair Abdulkader; Reyam H. Marah; Aqeel Mohamed; Abbas K. Abbas. Modification of Gemifloxacin Drug Antibacterial to Promising Anti-Prostate Cancer PC3 Azomethine Compounds: Synthesis and in Vitro Studies. Jurnal Riset Ilmu Farmasi dan Kesehatan. 2024;2(5).

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