Efek Kava (Piper Methysticum) Sebagai Anestesi

Lasmaria Flora Roslinda Silaen ; Matdhika Sakti ; Ferianto Ferianto
Jurnal Ventilator: Jurnal riset ilmu kesehatan dan... 📅 2025 Vol 3, No 1 🔗 DOI: 10.59680/ventilator.v3i1.1737
Abstract
Kava (Piper Methysticum) is a plant traditionally used in the South Pacific for its sedative and anxiolytic effects. Its active compounds, kavalactones, are known to have potential as natural anesthetics, with a mechanism of action similar to benzodiazepines and general anesthetics. This study aims to evaluate the effectiveness of Kava as an anesthetic through a systematic literature review and meta-analysis. Literature searches were conducted in PubMed, Scopus, and Cochrane Library using relevant keywords. Meta-analysis results indicate that Kava significantly enhances anesthetic effects compared to placebo, primarily through modulation of GABA-A receptors. However, further research is needed to determine the optimal dosage and long-term safety.
Keywords
Kava; Piper methysticum; Anesthesia; Kavalactones; Central nervous system; Systematic review; Meta-analysis
How to Cite

Lasmaria Flora Roslinda Silaen, et al. (2025). Efek Kava (Piper Methysticum) Sebagai Anestesi. Jurnal Ventilator: Jurnal riset ilmu kesehatan dan Keperawatan, 3(1). https://doi.org/10.59680/ventilator.v3i1.1737

Lasmaria Flora Roslinda Silaen; Matdhika Sakti; Ferianto Ferianto, "Efek Kava (Piper Methysticum) Sebagai Anestesi," Jurnal Ventilator: Jurnal riset ilmu kesehatan dan Keperawatan, vol. 3, no. 1, 2025.

Lasmaria Flora Roslinda Silaen; Matdhika Sakti; Ferianto Ferianto. "Efek Kava (Piper Methysticum) Sebagai Anestesi." Jurnal Ventilator: Jurnal riset ilmu kesehatan dan Keperawatan, vol. 3, no. 1, 2025.

Lasmaria Flora Roslinda Silaen; Matdhika Sakti; Ferianto Ferianto. "Efek Kava (Piper Methysticum) Sebagai Anestesi." Jurnal Ventilator: Jurnal riset ilmu kesehatan dan Keperawatan 3, no. 1 (2025).

Lasmaria Flora Roslinda Silaen, et al. (2025) 'Efek Kava (Piper Methysticum) Sebagai Anestesi', Jurnal Ventilator: Jurnal riset ilmu kesehatan dan Keperawatan, 3(1). doi: 10.59680/ventilator.v3i1.1737.

Lasmaria Flora Roslinda Silaen; Matdhika Sakti; Ferianto Ferianto. Efek Kava (Piper Methysticum) Sebagai Anestesi. Jurnal Ventilator: Jurnal riset ilmu kesehatan dan Keperawatan. 2025;3(1).

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