Case Study: The Investigation of Drug Induced Liver Injury: A Case Study in In- patient of Internal Medicine Ward

Risalati ; PN ; Alfarizi ; Gilang Rizki ; Lusia ; P ; Aurelia ; RP
The International Conference on Health Practice an... 📅 2022 Vol 3
Abstract
Adverse Drug Reactions (ADR's) caused by the use of drugs are still often founded in health services, especially those with the potential for Drug Induce Liver Injury. Therefore we need a measurement instrument to identify these events to prevent the hepatotoxic effects. In this case study, it was reported that a 22-year-old patient was admitted to a Surabaya city hospital in September 6, 2017 with complaints of nausea, vomiting, fever and decreased of appetite. On the laboratory examination found an increase in the total bilirubin value and Gamma Glutamyl Transferase. ALT significantly increased > 3x and ALP > 2x from the normal value. Based on the results of ultrasound and MRI, the impression of Gall Bladder Contracted and Cholecystitis Suspected were obtained with the conclusion that there was no obstruction of the biliary system and the normal abdominal organs. From the results of an in-depth investigation, the patient said that he regularly consumes Carrol Superpil to reduce back pain. After the clinical pharmacy assessment for the first Patient was DILI with a RUCAM score of 7 (probable DILI) due to the use of Carrol Superpil as well as the presence of Drug Related Problems in the patient, namely as Ceftriaxone which prescribed during the hospitalization which could affect ALT/ALP, it is recommended to replace antibiotics with Cefotaxime 3x1 gr.
Keywords
Adverse Drug Reaction; Drug Induce Liver Injury; Drug Related Problems; Roussal Uclaf Causality Assessment Method
How to Cite

Risalati, et al. (2022). Case Study: The Investigation of Drug Induced Liver Injury: A Case Study in In- patient of Internal Medicine Ward . The International Conference on Health Practice and Research (ICHPR), 3.

Risalati, PN; Alfarizi, Gilang Rizki; Lusia, P; Aurelia, RP, "Case Study: The Investigation of Drug Induced Liver Injury: A Case Study in In- patient of Internal Medicine Ward ," The International Conference on Health Practice and Research (ICHPR), vol. 3, 2022.

Risalati, PN; Alfarizi, Gilang Rizki; Lusia, P; Aurelia, RP. "Case Study: The Investigation of Drug Induced Liver Injury: A Case Study in In- patient of Internal Medicine Ward ." The International Conference on Health Practice and Research (ICHPR), vol. 3, 2022.

Risalati, PN; Alfarizi, Gilang Rizki; Lusia, P; Aurelia, RP. "Case Study: The Investigation of Drug Induced Liver Injury: A Case Study in In- patient of Internal Medicine Ward ." The International Conference on Health Practice and Research (ICHPR) 3 (2022).

Risalati, et al. (2022) 'Case Study: The Investigation of Drug Induced Liver Injury: A Case Study in In- patient of Internal Medicine Ward ', The International Conference on Health Practice and Research (ICHPR), 3.

Risalati, PN; Alfarizi, Gilang Rizki; Lusia, P; Aurelia, RP. Case Study: The Investigation of Drug Induced Liver Injury: A Case Study in In- patient of Internal Medicine Ward . The International Conference on Health Practice and Research (ICHPR). 2022;3.

Artikel Terkait

THE RELATIONSHIP BETWEEN WORK–LIFE BALANCE AND WORK STRESS ON THE QUALITY OF LIFE AMONG AMBULANCE OFFICERS IN SEMARANG CITY

Nissa Ade Lyana; Arlies Zenitha Victoriaa; Riris Risca Megawati

Development of Digital Communication Content Based on The Needs of Pregnant Women: A Qualitative Study

Ari Indra Susanti; Anis Novitasari; Harridhil Silmi; Qorinah Estiningtyas Sakilah Adnani

Application of the 4R Combination Therapy in Reducing Blood Pressure Among Clients with Hypertension

Margiyati

Comparative Effectiveness of Ultrasound and Static Stretching versus Myofascial Release on Pain Intensity in Cervical Myofascial Pain Syndrome

Syurrahmi

CLINICAL EFFECTIVENESS OF MHEALTH TECHNOLOGIES FOR ENHANCING POST STROKE FUNCTIONAL RECOVERY: A SYSTEMATIC LITERATURE REVIEW

Dwi Mulianda

IMPLEMENTATION OF FAMILY EDUCATION TO IMPROVE MEDICATION ADHERENCE AMONG CLIENTS WITH TYPE 2 DIABETES MELLITUS IN THE SRONDOL HEALTH CENTER AREA

Diana Dayaningsih; Arifah Nurhayati
Tren Sitasi Jurnal