Evaluation Immunological Parameters in Aborted Women with Toxoplasma Gondii

Toxoplasma gondii (T. gondii), intracellular parasite that cause abortion in infected pregnant women with the parasite. Aim of the study: the present investigation aimed to assessment the prevalence of T. gondii in aborted women and evaluated level of interferon- gamma, Toll-like receptor 2 (TLR2) and lactoferrin. Materials and methods: From September 2024 to May 2025, we examined 90 women, 70 of them spontaneous abortion, while an additional 20 blood samples were obtained from healthy individuals serving as controls, in Tikrit Teaching hospital and many private hospitals in Tikrit city. Result: The incidence of parasite infection in aborted women was 56 (80%) out of a total of 70%. The level of IFN, TLR2, and Lactoferrin in the group of aborted women infected with T. gondii (45.4 ±7.1, 17.04 ±2.28, 59.6±12.6), as compared with control group (19.4 ±2.12, 8.2 ±2.1, 29.2±9.4). Conclusion: The present study concluded increase prevalence of toxoplasma gondi in aborted woman may indicate the main cause of abortion. Furthermore, increase level of immunological parameters that may indicate resolve the parasite infection.